MicroRNAs as Potential Biomarkers in Atherosclerosis

Abstract WP541: Profiling of Microrna From Atherosclerotic Tissues and Validation of Their Significance From Peripheral Blood of Ischemic Stroke Patients Having Atherosclerosis

(2019) Hye Seon Jeong et al.   STROKE

MicroRNAs as novel biomarkers for colorectal cancer: New outlooks

(2018) Naghmeh Shirafkan et al.   BIOMEDICINE & PHARMACOTHERAPY

Expression Profiles of Six Atherosclerosis-Associated microRNAs That Cluster in Patients with Hyperhomocysteinemia: A Clinical Study

(2018) Kejian Liu et al.   DNA AND CELL BIOLOGY

Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases

(2018) Maria Angela Incalza et al.   VASCULAR PHARMACOLOGY

The interplay of LncRNA ANRIL and miR-181b on the inflammation-relevant coronary artery disease through mediating NF-κB signalling pathway

(2018) Feng Guo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

miR-125a Suppresses TrxR1 Expression and Is Involved in H2O2-Induced Oxidative Stress in Endothelial Cells

(2018) Fangjie Chen et al.   Journal of Immunology Research

Role of microRNAs in obesity and obesity-related diseases

(2017) Giuseppe Iacomino et al.   Genes and Nutrition

FDA-Approved Oligonucleotide Therapies in 2017

(2017) Cy A. Stein et al.   MOLECULAR THERAPY

Biogenesis and Function of Ago-Associated RNAs

(2017) Iben Daugaard et al.   TRENDS IN GENETICS

MicroRNA in cardiovascular biology and disease

(2017) Anna Wojciechowska et al.   Advances in Clinical and Experimental Medicine

Role of microRNAs in obesity and obesity-related diseases

(2017) Giuseppe Iacomino et al.   Genes and Nutrition

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic LesionsNovelty and Significance

(2016) Suzanne M. Eken et al.   CIRCULATION RESEARCH

MicroRNAs modulating angiogenesis: miR-129-1 and miR-133 act as angio-miR in HUVECs

(2016) Mina Soufi-zomorrod et al.   TUMOR BIOLOGY

Concise Review: Functional Definition of Endothelial Progenitor Cells: A Molecular Perspective

(2016) Jatin Patel et al.   Stem Cells Translational Medicine

Relation Between Adolescent Cardiovascular Risk Factors and Carotid Intima‐Media Echogenicity in Healthy Young Adults: The Atherosclerosis Risk in Young Adults (ARYA) Study

(2016) Anouk L. M. Eikendal et al.   Journal of the American Heart Association

miR-155 acts as an anti-inflammatory factor in atherosclerosis-associated foam cell formation by repressing calcium-regulated heat stable protein 1

(2016) Xiaoyi Li et al.   Scientific Reports

MiR-126 inhibits vascular endothelial cell apoptosis through targeting PI3K/Akt signaling

(2015) Lingqiang Chen et al.   ANNALS OF HEMATOLOGY

MicroRNA-155 Promotes Atherosclerosis Inflammation via Targeting SOCS1

(2015) Yang Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Endothelial Cell Autophagy in Atherosclerosis is Regulated by miR-30-Mediated Translational Control of ATG6

(2015) Tao Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Ageing, metabolism and cardiovascular disease

(2015) Sarah Costantino et al.   JOURNAL OF PHYSIOLOGY-LONDON

MicroRNA-495 regulates the proliferation and apoptosis of human umbilical vein endothelial cells by targeting chemokine CCL2

(2015) Dan Liu et al.   THROMBOSIS RESEARCH

MiR-132 Inhibits Expression of SIRT1 and Induces Pro-inflammatory Processes of Vascular Endothelial Inflammation through Blockade of the SREBP-1c Metabolic Pathway

(2014) Liwei Zhang et al.   CARDIOVASCULAR DRUGS AND THERAPY

miR126-5p repression of ALCAM and SetD5 in endothelial cells regulates leucocyte adhesion and transmigration

