Intracellular Environment Improvement of Mycobacterium neoaurum for Enhancing Androst-1,4-Diene-3,17-Dione Production by Manipulating NADH and Reactive Oxygen Species Levels

Identification of steroid C27 monooxygenase isoenzymes involved in sterol catabolism and stepwise pathway engineering of Mycobacterium neoaurum for improved androst-1,4-diene-3,17-dione production

(2019) Minglong Shao et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

New Insights on Steroid Biotechnology

(2018) Lorena Fernández-Cabezón et al.   Frontiers in Microbiology

Cofactor engineering to regulate NAD+/NADH ratio with its application to phytosterols biotransformation

(2017) Liqiu Su et al.   Microbial Cell Factories

Oxidative stress, protein damage and repair in bacteria

(2017) Benjamin Ezraty et al.   NATURE REVIEWS MICROBIOLOGY

Rapid measurement of phytosterols in fortified food using gas chromatography with flame ionization detection

(2016) Samantha Duong et al.   FOOD CHEMISTRY

Efficient testosterone production by engineered Pichia pastoris co-expressing human 17β-hydroxysteroid dehydrogenase type 3 and Saccharomyces cerevisiae glucose 6-phosphate dehydrogenase with NADPH regeneration

(2016) Minglong Shao et al.   GREEN CHEMISTRY

Efficient androst-1,4-diene-3,17-dione production by co-expressing 3-ketosteroid-Δ1-dehydrogenase and catalase inBacillus subtilis

(2016) M. Shao et al.   JOURNAL OF APPLIED MICROBIOLOGY

A mutant form of 3-ketosteroid-Δ1-dehydrogenase gives altered androst-1,4-diene-3, 17-dione/androst-4-ene-3,17-dione molar ratios in steroid biotransformations by Mycobacterium neoaurum ST-095

(2016) Minglong Shao et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Improvement of the intracellular environment for enhancing l -arginine production of Corynebacterium glutamicum by inactivation of H 2 O 2 -forming flavin reductases and optimization of ATP supply

(2016) Zaiwei Man et al.   METABOLIC ENGINEERING

Functional characterization of a mycothiol peroxidase inCorynebacterium glutamicumthat uses both mycoredoxin and thioredoxin reducing systems in the response to oxidative stress

(2015) Meiru Si et al.   BIOCHEMICAL JOURNAL

Metabolic engineering of cyanobacteria for the synthesis of commodity products

(2015) S. Andreas Angermayr et al.   TRENDS IN BIOTECHNOLOGY

The rebalanced pathway significantly enhances acetoin production by disruption of acetoin reductase gene and moderate-expression of a new water-forming NADH oxidase in Bacillus subtilis

(2014) Xian Zhang et al.   METABOLIC ENGINEERING

Efficient Whole-Cell Biocatalyst for Acetoin Production with NAD+ Regeneration System through Homologous Co-Expression of 2,3-Butanediol Dehydrogenase and NADH Oxidase in Engineered Bacillus subtilis

(2014) Teng Bao et al.   PLoS One

Accumulation of androstadiene-dione by overexpression of heterologous 3-ketosteroid Δ1-dehydrogenase in Mycobacterium neoaurum NwIB-01

(2014) Wei Wei et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

NrdH Redoxin Enhances Resistance to Multiple Oxidative Stresses by Acting as a Peroxidase Cofactor in Corynebacterium glutamicum

(2013) Mei-Ru Si et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bioconversion of 4-androstene-3,17-dione to androst-1,4-diene-3,17-dione by recombinant Bacillus subtilis expressing ksdd gene encoding 3-ketosteroid-Δ1-dehydrogenase from Mycobacterium neoaurum JC-12

(2013) Wenqing Zhang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Metabolic engineering of Escherichia coli to minimize byproduct formate and improving succinate productivity through increasing NADH availability by heterologous expression of NAD+-dependent formate dehydrogenase

(2013) Grant J. Balzer et al.   METABOLIC ENGINEERING

Cell Death from Antibiotics Without the Involvement of Reactive Oxygen Species

(2013) Y. Liu et al.   SCIENCE

Microbial steroid transformations: current state and prospects

(2012) Marina V. Donova et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Identification and engineering of cholesterol oxidases involved in the initial step of sterols catabolism in Mycobacterium neoaurum

(2012) Kang Yao et al.   METABOLIC ENGINEERING

Inactivation and Augmentation of the Primary 3-Ketosteroid- 1- Dehydrogenase in Mycobacterium neoaurum NwIB-01: Biotransformation of Soybean Phytosterols to 4-Androstene- 3,17-Dione or 1,4-Androstadiene-3,17-Dione

(2010) W. Wei et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Androstenedione production by biotransformation of phytosterols

(2008) Alok Malaviya et al.   BIORESOURCE TECHNOLOGY