Destress and do not suppress: targeting adrenergic signaling in tumor immunosuppression

Brain Tumor Microenvironment and Host State: Implications for Immunotherapy

(2019) William Tomaszewski et al.   CLINICAL CANCER RESEARCH

β2 adrenergic receptor–mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells

(2019) Hemn Mohammadpour et al.   JOURNAL OF CLINICAL INVESTIGATION

STAT3 in Tumor-Associated Myeloid Cells: Multitasking to Disrupt Immunity

(2018) Yu-Lin Su et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blockade of Host β2-Adrenergic Receptor Enhances Graft-versus-Tumor Effect through Modulating APCs

(2018) Hemn Mohammadpour et al.   JOURNAL OF IMMUNOLOGY

Adrenergic Signaling: A Targetable Checkpoint Limiting Development of the Antitumor Immune Response

(2018) Guanxi Qiao et al.   Frontiers in Immunology

Propranolol for Off-label Treatment of Patients With Melanoma

(2018) Vincenzo De Giorgi et al.   JAMA Oncology

Beta blocker use correlates with better overall survival in metastatic melanoma patients and improves the efficacy of immunotherapies in mice

(2017) Kathleen M. Kokolus et al.   OncoImmunology

Sympathetic neural signaling via the β2-adrenergic receptor suppresses T-cell receptor-mediated human and mouse CD8+ T-cell effector function

(2016) Leonardo D. Estrada et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation

(2016) Vinit Kumar et al.   IMMUNITY

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice

(2016) Dominic Schmidt et al.   PLoS One

Catecholamines and acetylcholine are key regulators of the interaction between microbes and the immune system

(2015) Leon Islas Weinstein et al.   Annals of the New York Academy of Sciences

Tumor microenvironment: Sanctuary of the devil

(2015) Lanlan Hui et al.   CANCER LETTERS

Molecular Mechanisms Underlying β-Adrenergic Receptor-Mediated Cross-Talk between Sympathetic Neurons and Immune Cells

(2015) Dianne Lorton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immunotherapy for cancer in the central nervous system: Current and future directions

(2015) David C. Binder et al.   OncoImmunology

A nervous tumor microenvironment: the impact of adrenergic stress on cancer cells, immunosuppression, and immunotherapeutic response

(2014) Jason W.-L. Eng et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Myeloid-Derived Suppressor Activity Is Mediated by Monocytic Lineages Maintained by Continuous Inhibition of Extrinsic and Intrinsic Death Pathways

(2014) Jessica M. Haverkamp et al.   IMMUNITY

Autonomic Nerve Development Contributes to Prostate Cancer Progression

(2013) C. Magnon et al.   SCIENCE

Mechanism of T Cell Tolerance Induced by Myeloid-Derived Suppressor Cells

(2010) S. Nagaraj et al.   JOURNAL OF IMMUNOLOGY