Zebrafish-Based Discovery of Antiseizure Compounds from the North Sea: Isoquinoline Alkaloids TMC-120A and TMC-120B

Zebrafish-Based Discovery of Antiseizure Compounds from the Red Sea: Pseurotin A2 and Azaspirofuran A

(2018) Daniëlle Copmans et al.   ACS Chemical Neuroscience

Methylated flavonoids as anti-seizure agents: Naringenin 4′,7-dimethyl ether attenuates epileptic seizures in zebrafish and mouse models

(2018) Daniëlle Copmans et al.   NEUROCHEMISTRY INTERNATIONAL

Instruction manual for the ILAE 2017 operational classification of seizure types

(2017) Robert S. Fisher et al.   EPILEPSIA

Marine microorganisms as a promising and sustainable source of bioactive molecules

(2017) G. Romano et al.   MARINE ENVIRONMENTAL RESEARCH

Application of Combination High-Throughput Phenotypic Screening and Target Identification Methods for the Discovery of Natural Product-Based Combination Drugs

(2017) Monica Isgut et al.   MEDICINAL RESEARCH REVIEWS

Animal Models of Seizures and Epilepsy: Past, Present, and Future Role for the Discovery of Antiseizure Drugs

(2017) Wolfgang Löscher   NEUROCHEMICAL RESEARCH

The National Institute of Neurological Disorders and Stroke (NINDS) Epilepsy Therapy Screening Program (ETSP)

(2017) John H. Kehne et al.   NEUROCHEMICAL RESEARCH

Validation of a Preclinical Drug Screening Platform for Pharmacoresistant Epilepsy

(2017) Melissa L. Barker-Haliski et al.   NEUROCHEMICAL RESEARCH

Retrospective analysis of natural products provides insights for future discovery trends

(2017) Cameron R. Pye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug development for refractory epilepsy: The past 25 years and beyond

(2017) Ambica Golyala et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Opportunities for improving animal welfare in rodent models of epilepsy and seizures

(2016) Katie Lidster et al.   JOURNAL OF NEUROSCIENCE METHODS

The marine biodiscovery pipeline and ocean medicines of tomorrow

(2016) Marcel Jaspars et al.   JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM

Assessment of Treatment Side Effects and Quality of Life in People with Epilepsy

(2016) Benjamin N. Blond et al.   NEUROLOGIC CLINICS

The Epidemiology of Global Epilepsy

(2016) Anuradha Singh et al.   NEUROLOGIC CLINICS

Drugs and Drug Candidates from Marine Sources: An Assessment of the Current “State of Play”

(2016) David Newman et al.   PLANTA MEDICA

Epilepsy: new advances

(2015) Solomon L Moshé et al.   LANCET

Animal models in epilepsy research: legacies and new directions

(2015) Brian P Grone et al.   NATURE NEUROSCIENCE

Zebrafish as tools for drug discovery

(2015) Calum A. MacRae et al.   NATURE REVIEWS DRUG DISCOVERY

Accurate Dereplication of Bioactive Secondary Metabolites from Marine-Derived Fungi by UHPLC-DAD-QTOFMS and a MS/HRMS Library

(2014) Sara Kildgaard et al.   Marine Drugs

Penicisochromans from the endophytic fungus Penicillium sp. BCC18034

(2014) Nantiya Bunbamrung et al.   Phytochemistry Letters

Tanshinone IIA Exhibits Anticonvulsant Activity in Zebrafish and Mouse Seizure Models

(2013) Olivia Erin Buenafe et al.   ACS Chemical Neuroscience

Natural products: A continuing source of novel drug leads

(2013) Gordon M. Cragg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Joint AES/ILAE translational workshop to optimize preclinical epilepsy research

(2013) Aristea S. Galanopoulou et al.   EPILEPSIA

Issues related to development of new antiseizure treatments

(2013) Karen S. Wilcox et al.   EPILEPSIA

Identification of Nonvisual Photomotor Response Cells in the Vertebrate Hindbrain

(2013) D. Kokel et al.   JOURNAL OF NEUROSCIENCE

Validation of the Zebrafish Pentylenetetrazol Seizure Model: Locomotor versus Electrographic Responses to Antiepileptic Drugs

(2013) Tatiana Afrikanova et al.   PLoS One

Epilepsy in kcnj10 Morphant Zebrafish Assessed with a Novel Method for Long-Term EEG Recordings

(2013) Anselm A. Zdebik et al.   PLoS One

Insights from Zebrafish and Mouse Models on the Activity and Safety of Ar-Turmerone as a Potential Drug Candidate for the Treatment of Epilepsy

(2013) Adriana Monserrath Orellana-Paucar et al.   PLoS One

Identification of new epilepsy treatments: Issues in preclinical methodology

(2012) Aristea S. Galanopoulou et al.   EPILEPSIA

Anticonvulsant activity of bisabolene sesquiterpenoids of Curcuma longa in zebrafish and mouse seizure models

(2012) Adriana Monserrath Orellana-Paucar et al.   EPILEPSY & BEHAVIOR

Effects of low molecular weight fungal compounds on inflammatory gene transcription and expression in mouse alveolar macrophages

(2011) Thomas. G. Rand et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Behavioral screening for neuroactive drugs in zebrafish

(2011) Jason Rihel et al.   Developmental Neurobiology

Secondary metabolites of fungi from marine habitats

(2011) Mostafa E. Rateb et al.   NATURAL PRODUCT REPORTS

Estimation of the burden of active and life-time epilepsy: A meta-analytic approach

(2010) Anthony K. Ngugi et al.   EPILEPSIA

Adverse effects of antiepileptic drugs: a brief overview of important issues

(2010) Joyce A Cramer et al.   Expert Review of Neurotherapeutics

Rapid behavior-based identification of neuroactive small molecules in the zebrafish

(2010) David Kokel et al.   Nature Chemical Biology

Inflammation-associated gene transcription and expression in mouse lungs induced by low molecular weight compounds from fungi from the built environment

(2009) J.D. Miller et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Sesquiterpenoids and Benzofuranoids from the Marine-Derived FungusAspergillus ustus094102

(2009) Zhenyu Lu et al.   JOURNAL OF NATURAL PRODUCTS

Antibacterial Activity of Marine Culturable Bacteria Collected from a Global Sampling of Ocean Surface Waters and Surface Swabs of Marine Organisms

(2009) Lone Gram et al.   MARINE BIOTECHNOLOGY

Secondary metabolites from Eurotium species, Aspergillus calidoustus and A. insuetus common in Canadian homes with a review of their chemistry and biological activities

(2009) Gregory J. Slack et al.  

Fishing for Drugs from Nature: Zebrafish as a Technology Platform for Natural Product Discovery

(2008) Alexander Crawford et al.   PLANTA MEDICA