Validation of a Preclinical Drug Screening Platform for Pharmacoresistant Epilepsy

The impact of nonadherence to antiseizure drugs on seizure outcomes in an animal model of epilepsy

(2017) Kyle E. Thomson et al.   EPILEPSIA

Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII)

(2017) Meir Bialer et al.   EPILEPSIA

Differential Effects of Antiepileptic Drugs on Focal Seizures in the Intrahippocampal Kainate Mouse Model of Mesial Temporal Lobe Epilepsy

(2016) Venceslas Duveau et al.   CNS Neuroscience & Therapeutics

Acute cognitive impact of antiseizure drugs in naive rodents and corneal-kindled mice

(2016) Melissa L. Barker-Haliski et al.   EPILEPSIA

Neuronal Injury, Gliosis, and Glial Proliferation in Two Models of Temporal Lobe Epilepsy

(2016) Jaycie L. Loewen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Biochemistry and Epigenetics of Epilepsy: Focus on Adenosine and Glycine

(2016) Detlev Boison   Frontiers in Molecular Neuroscience

Role(s) of the 5-HT2C Receptor in the Development of Maximal Dentate Activation in the Hippocampus of Anesthetized Rats

(2014) Gergely Orban et al.   CNS Neuroscience & Therapeutics

Low potency and limited efficacy of antiepileptic drugs in the mouse 6Hz corneal kindling model

(2014) K. Leclercq et al.   EPILEPSY RESEARCH

A novel open-source drug-delivery system that allows for first-of-kind simulation of nonadherence to pharmacological interventions in animal disease models

(2014) Kyle E. Thomson et al.   JOURNAL OF NEUROSCIENCE METHODS

Rapid loss of efficacy to the antiseizure drugs lamotrigine and carbamazepine: A novel experimental model of pharmacoresistant epilepsy

(2013) Ajay K. Srivastava et al.   EPILEPSIA

Should antidepressant drugs of the selective serotonin reuptake inhibitor family be tested as antiepileptic drugs?

(2013) Hamada Hamid et al.   EPILEPSY & BEHAVIOR

Overexpression of adenosine kinase in cortical astrocytes and focal neocortical epilepsy in mice

(2013) Hai-Ying Shen et al.   JOURNAL OF NEUROSURGERY

Carbamazepine, but not valproate, displays pharmacoresistance in lamotrigine-resistant amygdala kindled rats

(2012) Ajay K. Srivastava et al.   EPILEPSY RESEARCH

Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)

(2012) Meir Bialer et al.   EPILEPSY RESEARCH

Structural Sweet Spot for A1 Adenosine Receptor Activation by Truncated (N)-Methanocarba Nucleosides: Receptor Docking and Potent Anticonvulsant Activity

(2012) Dilip K. Tosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

White Coat Adherence over the First Year of Therapy in Pediatric Epilepsy

(2012) Avani C. Modi et al.   JOURNAL OF PEDIATRICS

Acetaminophen-induced liver injury in rats and mice: Comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity

(2012) Mitchell R. McGill et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Epilepsy and brain inflammation

(2011) Annamaria Vezzani et al.   EXPERIMENTAL NEUROLOGY

Adenosine dysfunction in epilepsy

(2011) Detlev Boison   GLIA

Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

(2011) Mattia Maroso et al.   Neurotherapeutics

The cognitive impact of antiepileptic drugs

(2011) Clare M. Eddy et al.   Therapeutic Advances in Neurological Disorders

Comparative anticonvulsant efficacy in the corneal kindled mouse model of partial epilepsy: Correlation with other seizure and epilepsy models

(2010) Nicole M. Rowley et al.   EPILEPSY RESEARCH

Acetaminophen inhibits status epilepticus in cultured hippocampal neurons

(2010) Laxmikant S. Deshpande et al.   NEUROREPORT

Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A

(2008) A Matagne et al.   BRITISH JOURNAL OF PHARMACOLOGY