(2014) Loïc Poissonnier et al.   CARDIOVASCULAR RESEARCH

Healthy Lifestyle Change and Subclinical Atherosclerosis in Young Adults

(2014) Bonnie Spring et al.   CIRCULATION

Emerging Role of MicroRNAs in Cardiovascular Diseases

(2014) Salvatore De Rosa et al.   CIRCULATION JOURNAL

miR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment

(2014) Ping Wen et al.   EXPERIMENTAL CELL RESEARCH

β-Blocker carvedilol protects cardiomyocytes against oxidative stress-induced apoptosis by up-regulating miR-133 expression

(2014) Chaoqian Xu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats

(2014) Hui Cao et al.   JOURNAL OF SURGICAL RESEARCH

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1

(2014) Andreas Schober et al.   NATURE MEDICINE

MiR-9 reduces human acyl-coenzyme A:cholesterol acyltransferase-1 to decrease THP-1 macrophage-derived foam cell formation

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miR181a protects against angiotensin II-induced osteopontin expression in vascular smooth muscle cells

(2013) Ebony Washington Remus et al.   ATHEROSCLEROSIS

Increased expression of microRNA-221 inhibits PAK1 in endothelial progenitor cells and impairs its function via c-Raf/MEK/ERK pathway

(2013) Xiaoping Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-424/322 regulates vascular smooth muscle cell phenotype and neointimal formation in the rat

(2013) Elise Merlet et al.   CARDIOVASCULAR RESEARCH

MicroRNAs in flow-dependent vascular remodelling

(2013) Peter Neth et al.   CARDIOVASCULAR RESEARCH

The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155 –Dependent Pathway During Atherosclerosis

(2013) Yuanyuan Wei et al.   CIRCULATION

MicroRNA-663 Regulates Human Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Neointimal Formation

(2013) Pan Li et al.   CIRCULATION RESEARCH

Systemic Delivery of MicroRNA-181b Inhibits Nuclear Factor-κB Activation, Vascular Inflammation, and Atherosclerosis in Apolipoprotein E–Deficient Mice

(2013) Xinghui Sun et al.   CIRCULATION RESEARCH

Endothelial MicroRNAs and Atherosclerosis

(2013) Xinghui Sun et al.   Current Atherosclerosis Reports

Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats

(2013) Hongqi Xin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Platelet-Secreted MicroRNA-223 Promotes Endothelial Cell Apoptosis Induced by Advanced Glycation End Products via Targeting the Insulin-like Growth Factor 1 Receptor

(2013) Y. Pan et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart

(2013) Zoltán V. Varga et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mipomersen, an Apolipoprotein B Synthesis Inhibitor, Reduces Atherogenic Lipoproteins in Patients With Severe Hypercholesterolemia at High Cardiovascular Risk

(2013) Gregory S. Thomas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Let-7g Improves Multiple Endothelial Functions Through Targeting Transforming Growth Factor-Beta and SIRT-1 Signaling

(2013) Yi-Chu Liao et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

MicroRNA-34a regulates cardiac ageing and function

(2013) Reinier A. Boon et al.   NATURE

MicroRNAs as pharmacological targets in endothelial cell function and dysfunction

(2013) Aránzazu Chamorro-Jorganes et al.   PHARMACOLOGICAL RESEARCH

Systemic Delivery of shRNA by AAV9 Provides Highly Efficient Knockdown of Ubiquitously Expressed GFP in Mouse Heart, but Not Liver

(2013) Bryan A. Piras et al.   PLoS One

Upregulation of a Disintegrin and Metalloproteinase With Thrombospondin Motifs-7 by miR-29 Repression Mediates Vascular Smooth Muscle Calcification

(2012) Yaoyao Du et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA-21 Modulates the Levels of Reactive Oxygen Species by Targeting SOD3 and TNF 

(2012) X. Zhang et al.   CANCER RESEARCH

Developing MicroRNA Therapeutics

(2012) Eva van Rooij et al.   CIRCULATION RESEARCH

MicroRNA-181b regulates NF-κB–mediated vascular inflammation

(2012) Xinghui Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

microRNA-181a represses ox-LDL-stimulated inflammatory response in dendritic cell by targeting c-Fos

(2012) Chaoneng Wu et al.   JOURNAL OF LIPID RESEARCH

MicroRNAs and atherosclerosis: New actors for an old movie

(2012) D. Santovito et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Passenger strand miRNA miR-31∗ regulates the phenotypes of oral cancer cells by targeting RhoA

(2012) Kuo-Wei Chang et al.   ORAL ONCOLOGY

Regulation of MicroRNA-155 in Atherosclerotic Inflammatory Responses by Targeting MAP3K10

(2012) Jianhua Zhu et al.   PLoS One

MicroRNAs regulating lipid metabolism in atherogenesis

(2012) Katey J. Rayner et al.   THROMBOSIS AND HAEMOSTASIS

Atheroprotective mechanisms of shear stress-regulated microRNAs

(2012) Reinier A. Boon et al.   THROMBOSIS AND HAEMOSTASIS

The role of microRNAs in arterial remodelling

(2012) Maliheh Nazari-Jahantigh et al.   THROMBOSIS AND HAEMOSTASIS

miR-125b Regulates Calcification of Vascular Smooth Muscle Cells

(2011) Claudia Goettsch et al.   AMERICAN JOURNAL OF PATHOLOGY

MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells

(2011) Chih-Wen Ni et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1

(2011) Cristina M. Ramirez et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

miR-146a is modulated in human endothelial cell with aging

(2011) Mariuca Vasa-Nicotera et al.   ATHEROSCLEROSIS

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

(2011) Emma Raitoharju et al.   ATHEROSCLEROSIS

MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A

(2011) C. Urbich et al.   BLOOD

MicroRNA-145 in vascular smooth muscle cell biology: A new therapeutic target for vascular disease

(2011) Chunxiang Zhang   CELL CYCLE

miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition

(2011) A Magenta et al.   CELL DEATH AND DIFFERENTIATION

Circulating MicroRNAs in Cardiovascular Disease

(2011) David D. McManus et al.   CIRCULATION

Vascular Smooth Muscle Cell Proliferation Is Influenced by let-7d MicroRNA and Its Interaction With KRAS

(2011) Man-Li Yu et al.   CIRCULATION JOURNAL

MicroRNA-133 Controls Vascular Smooth Muscle Cell Phenotypic Switch In Vitro and Vascular Remodeling In Vivo

(2011) Daniele Torella et al.   CIRCULATION RESEARCH

MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4

(2011) Ke Yang et al.   FEBS LETTERS

Negative feedback regulation between microRNA let-7g and the oxLDL receptor LOX-1

(2011) K.-C. Chen et al.   JOURNAL OF CELL SCIENCE

Bone marrow mesenchymal stem cells for post-myocardial infarction cardiac repair: microRNAs as novel regulators

(2011) Zhuzhi Wen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Characterization of extracellular circulating microRNA

(2011) Andrey Turchinovich et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-21 targets peroxisome proliferators-activated receptor-  in an autoregulatory loop to modulate flow-induced endothelial inflammation

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Unique MicroRNA Signature Associated With Plaque Instability in Humans

(2011) Francesco Cipollone et al.   STROKE

MicroRNAs Are Necessary for Vascular Smooth Muscle Growth, Differentiation, and Function

(2010) Sebastian Albinsson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction

(2010) Benjamin Meder et al.   BASIC RESEARCH IN CARDIOLOGY

MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity

(2010) Martina Weber et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-34a regulation of endothelial senescence

(2010) Takashi Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Circulating MicroRNAs in Patients With Coronary Artery Disease

(2010) Stephan Fichtlscherer et al.   CIRCULATION RESEARCH

Identification of miR-130a, miR-27b and miR-210 as serum biomarkers for atherosclerosis obliterans

(2010) Tianrun Li et al.   CLINICA CHIMICA ACTA

The MicroRNA Spectrum in 12 Body Fluids

(2010) J. A. Weber et al.   CLINICAL CHEMISTRY

Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans

(2010) Guo-Kun Wang et al.   EUROPEAN HEART JOURNAL

Structure-Functional Analyses of CRHSP-24 Plasticity and Dynamics in Oxidative Stress Response

