Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution
Authors
Keywords
-
Journal
Nature Communications
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-12-07
DOI
10.1038/ncomms9866
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature
- (2015) Henrik Sahlin Pettersen et al. DNA REPAIR
- Chromothripsis from DNA damage in micronuclei
- (2015) Cheng-Zhong Zhang et al. NATURE
- Recurrent targets of aberrant somatic hypermutation in lymphoma
- (2015) Alireza Hadj Khodabakhshi et al. Oncotarget
- High prevalence of somatic MAP2K1 mutations in BRAF V600E-negative Langerhans cell histiocytosis
- (2014) N. A. Brown et al. BLOOD
- Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients
- (2014) N. F. C. C. de Miranda et al. BLOOD
- AID induces intraclonal diversity and genomic damage in CD86+chronic lymphocytic leukemia cells
- (2014) Michael Huemer et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- APOBEC3 signature mutations in chronic lymphocytic leukemia
- (2014) S Rebhandl et al. LEUKEMIA
- Discovery and saturation analysis of cancer genes across 21 tumour types
- (2014) Michael S. Lawrence et al. NATURE
- Aberrant methylation and loss of CADM2 tumor suppressor expression is associated with human renal cell carcinoma tumor progression
- (2013) Wei He et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing
- (2013) R. D. Morin et al. BLOOD
- Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
- (2013) Dan A. Landau et al. CELL
- Punctuated Evolution of Prostate Cancer Genomes
- (2013) Sylvan C. Baca et al. CELL
- Criteria for Inference of Chromothripsis in Cancer Genomes
- (2013) Jan O. Korbel et al. CELL
- Regulation of AID, the B-cell genome mutator
- (2013) C. Keim et al. GENES & DEVELOPMENT
- Cancer Gene Discovery: Exploiting Insertional Mutagenesis
- (2013) Marco Ranzani et al. MOLECULAR CANCER RESEARCH
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
- (2013) Kristian Cibulskis et al. NATURE BIOTECHNOLOGY
- Deciphering Signatures of Mutational Processes Operative in Human Cancer
- (2013) Ludmil B. Alexandrov et al. Cell Reports
- Germinal Centers
- (2012) Gabriel D. Victora et al. Annual Review of Immunology
- Regulation ofAicdaexpression and AID activity
- (2012) Hong Zan et al. AUTOIMMUNITY
- RNA-SeQC: RNA-seq metrics for quality control and process optimization
- (2012) David S. DeLuca et al. BIOINFORMATICS
- IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions
- (2012) P. E. M. Patten et al. BLOOD
- Activation of Robo1 Signaling of Breast Cancer Cells by Slit2 from Stromal Fibroblast Restrains Tumorigenesis via Blocking PI3K/Akt/ -Catenin Pathway
- (2012) P.-H. Chang et al. CANCER RESEARCH
- Mutational Processes Molding the Genomes of 21 Breast Cancers
- (2012) Serena Nik-Zainal et al. CELL
- Integrative Genomic Analysis Implicates Gain of PIK3CA at 3q26 and MYC at 8q24 in Chronic Lymphocytic Leukemia
- (2012) J. R. Brown et al. CLINICAL CANCER RESEARCH
- Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability
- (2012) Y. Drier et al. GENOME RESEARCH
- Automatic Relevance Determination in Nonnegative Matrix Factorization with the /spl beta/-Divergence
- (2012) V. Y. F. Tan et al. IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE
- Molecular pathogenesis of chronic lymphocytic leukemia
- (2012) Gianluca Gaidano et al. JOURNAL OF CLINICAL INVESTIGATION
- Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase
- (2012) George Sharbeen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Independent coexistence of clones with 13q14 deletion at reciprocal translocation breakpoint and 13q14 interstitial deletion in chronic lymphocytic leukemia
- (2012) Martina Hruba et al. LEUKEMIA & LYMPHOMA
- Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions
- (2012) Steven A. Roberts et al. MOLECULAR CELL
- Analysis of Ig gene hypermutation in Ung−/−Polh−/− mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions
- (2012) Shuyin Li et al. MOLECULAR IMMUNOLOGY
- Clonal evolution in cancer
- (2012) Mel Greaves et al. NATURE
- Absolute quantification of somatic DNA alterations in human cancer
- (2012) Scott L Carter et al. NATURE BIOTECHNOLOGY
- Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
- (2012) Cole Trapnell et al. Nature Protocols
- Muscarinic receptor subtype-3 gene ablation and scopolamine butylbromide treatment attenuate small intestinal neoplasia in Apcmin/+ mice
- (2011) J.-P. Raufman et al. CARCINOGENESIS
- Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
- (2011) Philip J. Stephens et al. CELL
- Initial genome sequencing and analysis of multiple myeloma
- (2011) Michael A. Chapman et al. NATURE
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- Complex regulation and function of activation-induced cytidine deaminase
- (2011) Janet Stavnezer TRENDS IN IMMUNOLOGY
- A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries
- (2011) Sheila Fisher et al. GENOME BIOLOGY
- Novel Insights into the Biology of CLL
- (2011) M. C. Lanasa Hematology-American Society of Hematology Education Program
- Biological and clinical characterization of recurrent 14q deletions in CLL and other mature B-cell neoplasms
- (2010) Lena Reindl et al. BRITISH JOURNAL OF HAEMATOLOGY
- Diverse somatic mutation patterns and pathway alterations in human cancers
- (2010) Zhengyan Kan et al. NATURE
- Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes
- (2010) Arito Yamane et al. NATURE IMMUNOLOGY
- TopHat: discovering splice junctions with RNA-Seq
- (2009) Cole Trapnell et al. BIOINFORMATICS
- Frequency of 5′IGH deletions in B-cell chronic lymphocytic leukemia
- (2009) Fabiola Quintero-Rivera et al. CANCER GENETICS AND CYTOGENETICS
- Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
- (2008) M. Hallek et al. BLOOD
- Transcriptional pausing and stalling causes multiple clustered mutations by human activation-induced deaminase
- (2008) Chandrika Canugovi et al. FASEB JOURNAL
- Uracil in DNA and its processing by different DNA glycosylases
- (2008) T. Visnes et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now