Sphingosine‐1‐phosphate receptor 2 modulates pain sensitivity by suppressing the ROS‐RUNX3 pathway in a rat model of neuropathy

Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosis

(2018) Carlo Mümmler et al.   FASEB JOURNAL

Cytoplasmic Localization of RUNX3 via Histone Deacetylase-Mediated SRC Expression in Oxidative-Stressed Colon Cancer Cells

(2017) Kyoung Ah Kang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Reactive oxygen species affect spinal cell type-specific synaptic plasticity in a model of neuropathic pain

(2017) Alice Bittar et al.   PAIN

Ginkgolide B Protects Against Ischemic Stroke Via Modulating Microglia Polarization in Mice

(2016) Zhao-Ma Shu et al.   CNS Neuroscience & Therapeutics

Inhibition of YAP/TAZ Activity in Spinal Cord Suppresses Neuropathic Pain

(2016) N. Xu et al.   JOURNAL OF NEUROSCIENCE

Interleukin-1β overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents

(2016) Wen-Shan Gui et al.   Molecular Pain

Morin Mitigates Chronic Constriction Injury (CCI)-Induced Peripheral Neuropathy by Inhibiting Oxidative Stress Induced PARP Over-Activation and Neuroinflammation

(2016) Prashanth Komirishetty et al.   NEUROCHEMICAL RESEARCH

Spinal mitochondrial-derived ROS contributes to remifentanil-induced postoperative hyperalgesia via modulating NMDA receptor in rats

(2016) Liu Ye et al.   NEUROSCIENCE LETTERS

Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death: implications for otoprotective therapy

(2016) Deron R. Herr et al.   Scientific Reports

Runx3-regulated expression of two Ntrk3 transcript variants in dorsal root ganglion neurons

(2015) Yuuki Ogihara et al.   Developmental Neurobiology

Hyperbaric oxygenation treatment alleviates CCI-induced neuropathic pain and decreases spinal apoptosis

(2014) Q. Hu et al.   EUROPEAN JOURNAL OF PAIN

Atorvastatin attenuates neuropathic pain in rat neuropathy model by down-regulating oxidative damage at peripheral, spinal and supraspinal levels

(2014) Nitya N. Pathak et al.   NEUROCHEMISTRY INTERNATIONAL

RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation

(2014) Woosook Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Sphingolipid Receptor S1PR2 Is a Receptor for Nogo-A Repressing Synaptic Plasticity

(2014) Anissa Kempf et al.   PLOS BIOLOGY

Sphingosine 1-phosphate signalling

(2013) K. Mendelson et al.   DEVELOPMENT

Sphingosine-1-phosphate receptor 2

(2013) Mohamad Adada et al.   FEBS Journal

Oxidative stress induces proliferation of colorectal cancer cells by inhibiting RUNX3 and activating the Akt signaling pathway

(2013) KYOUNG AH KANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Endogenous Interleukin-1β in Neuropathic Rats Enhances Glutamate Release from the Primary Afferents in the Spinal Dorsal Horn through Coupling with PresynapticN-Methyl-d-aspartic Acid Receptors

(2013) Xisheng Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive oxygen species contribute to neuropathic pain and locomotor dysfunction via activation of CamKII in remote segments following spinal cord contusion injury in rats

(2013) Young S. Gwak et al.   PAIN

Neuropathic pain in the general population: A systematic review of epidemiological studies

(2013) O. van Hecke et al.   PAIN

Runt-related transcription factor 2 (RUNX2) inhibits p53-dependent apoptosis through the collaboration with HDAC6 in response to DNA damage

(2013) T Ozaki et al.   Cell Death & Disease

Positional differences of axon growth rates between sensory neurons encoded by runx3

(2012) Francois Lallemend et al.   EMBO JOURNAL

NADPH Oxidase-4 Maintains Neuropathic Pain after Peripheral Nerve Injury

(2012) W. Kallenborn-Gerhardt et al.   JOURNAL OF NEUROSCIENCE

Deconstructing the Neuropathic Pain Phenotype to Reveal Neural Mechanisms

(2012) Christian A. von Hehn et al.   NEURON

Molecular targeting of NOX4 for neuropathic pain after traumatic injury of the spinal cord

(2012) Y B Im et al.   Cell Death & Disease

Sphingosine-1-phosphate acting via the S1P1 receptor is a downstream signaling pathway in ceramide-induced hyperalgesia

(2011) Tim Doyle et al.   NEUROSCIENCE LETTERS

Genetic Evidence for Involvement of Neuronally Expressed S1P1 Receptor in Nociceptor Sensitization and Inflammatory Pain

(2011) Norbert Mair et al.   PLoS One

Pain and death: Neurodegenerative disease mechanisms in the nociceptor

(2010) David B. Reichling et al.   ANNALS OF NEUROLOGY

Runt-Related Transcription Factor RUNX3 Is a Target of MDM2-Mediated Ubiquitination

(2009) X.-Z. Chi et al.   CANCER RESEARCH

Dynamic regulation of the expression of neurotrophin receptors by Runx3

(2008) S. Nakamura et al.   DEVELOPMENT

CCL2 is a key mediator of microglia activation in neuropathic pain states

(2008) Michael A. Thacker et al.   EUROPEAN JOURNAL OF PAIN