Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution profile

Metastasis Awakening: The challenges of targeting minimal residual cancer

(2013) Bernhard Polzer et al.   NATURE MEDICINE

Clinical drug resistance linked to interconvertible phenotypic and functional states of tumor-propagating cells in multiple myeloma

(2012) A. Chaidos et al.   BLOOD

Myeloma as a model for the process of metastasis: implications for therapy

(2012) I. M. Ghobrial   BLOOD

Characterization of potential CD138 negative myeloma "stem cells"

(2012) J. H. Christensen et al.   HAEMATOLOGICA

CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype

(2012) T. Paino et al.   HAEMATOLOGICA

CD138-negative clonogenic cells are plasma cells but not B cells in some multiple myeloma patients

(2012) N Hosen et al.   LEUKEMIA

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

(2012) L López-Corral et al.   LEUKEMIA

Clinical significance of CD81 expression by clonal plasma cells in high-risk smoldering and symptomatic multiple myeloma patients

(2012) B Paiva et al.   LEUKEMIA

High levels of peripheral blood circulating plasma cells as a specific risk factor for progression of smoldering multiple myeloma

(2012) G Bianchi et al.   LEUKEMIA

EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols

(2012) T Kalina et al.   LEUKEMIA

Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group

(2012) C Fernández de Larrea et al.   LEUKEMIA

CD19−CD45low/−CD38high/CD138+ plasma cells enrich for human tumorigenic myeloma cells

(2012) D Kim et al.   LEUKEMIA

Metastasis: The rude awakening

(2012) Jocelyn Rice   NATURE

RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis

(2012) Min Yu et al.   NATURE

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

The Proliferation Index of Specific Bone Marrow Cell Compartments from Myelodysplastic Syndromes Is Associated with the Diagnostic and Patient Outcome

(2012) Sergio Matarraz et al.   PLoS One

Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications

(2011) J. Jakubikova et al.   BLOOD

Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3

(2011) M. Dimopoulos et al.   BLOOD

The peripheral CD138+ population but not the CD138− population contains myeloma clonogenic cells in plasma cell leukaemia patients

(2011) David Chiron et al.   BRITISH JOURNAL OF HAEMATOLOGY

Soft-Tissue Plasmacytomas in Multiple Myeloma: Incidence, Mechanisms of Extramedullary Spread, and Treatment Approach

(2011) Joan Bladé et al.   JOURNAL OF CLINICAL ONCOLOGY

CD28 Expressed on Malignant Plasma Cells Induces a Prosurvival and Immunosuppressive Microenvironment

(2011) J. R. Nair et al.   JOURNAL OF IMMUNOLOGY

Competition between clonal plasma cells and normal cells for potentially overlapping bone marrow niches is associated with a progressively altered cellular distribution in MGUS vs myeloma

(2011) B Paiva et al.   LEUKEMIA

Evaluating the clonal hierarchy in light-chain multiple myeloma: implications against the myeloma stem cell hypothesis

(2011) S Pfeifer et al.   LEUKEMIA

Circulating plasma cells predict the outcome of relapsed or refractory multiple myeloma

(2011) Valdas Peceliunas et al.   LEUKEMIA & LYMPHOMA

CD117 expression in gammopathies is associated with an altered maturation of the myeloid and lymphoid hematopoietic cell compartments and favorable disease features

(2010) M. Schmidt-Hieber et al.   HAEMATOLOGICA

Circulating human B and plasma cells. Age-associated changes in counts and detailed characterization of circulating normal CD138- and CD138+ plasma cells

(2010) A. Caraux et al.   HAEMATOLOGICA

CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency

(2010) Menno C. van Zelm et al.   JOURNAL OF CLINICAL INVESTIGATION

Daratumumab, a Novel Therapeutic Human CD38 Monoclonal Antibody, Induces Killing of Multiple Myeloma and Other Hematological Tumors

(2010) M. de Weers et al.   JOURNAL OF IMMUNOLOGY

A monoclonal gammopathy precedes multiple myeloma in most patients

(2009) B. M. Weiss et al.   BLOOD

Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study

(2009) O. Landgren et al.   BLOOD

Prognostic Significance of Copy-Number Alterations in Multiple Myeloma

(2009) Hervé Avet-Loiseau et al.   JOURNAL OF CLINICAL ONCOLOGY

Blood-borne human plasma cells in steady state are derived from mucosal immune responses

(2008) H. E. Mei et al.   BLOOD

Clonogenic Multiple Myeloma Progenitors, Stem Cell Properties, and Drug Resistance

(2008) W. Matsui et al.   CANCER RESEARCH

Prognostic Value of Immunophenotyping in Multiple Myeloma: A Study by the PETHEMA/GEM Cooperative Study Groups on Patients Uniformly Treated With High-Dose Therapy

(2008) Gema Mateo et al.   JOURNAL OF CLINICAL ONCOLOGY

Haematopoietic stem cell release is regulated by circadian oscillations

(2008) Simón Méndez-Ferrer et al.   NATURE