Chlorotoxin: Structure, activity, and potential uses in cancer therapy

Temozolomide Nanoparticles for Targeted Glioblastoma Therapy

(2015) Chen Fang et al.   ACS Applied Materials & Interfaces

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma

(2015) Pedro M. Costa et al.   JOURNAL OF CONTROLLED RELEASE

Scorpion venom components as potential candidates for drug development

(2015) Ernesto Ortiz et al.   TOXICON

Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion

(2015) Lucie Dardevet et al.   Toxins

Redox-Responsive Magnetic Nanoparticle for Targeted Convection-Enhanced Delivery of O6-Benzylguanine to Brain Tumors

(2014) Zachary R. Stephen et al.   ACS Nano

Quantitative evaluation of the cell penetrating properties of an iodinated Tyr-l-maurocalcine analog

(2014) Céline Tisseyre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Scorpion venoms as a potential source of novel cancer therapeutic compounds

(2014) Jian Ding et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The role of disulfide bonds in structure and activity of chlorotoxin

(2014) Paola G Ojeda et al.   Future Medicinal Chemistry

A survey on “Trojan Horse” peptides: Opportunities, issues and controlled entry to “Troy”

(2014) Nian-Qiu Shi et al.   JOURNAL OF CONTROLLED RELEASE

OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma

(2014) Pei-jian Yue et al.   Molecular Cancer

Combination Treatment with Theranostic Nanoparticles for Glioblastoma Sensitization to TMZ

(2014) Byunghee Yoo et al.   MOLECULAR IMAGING AND BIOLOGY

Targeted delivery of silver nanoparticles and alisertib: in vitro and in vivo synergistic effect against glioblastoma

(2014) Erica Locatelli et al.   Nanomedicine

Near-infrared imaging of brain tumors using the Tumor Paint BLZ-100 to achieve near-complete resection of brain tumors

(2014) Pramod V. Butte et al.   Neurosurgical Focus

Characterization of IRDye 800CW chlorotoxin as a targeting agent for brain tumors

(2013) Joy L. Kovar et al.   ANALYTICAL BIOCHEMISTRY

Cyclotides as grafting frameworks for protein engineering and drug design applications

(2013) Aaron G. Poth et al.   BIOPOLYMERS

The insecticidal potential of venom peptides

(2013) Jennifer J. Smith et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Multifaceted Roles of Disulfide Bonds. Peptides as Therapeutics

(2013) Miriam Góngora-Benítez et al.   CHEMICAL REVIEWS

Cell-penetrating peptides: 20 years later, where do we stand?

(2013) Chérine Bechara et al.   FEBS LETTERS

Phase II Study of Alisertib, a Selective Aurora A Kinase Inhibitor, in Relapsed and Refractory Aggressive B- and T-Cell Non-Hodgkin Lymphomas

(2013) Jonathan W. Friedberg et al.   JOURNAL OF CLINICAL ONCOLOGY

Isolation of an Orally Active Insecticidal Toxin from the Venom of an Australian Tarantula

(2013) Margaret C. Hardy et al.   PLoS One

Clinical significance of annexin II expression in human non-small cell lung cancer

(2013) Jin-Wei Jia et al.   TUMOR BIOLOGY

Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment

(2013) Pedro M Costa et al.   Molecular Therapy-Nucleic Acids

Targeted nitric oxide delivery preferentially induces glioma cell chemosensitivity via altered p53 and O6-Methylguanine-DNA Methyltransferase activity

(2012) Shahana Safdar et al.   BIOTECHNOLOGY AND BIOENGINEERING

Clinical and prognostic role of annexin A2 in multiple myeloma

(2012) A. Seckinger et al.   BLOOD

The Future of Peptide-based Drugs

(2012) David J. Craik et al.   Chemical Biology & Drug Design

In Vivo Bio-imaging Using Chlorotoxin-based Conjugates

(2012) Mark R. Stroud et al.   CURRENT PHARMACEUTICAL DESIGN

Brain Tumors in Children- Current Therapies and Newer Directions

(2012) Soumen Khatua et al.   INDIAN JOURNAL OF PEDIATRICS

Platinum(IV)-chlorotoxin (CTX) conjugates for targeting cancer cells

(2012) Nora Graf et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Examination of blood–brain barrier (BBB) integrity in a mouse brain tumor model

(2012) Ngoc H. On et al.   JOURNAL OF NEURO-ONCOLOGY

Cell-penetrating peptides: breaking through to the other side

(2012) Erez Koren et al.   TRENDS IN MOLECULAR MEDICINE

Scorpion Toxins Specific for Potassium (K+) Channels: A Historical Overview of Peptide Bioengineering

(2012) Zachary Bergeron et al.   Toxins

Development of the research on the application of chlorotoxin in imaging diagnostics and targeted therapies for tumors

(2012) Xiao-Shan Wu et al.   Chinese Journal of Cancer

Clathrin-mediated entry and cellular localization of chlorotoxin in human glioma

(2011) Marzenna Wiranowska et al.   Cancer Cell International

Chlorotoxin-modified stealth liposomes encapsulating levodopa for the targeting delivery against the Parkinson’s disease in the MPTP-induced mice model

(2011) Yu Xiang et al.   JOURNAL OF DRUG TARGETING

Chemical Re-engineering of Chlorotoxin Improves Bioconjugation Properties for Tumor Imaging and Targeted Therapy

(2011) Muharrem Akcan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chlorotoxin-conjugated nanoparticles as potential glioma-targeted drugs

(2011) Yuejun Fu et al.   JOURNAL OF NEURO-ONCOLOGY

Purification, synthesis and characterization of AaCtx, the first chlorotoxin-like peptide from Androctonus australis scorpion venom

(2011) Ilhem Rjeibi et al.   PEPTIDES

Chlorotoxin Labeled Magnetic Nanovectors for Targeted Gene Delivery to Glioma

(2010) Forrest M. Kievit et al.   ACS Nano

Chlorotoxin bound magnetic nanovector tailored for cancer cell targeting, imaging, and siRNA delivery

(2010) Omid Veiseh et al.   BIOMATERIALS

Targeted delivery of chlorotoxin-modified DNA-loaded nanoparticles to glioma via intravenous administration

(2010) Rongqin Huang et al.   BIOMATERIALS

pH-Sensitive siRNA Nanovector for Targeted Gene Silencing and Cytotoxic Effect in Cancer Cells

(2010) Hyejung Mok et al.   MOLECULAR PHARMACEUTICS

A novel cyclopeptide from the cyclization of PACAP(1–5) with potent activity towards PAC1 attenuates STZ-induced diabetes

(2010) Rongjie Yu et al.   PEPTIDES

BmKCT toxin inhibits glioma proliferation and tumor metastasis

(2009) Shaozhong Fan et al.   CANCER LETTERS

Specific Targeting of Brain Tumors with an Optical/Magnetic Resonance Imaging Nanoprobe across the Blood-Brain Barrier

(2009) O. Veiseh et al.   CANCER RESEARCH

Annexin A2 Is a Molecular Target for TM601, a Peptide with Tumor-targeting and Anti-angiogenic Effects

(2009) Kamala Kesavan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A ligand-mediated nanovector for targeted gene delivery and transfection in cancer cells

(2008) Omid Veiseh et al.   BIOMATERIALS

Tumor-targeted drug delivery and MRI contrast enhancement by chlorotoxin-conjugated iron oxide nanoparticles

(2008) Conroy Sun et al.   Nanomedicine

In Vivo MRI Detection of Gliomas by Chlorotoxin-Conjugated Superparamagnetic Nanoprobes

(2008) Conroy Sun et al.   Small