Poly(ADP-Ribose) polymerase 1 as a key regulator of DNA repair

Repair Pathway Choices and Consequences at the Double-Strand Break

(2016) Raphael Ceccaldi et al.   TRENDS IN CELL BIOLOGY

Processing of protein ADP-ribosylation by Nudix hydrolases

(2015) Luca Palazzo et al.   BIOCHEMICAL JOURNAL

The rise and fall of poly(ADP-ribose): An enzymatic perspective

(2015) John M. Pascal et al.   DNA REPAIR

Poly(ADP-ribose) Polymerase 1 Modulates Interaction of the Nucleotide Excision Repair Factor XPC-RAD23B with DNA via Poly(ADP-ribosyl)ation

(2015) Ekaterina A. Maltseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optimization of LTQ-Orbitrap Mass Spectrometer Parameters for the Identification of ADP-Ribosylation Sites

(2015) Florian Rosenthal et al.   JOURNAL OF PROTEOME RESEARCH

RNA Regulation by Poly(ADP-Ribose) Polymerases

(2015) Florian J. Bock et al.   MOLECULAR CELL

Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1

(2015) Sebastian Eustermann et al.   MOLECULAR CELL

Disruption of PARP1 function inhibits base excision repair of a sub-set of DNA lesions

(2015) Pamela Reynolds et al.   NUCLEIC ACIDS RESEARCH

Single molecule detection of PARP1 and PARP2 interaction with DNA strand breaks and their poly(ADP-ribosyl)ation using high-resolution AFM imaging

(2015) Maria V. Sukhanova et al.   NUCLEIC ACIDS RESEARCH

Successes and Challenges of PARP Inhibitors in Cancer Therapy

(2015) Tiffany K. Ricks et al.   Frontiers in Oncology

Chain-Terminating and Clickable NAD+Analogues for Labeling the Target Proteins of ADP-Ribosyltransferases

(2014) Yan Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Poly(ADP-ribose) polymerases in double-strand break repair: Focus on PARP1, PARP2 and PARP3

(2014) Carole Beck et al.   EXPERIMENTAL CELL RESEARCH

Phosphoproteomic Approach to Characterize Protein Mono- and Poly(ADP-ribosyl)ation Sites from Cells

(2014) Casey M. Daniels et al.   JOURNAL OF PROTEOME RESEARCH

Proteomics approaches to identify mono-(ADP-ribosyl)ated and poly(ADP-ribosyl)ated proteins

(2014) Christina A. Vivelo et al.   PROTEOMICS

PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis

(2013) Marie-France Langelier et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The absence of Ku but not defects in classical non-homologous end-joining is required to trigger PARP1-dependent end-joining

(2013) Wael Y. Mansour et al.   DNA REPAIR

DNA repair mechanisms in dividing and non-dividing cells

(2013) Teruaki Iyama et al.   DNA REPAIR

Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

(2013) Reza Sharifi et al.   EMBO JOURNAL

Mapping PARP-1 Auto-ADP-ribosylation Sites by Liquid Chromatography–Tandem Mass Spectrometry

(2013) John D Chapman et al.   JOURNAL OF PROTEOME RESEARCH

Base excision repair in the mammalian brain: Implication for age related neurodegeneration

(2013) Peter Sykora et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Therapeutic applications of PARP inhibitors: Anticancer therapy and beyond

(2013) Nicola J. Curtin et al.   MOLECULAR ASPECTS OF MEDICINE

Poly-ADP-ribose polymerase: Machinery for nuclear processes

(2013) Colin Thomas et al.   MOLECULAR ASPECTS OF MEDICINE

Poly(ADP-ribose): PARadigms and PARadoxes

(2013) Alexander Bürkle et al.   MOLECULAR ASPECTS OF MEDICINE

PARP-1 and gene regulation: Progress and puzzles

(2013) W. Lee Kraus et al.   MOLECULAR ASPECTS OF MEDICINE

Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses

(2013) Stephanie Jungmichel et al.   MOLECULAR CELL

Site-specific characterization of the Asp- and Glu-ADP-ribosylated proteome

(2013) Yajie Zhang et al.   NATURE METHODS

Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair

(2013) M. Robu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Touching base with PARPs: moonlighting in the repair of UV lesions and double-strand breaks

(2013) Alex Pines et al.   TRENDS IN BIOCHEMICAL SCIENCES

3-Aminobenzamide protects primary human keratinocytes from UV-induced cell death by a poly(ADP-ribosyl)ation independent mechanism

(2012) Petra Lakatos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Poly(ADP-ribose) Contributes to an Association between Poly(ADP-ribose) Polymerase-1 and Xeroderma Pigmentosum Complementation Group A in Nucleotide Excision Repair

(2012) Brenee S. King et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1

(2012) Alex Pines et al.   JOURNAL OF CELL BIOLOGY

DDB2 promotes chromatin decondensation at UV-induced DNA damage

(2012) Martijn S. Luijsterburg et al.   JOURNAL OF CELL BIOLOGY

Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1

(2012) M.-F. Langelier et al.   SCIENCE

Mass spectrometry-based functional proteomics of poly(ADP-ribose) polymerase-1

(2011) Emilie Pic et al.   Expert Review of Proteomics

ADP-ribosylation of histones by ARTD1: An additional module of the histone code?

(2011) Michael O. Hottiger   FEBS LETTERS

The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger

(2011) Sebastian Eustermann et al.   JOURNAL OF MOLECULAR BIOLOGY

Induction and repair of DNA double strand breaks: The increasing spectrum of non-homologous end joining pathways

(2011) Emil Mladenov et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Differences in the kinetics of γ-H2AX fluorescence decay after exposure to low and high LET radiation

(2010) Thomas E. Schmid et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Clickable NAD Analogues for Labeling Substrate Proteins of Poly(ADP-ribose) Polymerases

(2010) Hong Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies

(2010) Wael Y. Mansour et al.   NUCLEIC ACIDS RESEARCH

Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate

(2010) C. E. Strom et al.   NUCLEIC ACIDS RESEARCH

Apurinic/apyrimidinic (AP) site recognition by the 5'-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1)

(2010) S. N. Khodyreva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry

(2010) Maxim Isabelle et al.   Proteome Science

A kinetic model of single-strand annealing for the repair of DNA double-strand breaks

(2010) R. Taleei et al.   RADIATION PROTECTION DOSIMETRY

Structural and Biophysical Studies of Human PARP-1 in Complex with Damaged DNA

(2009) Wayne Lilyestrom et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of the ADP-Ribosylation Sites in the PARP-1 Automodification Domain: Analysis and Implications

(2009) Zhihua Tao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Poly(ADP-ribose) polymerase 1 regulates activity of DNA polymerase β in long patch base excision repair

(2009) Maria Sukhanova et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites

(2009) Matthias Altmeyer et al.   NUCLEIC ACIDS RESEARCH

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

(2008) Muralidhar L Hegde et al.   CELL RESEARCH

Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation

(2008) Sandra S. Haenni et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

(2008) Jean-Philippe Gagné et al.   NUCLEIC ACIDS RESEARCH