Astaxanthin Suppresses Cigarette Smoke-Induced Emphysema through Nrf2 Activation in Mice

Protective effects of astaxanthin on skin: Recent scientific evidence, possible mechanisms, and potential indications

(2019) Kritarth Naman Singh et al.   Journal of Cosmetic Dermatology

A Polymorphism rs6726395 in Nrf2 Contributes to the Development of Emphysema-Associated Age in Smokers Without COPD

(2019) A. Sugitani et al.   LUNG

Role of Diet in Chronic Obstructive Pulmonary Disease Prevention and Treatment

(2019) Egeria Scoditti et al.   Nutrients

Anti-inflammatory effect of astaxanthin in phthalic anhydride-induced atopic dermatitis animal model

(2018) Ju Ho Park et al.   EXPERIMENTAL DERMATOLOGY

Astaxanthin Promotes Nrf2/ARE Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs

(2018) Qing Chen et al.   Marine Drugs

Astaxanthin Promotes Nrf2/ARE Signaling to Alleviate Renal Fibronectin and Collagen IV Accumulation in Diabetic Rats

(2018) Xiaoyu Zhu et al.   Journal of Diabetes Research

The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats

(2018) Yonghao Feng et al.   Frontiers in Pharmacology

Protective Effects of Oral Astaxanthin Nanopowder against Ultraviolet-Induced Photokeratitis in Mice

(2017) Fumiya Harada et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress in COPD: Sources, Markers, and Potential Mechanisms

(2017) Adam McGuinness et al.   Journal of Clinical Medicine

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Astaxanthin affects oxidative stress and hyposalivation in aging mice

(2016) Manatsu Kuraji et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Impaired nuclear factor erythroid 2-related factor 2 expression increases apoptosis of airway epithelial cells in patients with chronic obstructive pulmonary disease due to cigarette smoking

(2016) Kazuhiro Yamada et al.   BMC Pulmonary Medicine

Activation of the UPR Protects against Cigarette Smoke-induced RPE Apoptosis through Up-Regulation of Nrf2

(2015) Chuangxin Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Astaxanthin from Haematococcus pluvialis Prevents Oxidative Stress on Human Endothelial Cells without Toxicity

(2015) Philippe Régnier et al.   Marine Drugs

Targeting oxidant-dependent mechanisms for the treatment of COPD and its comorbidities

(2015) Ivan Bernardo et al.   PHARMACOLOGY & THERAPEUTICS

Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E

(2015) Yinhua Ni et al.   Scientific Reports

Astaxanthin inhibits apoptosis in alveolar epithelial cells type IIin vivo and in vitrothrough the ROS-dependent mitochondrial signalling pathway

(2014) Xiaodong Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The astaxanthin-induced improvement in lipid metabolism during exercise is mediated by a PGC-1α increase in skeletal muscle

(2014) Po Hung Liu et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Astaxanthin Activates Nuclear Factor Erythroid-Related Factor 2 and the Antioxidant Responsive Element (Nrf2-ARE) Pathway in the Brain after Subarachnoid Hemorrhage in Rats and Attenuates Early Brain Injury

(2014) Qi Wu et al.   Marine Drugs

Oxidative stress and free radicals in COPD – implications and relevance for treatment

(2014) Wolfgang Domej et al.   International Journal of Chronic Obstructive Pulmonary Disease

Oxidative Stress and Chromatin Remodeling in Chronic Obstructive Pulmonary Disease and Smoking-Related Diseases

(2012) Isaac K. Sundar et al.   ANTIOXIDANTS & REDOX SIGNALING

An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1: a longitudinal retrospective cohort study

(2011) Hironori Masuko et al.   BMC Medical Genetics

Marine Carotenoids and Cardiovascular Risk Markers

(2011) Graziano Riccioni et al.   Marine Drugs

Astaxanthin upregulates heme oxygenase-1 expression through ERK1/2 pathway and its protective effect against beta-amyloid-induced cytotoxicity in SH-SY5Y cells

(2010) Hong-Quan Wang et al.   BRAIN RESEARCH

Astaxanthin protects against MPTP/MPP+-induced mitochondrial dysfunction and ROS production in vivo and in vitro

(2010) Dae-Hee Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Deletion ofKeap1in the Lung Attenuates Acute Cigarette Smoke–Induced Oxidative Stress and Inflammation

(2009) David J. Blake et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Persistence of oxidant and protease burden in the airways after smoking cessation

(2009) Noora Louhelainen et al.   BMC Pulmonary Medicine

The Pathology of Chronic Obstructive Pulmonary Disease

(2008) James C. Hogg et al.   Annual Review of Pathology-Mechanisms of Disease

Protective effects of astaxanthin on 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells

(2008) Yasutaka Ikeda et al.   JOURNAL OF NEUROCHEMISTRY

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

(2008) T. E. Sussan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA