Phosphorylation of nephrin induces phase separated domains that move through actomyosin contraction

A composition-dependent molecular clutch between T cell signaling condensates and actin

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Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and Beyond

(2018) Claire E. Martin et al.   Frontiers in Endocrinology

Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner

(2017) Jinsung Hong et al.   PLoS One

Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity

(2016) Menglong Zeng et al.   CELL

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Cortical actin and the plasma membrane: inextricably intertwined

(2016) Darius V Köster et al.   CURRENT OPINION IN CELL BIOLOGY

Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse

(2016) Sricharan Murugesan et al.   JOURNAL OF CELL BIOLOGY

Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture

(2016) L. A. New et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Actomyosin dynamics drive local membrane component organization in an in vitro active composite layer

(2016) Darius Vasco Köster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase separation of signaling molecules promotes T cell receptor signal transduction

(2016) Xiaolei Su et al.   SCIENCE

Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA

(2016) Diana M Mitrea et al.   eLife

Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro

(2016) Rakesh Verma et al.   PLoS One

Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies

(2015) Alpha S. Yap et al.   DEVELOPMENTAL CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck

(2015) Sudeep Banjade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasma membrane-associated platforms: Dynamic scaffolds that organize membrane-associated events

(2015) V. Astro et al.   Science Signaling

A dynamically coupled allosteric network underlies binding cooperativity in Src kinase

(2015) Zachariah H. Foda et al.   Nature Communications

Plasma membrane-associated platforms: Dynamic scaffolds that organize membrane-associated events

(2015) V. Astro et al.   Science Signaling

In Vitro Reconstitution of a Cellular Phase-Transition Process that Involves the mRNA Decapping Machinery

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Active organization of membrane constituents in living cells

(2014) Madan Rao et al.   CURRENT OPINION IN CELL BIOLOGY

TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures

(2014) Nadine Tarantino et al.   JOURNAL OF CELL BIOLOGY

Phase transitions of multivalent proteins can promote clustering of membrane receptors

(2014) Sudeep Banjade et al.   eLife

Eph/ephrin recognition and the role of Eph/ephrin clusters in signaling initiation

(2013) Dimitar B. Nikolov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Higher-Order Assemblies in a New Paradigm of Signal Transduction

(2013) Hao Wu   CELL

Modulation of T cell signaling by the actin cytoskeleton

(2013) Y. Yu et al.   JOURNAL OF CELL SCIENCE

Active Remodeling of Cortical Actin Regulates Spatiotemporal Organization of Cell Surface Molecules

(2012) Kripa Gowrishankar et al.   CELL

Large Protein Assemblies Formed by Multivalent Interactions between Cadherin23 and Harmonin Suggest a Stable Anchorage Structure at the Tip Link of Stereocilia

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Direct Regulation of Nephrin Tyrosine Phosphorylation by Nck Adaptor Proteins

(2012) Laura A. New et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells

(2012) Jason Yi et al.   MOLECULAR BIOLOGY OF THE CELL

Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model

(2012) Kolja Schleich et al.   MOLECULAR CELL

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Regulation from within: the cytoskeleton in transmembrane signaling

(2012) Khuloud Jaqaman et al.   TRENDS IN CELL BIOLOGY

Cell Biology and Pathology of Podocytes

(2011) Anna Greka et al.   Annual Review of Physiology

Signaling from the Living Plasma Membrane

(2011) Hernán E. Grecco et al.   CELL

Functional Nanoscale Organization of Signaling Molecules Downstream of the T Cell Antigen Receptor

(2011) Eilon Sherman et al.   IMMUNITY

Transforming binding affinities from three dimensions to two with application to cadherin clustering

(2011) Yinghao Wu et al.   NATURE

Hierarchical mesoscale domain organization of the plasma membrane

(2011) Akihiro Kusumi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Physical Mechanisms of Signal Integration by WASP Family Proteins

(2010) Shae B. Padrick et al.   Annual Review of Biochemistry

Mechanism of Induction of NK Activation by 2B4 (CD244) via Its Cognate Ligand

(2010) S. K. Sinha et al.   JOURNAL OF IMMUNOLOGY

Molecular mechanisms in signal transduction at the membrane

(2010) Jay T Groves et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nck Proteins Maintain the Adult Glomerular Filtration Barrier

(2009) N. Jones et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Phosphorylation of Nephrin Triggers Its Internalization by Raft-Mediated Endocytosis

(2009) X.-S. Qin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility

(2009) Ina Weisswange et al.   NATURE

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

Tracking microdomain dynamics in cell membranes

(2008) Charles A. Day et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

An introduction to critical points for biophysicists; observations of compositional heterogeneity in lipid membranes

(2008) Aurelia R. Honerkamp-Smith et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity

(2008) Debanjan Goswami et al.   CELL

Phosphorylated YDXV Motifs and Nck SH2/SH3 Adaptors Act Cooperatively To Induce Actin Reorganization

(2008) I. M. Blasutig et al.   MOLECULAR AND CELLULAR BIOLOGY

On the spontaneous emergence of cell polarity

(2008) Steven J. Altschuler et al.   NATURE