Ginsenoside Rb1 Attenuates High Glucose-Induced Oxidative Injury via the NAD-PARP-SIRT Axis in Rat Retinal Capillary Endothelial Cells

The MTT-formazan assay: Complementary technical approaches and in vivo validation in Drosophila larvae

(2018) Raquel Pascua-Maestro et al.   ACTA HISTOCHEMICA

NAD+ Deficiency Is a Common Central Pathological Factor of a Number of Diseases and Aging: Mechanisms and Therapeutic Implications

(2018) Mingchao Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

NMNAT1 E257K variant, associated with Leber Congenital Amaurosis (LCA9), causes a mild retinal degeneration phenotype

(2018) Aiden Eblimit et al.   EXPERIMENTAL EYE RESEARCH

Antioxidants and HNE in redox homeostasis

(2017) Wojciech Łuczaj et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ginsenoside Rb1 exerts antidiabetic action on C2C12 muscle cells by leptin receptor signaling pathway

(2017) Mohammad Reza Tabandeh et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction

(2017) Yi Zhang et al.   Cell Death & Disease

Notoginsenoside R1 attenuates high glucose-induced endothelial damage in rat retinal capillary endothelial cells by modulating the intracellular redox state

(2017) Chunlan Fan et al.   Drug Design Development and Therapy

mGluR2/3 activation of the SIRT1 axis preserves mitochondrial function in diabetic neuropathy

(2017) Krish Chandrasekaran et al.   Annals of Clinical and Translational Neurology

Nrf2/antioxidant defense pathway is involved in the neuroprotective effects of Sirt1 against focal cerebral ischemia in rats after hyperbaric oxygen preconditioning

(2016) Fen Xue et al.   BEHAVIOURAL BRAIN RESEARCH

Ginsenoside Rb1 as a neuroprotective agent: A review

(2016) Touqeer Ahmed et al.   BRAIN RESEARCH BULLETIN

SIRT1 exerts protective effects against paraquat-induced injury in mouse type II alveolar epithelial cells by deacetylating NRF2 in vitro

(2016) YING-WEI DING et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway

(2016) Guodong Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Poly(ADP-Ribose) polymerase 1 as a key regulator of DNA repair

(2016) S. N. Khodyreva et al.   MOLECULAR BIOLOGY

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion

(2016) Yo Sasaki et al.   eLife

Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress

(2015) Natasha Jaiswal et al.   APOPTOSIS

Anti-inflammatory Effect of Ginsenoside Rb1 Contributes to the Recovery of Gastrointestinal Motility in the Rat Model of Postoperative Ileus

(2014) Shanjun Tan et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Metformin induces microRNA-34a to downregulate the Sirt1/Pgc-1α/Nrf2 pathway, leading to increased susceptibility of wild-type p53 cancer cells to oxidative stress and therapeutic agents

(2014) Minh Truong Do et al.   FREE RADICAL BIOLOGY AND MEDICINE

The sirtuin class of histone deacetylases: Regulation and roles in lipid metabolism

(2014) Erika Fiorino et al.   IUBMB LIFE

Brain distribution pharmacokinetics and integrated pharmacokinetics of Panax Notoginsenoside R1, Ginsenosides Rg1, Rb1, Re and Rd in rats after intranasal administration of Panax Notoginseng Saponins assessed by UPLC/MS/MS

(2014) Qingli Guo et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Vegetables′ juice influences polyol pathway by multiple mechanisms in favour of reducing development of oxidative stress and resultant diabetic complications

(2014) AshokK Tiwari et al.   Pharmacognosy Magazine

Identification of O-GlcNAc Modification Targets in Mouse Retinal Pericytes: Implication of p53 in Pathogenesis of Diabetic Retinopathy

(2014) Zafer Gurel et al.   PLoS One

Inputs and outputs of poly(ADP-ribosyl)ation: Relevance to oxidative stress

(2014) Csaba Hegedűs et al.   Redox Biology

Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence

(2013) Nady Braidy et al.   BIOGERONTOLOGY

Cellular NAD depletion and decline of SIRT1 activity play critical roles in PARP-1-mediated acute epileptic neuronal death in vitro

(2013) Shengjun Wang et al.   BRAIN RESEARCH

Relative Quantitative Comparison between Lipotoxicity and Glucotoxicity Affecting the PARP-NAD-SIRT1 Pathway in Hepatocytes

(2013) Jing Pang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The NAD+Synthesis Enzyme Nicotinamide Mononucleotide Adenylyltransferase (NMNAT1) Regulates Ribosomal RNA Transcription

(2013) Tanjing Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased oxidative stress in obesity: Implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer

(2013) Morihiro Matsuda et al.   Obesity Research & Clinical Practice

SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential

(2013) Munehiro Kitada et al.   Diabetes & Metabolism Journal

A compensatory mechanism protects retinal mitochondria from initial insult in diabetic retinopathy

(2012) Julia M. Santos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

(2011) Jun Yoshino et al.   Cell Metabolism

Sirt3, Mitochondrial ROS, Ageing, and Carcinogenesis

(2011) Seong-Hoon Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Poly(ADP-ribose) polymerase 1 is involved in glucose toxicity through SIRT1 modulation in HepG2 hepatocytes

(2010) Jing Pang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Enzymes in the NAD+Salvage Pathway Regulate SIRT1 Activity at Target Gene Promoters

(2009) Tong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The change of oxidative stress products in diabetes mellitus and diabetic retinopathy

(2008) H.-Z. Pan et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Ginsenoside Rb1 Preconditioning Protects Against Myocardial Infarction After Regional Ischemia and Reperfusion by Activation of Phosphatidylinositol-3-kinase Signal Transduction

(2008) Zhi Wang et al.   CARDIOVASCULAR DRUGS AND THERAPY

The ups and downs of SIRT1

(2008) Hye-Sook Kwon et al.   TRENDS IN BIOCHEMICAL SCIENCES