(2010) Hai Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of miR-33 from anSREBP2Intron Inhibits Cholesterol Export and Fatty Acid Oxidation

(2010) Isabelle Gerin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism

(2010) Dimitrios Iliopoulos et al.   JOURNAL OF LIPID RESEARCH

Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production

(2010) Keita Miyoshi et al.   MOLECULAR GENETICS AND GENOMICS

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth

(2010) K.-C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-33 links SREBP-2 induction to repression of sterol transporters

(2010) T. J. Marquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro

(2010) Y. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Widespread regulatory activity of vertebrate microRNA* species

(2010) J.-S. Yang et al.   RNA

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

Role of Specific MicroRNAs in Regulation of Vascular Smooth Muscle Cell Differentiation and the Response to Injury

(2010) Zifang Song et al.   Journal of Cardiovascular Translational Research

MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages

(2009) Ting Chen et al.   CARDIOVASCULAR RESEARCH

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease

(2009) L Elia et al.   CELL DEATH AND DIFFERENTIATION

MicroRNA 217 Modulates Endothelial Cell Senescence via Silent Information Regulator 1

(2009) Rossella Menghini et al.   CIRCULATION

MicroRNA-145, a Novel Smooth Muscle Cell Phenotypic Marker and Modulator, Controls Vascular Neointimal Lesion Formation

(2009) Yunhui Cheng et al.   CIRCULATION RESEARCH

A Necessary Role of miR-221 and miR-222 in Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia

(2009) Xiaojun Liu et al.   CIRCULATION RESEARCH

Plasma oxidized lipoprotein(a) and its immune complexes are present in newborns and children

(2009) Junjun Wang et al.   CLINICA CHIMICA ACTA

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

(2009) M. Xin et al.   GENES & DEVELOPMENT

Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster

(2009) Thomas Boettger et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: TNF-Induced MicroRNAs Regulate TNF-Induced Expression of E-Selectin and Intercellular Adhesion Molecule-1 on Human Endothelial Cells: Feedback Control of Inflammation

(2009) Yajaira Suárez et al.   JOURNAL OF IMMUNOLOGY

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

(2009) Kimberly R. Cordes et al.   NATURE

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

(2009) G. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

(2009) A. Bonauer et al.   SCIENCE

Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

(2009) A. Zernecke et al.   Science Signaling

Innate and adaptive immunity in atherosclerosis

(2009) René R. S. Packard et al.   Seminars in Immunopathology

Endothelial Cell Apoptosis is Responsible for the Formation of Coronary Thrombotic Atherosclerotic Plaques

(2009) Feng Xu et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA and vascular smooth muscle cell phenotype: new therapy for atherosclerosis?

(2009) Chunxiang Zhang   Genome Medicine

The Pathology of Atherosclerosis: Plaque Development and Plaque Responses to Medical Treatment

(2008) William Insull   AMERICAN JOURNAL OF MEDICINE

Role of microRNAs in diabetes

(2008) X TANG et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Downregulation of miR-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines

(2008) Shingo Mitomo et al.   CANCER SCIENCE

Vascular repair by endothelial progenitor cells

(2008) A. Zampetaki et al.   CARDIOVASCULAR RESEARCH

HDL, ABC Transporters, and Cholesterol Efflux: Implications for the Treatment of Atherosclerosis

(2008) Alan R. Tall et al.   Cell Metabolism

The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

(2008) Shusheng Wang et al.   DEVELOPMENTAL CELL

microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart

(2008) N. Liu et al.   GENES & DEVELOPMENT

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

(2008) Jonathan B. Johnnidis et al.   NATURE

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

(2008) Melissa Piper Hunter et al.   PLoS One

Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis

(2008) Y. Suarez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting microRNA expression to regulate angiogenesis

(2007) Angelika Kuehbacher et al.   TRENDS IN PHARMACOLOGICAL SCIENCES