Systemic Delivery of shRNA by AAV9 Provides Highly Efficient Knockdown of Ubiquitously Expressed GFP in Mouse Heart, but Not Liver

Adeno-associated virus serotype 9 administered systemically after reperfusion preferentially targets cardiomyocytes in the infarct border zone with pharmacodynamics suitable for the attenuation of left ventricular remodeling

(2012) Prasad R. Konkalmatt et al.   JOURNAL OF GENE MEDICINE

Glycan Binding Avidity Determines the Systemic Fate of Adeno-Associated Virus Type 9

(2012) S. Shen et al.   JOURNAL OF VIROLOGY

Terminal Differentiation of Cardiac and Skeletal Myocytes Induces Permissivity to AAV Transduction by Relieving Inhibition Imposed by DNA Damage Response Proteins

(2012) Jasmina Lovric et al.   MOLECULAR THERAPY

Heart Failure-Inducible Gene Therapy Targeting Protein Phosphatase 1 Prevents Progressive Left Ventricular Remodeling

(2012) Yosuke Miyazaki et al.   PLoS One

AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction-Induced Heart Failure

(2012) Chang Sik Park et al.   PLoS One

Intraperitoneal AAV9-shRNA inhibits target expression in neonatal skeletal and cardiac muscles

(2011) Azat Mayra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution

(2010) K-M R Prasad et al.   GENE THERAPY

Transient expression of genes delivered to newborn rat liver using recombinant adeno-associated virus 2/8 vectors

(2009) Maude Flageul et al.   JOURNAL OF GENE MEDICINE

Behind the Scenes of a Small RNA Gene-Silencing Pathway

(2008) Gregory Ku et al.   HUMAN GENE THERAPY

Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins

(2008) T. Cervelli et al.   JOURNAL OF CELL SCIENCE

Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy

(2008) Henry Fechner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Gene Delivery to the Juvenile Mouse Liver Using AAV2/8 Vectors

(2008) Sharon C Cunningham et al.   MOLECULAR THERAPY

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

(2008) Carmela Zincarelli et al.   MOLECULAR THERAPY