Mitochondria-targeted therapy rescues development and quality of embryos derived from oocytes matured under oxidative stress conditions: a bovine in vitro model

Mitochondrial DNA copy number as a predictor of embryo viability

(2019) Gustavo N. Cecchino et al.   FERTILITY AND STERILITY

Mitochondria as a tool for oocyte rejuvenation

(2019) Elena Labarta et al.   FERTILITY AND STERILITY

Introduction

(2019) Richard S. Legro   FERTILITY AND STERILITY

Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging

(2019) Emre Seli et al.   FERTILITY AND STERILITY

Palmitic acid induces ceramide accumulation, mitochondrial protein hyperacetylation, and mitochondrial dysfunction in porcine oocytes†

(2018) Nobuhiko Itami et al.   BIOLOGY OF REPRODUCTION

Palmitic Acid-Induced Podocyte Apoptosis via the Reactive Oxygen Species-Dependent Mitochondrial Pathway

(2018) Ting Liu et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Comparison of antagonist mild and long agonist protocols in terms of follicular fluid total antioxidant capacity

(2018) Begum Aydogan Mathyk et al.   Taiwanese Journal of Obstetrics & Gynecology

The role of fatty acids on ICSI outcomes: a prospective cohort study

(2017) Parvaneh Mirabi et al.   Lipids in Health and Disease

Differential effects of high and low glucose concentrations during lipolysis-like conditions on bovine in vitro oocyte quality, metabolism and subsequent embryo development

(2017) J. De Bie et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Low oxygen tension increases mitochondrial membrane potential and enhances expression of antioxidant genes and implantation protein of mouse blastocyst cultured in vitro

(2017) Yun-Yi Ma et al.   Journal of Ovarian Research

Enriched endoplasmic reticulum-mitochondria interactions result in mitochondrial dysfunction and apoptosis in oocytes from obese mice

(2017) Lihong Zhao et al.   Journal of Animal Science and Biotechnology

Nonesterified Fatty Acid-Induced Endoplasmic Reticulum Stress in Cattle Cumulus Oocyte Complexes Alters Cell Metabolism and Developmental Competence1

(2016) Melanie L. Sutton-McDowall et al.   BIOLOGY OF REPRODUCTION

Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts

(2016) K. L. J Desmet et al.   BMC GENOMICS

Maternal Metabolic Syndrome Programs Mitochondrial Dysfunction via Germline Changes across Three Generations

(2016) Jessica L. Saben et al.   Cell Reports

The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients

(2016) Irene Escribano-Lopez et al.   Redox Biology

Female Obesity and Infertility

(2015) Alon Talmor et al.   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

Endoplasmic reticulum stress involved in high-fat diet and palmitic acid-induced vascular damages and fenofibrate intervention

(2015) Yunxia Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential regulation of autophagy and cell viability by ceramide species

(2015) Nichola Cruickshanks et al.   CANCER BIOLOGY & THERAPY

Mitochondrial DNA content as a viability score in human euploid embryos: less is better

(2015) Antonio Diez-Juan et al.   FERTILITY AND STERILITY

Nutrition and maternal metabolic health in relation to oocyte and embryo quality: critical views on what we learned from the dairy cow model

(2015) Jo L. M. R. Leroy et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

The effect of human follicular fluid on bovine oocyte developmental competence and embryo quality

(2015) Sara D.M. Valckx et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Mitochondrial stress: Balancing friend and foe

(2014) Eva Diana Runkel et al.   EXPERIMENTAL GERONTOLOGY

Stimulation of mitochondrial embryo metabolism by dichloroacetic acid in an aged mouse model improves embryo development and viability

(2014) Nicole O. McPherson et al.   FERTILITY AND STERILITY

Associations Between Insulin Resistance, Free Fatty Acids, and Oocyte Quality in Polycystic Ovary Syndrome During In Vitro Fertilization

(2014) Zhihong Niu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mitochondrial membrane potential in 2-cell stage embryos correlates with the success of preimplantation development

(2014) Kouji Komatsu et al.   REPRODUCTION

Fatty acid composition of the follicular fluid of normal weight, overweight and obese women undergoing assisted reproductive treatment: a descriptive cross-sectional study

(2014) Sara DM Valckx et al.   Reproductive Biology and Endocrinology

Bovine Cumulus Cells Protect Maturing Oocytes from Increased Fatty Acid Levels by Massive Intracellular Lipid Storage

(2013) H. Aardema et al.   BIOLOGY OF REPRODUCTION

IVF outcomes in obese donor oocyte recipients: a systematic review and meta-analysis

(2013) E. S. Jungheim et al.   HUMAN REPRODUCTION

Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes

(2013) Estelle Hirzel et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Metabolic profiling of human follicular fluid identifies potential biomarkers of oocyte developmental competence

(2013) A O'Gorman et al.   REPRODUCTION

Amount of maternal body fat significantly affected the quality of isolated mouse preimplantation embryos and slowed down their development

(2013) Janka Kubandová et al.   THERIOGENOLOGY

Mitochondrially targeted compounds and their impact on cellular bioenergetics

(2013) Colin Reily et al.   Redox Biology

Exposure to lipid-rich follicular fluid is associated with endoplasmic reticulum stress and impaired oocyte maturation in cumulus-oocyte complexes

(2012) Xing Yang et al.   FERTILITY AND STERILITY

High Fat Diet Induced Developmental Defects in the Mouse: Oocyte Meiotic Aneuploidy and Fetal Growth Retardation/Brain Defects

(2012) Kerri M. Luzzo et al.   PLoS One

Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights

(2012) V Van Hoeck et al.   REPRODUCTION

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

(2012) A. M. Nargund et al.   SCIENCE

Differential apoptotic staining of mammalian blastocysts based on double immunofluorescent CDX2 and active caspase-3 staining

(2011) Eline Wydooghe et al.   ANALYTICAL BIOCHEMISTRY

Oleic Acid Prevents Detrimental Effects of Saturated Fatty Acids on Bovine Oocyte Developmental Competence1

(2011) Hilde Aardema et al.   BIOLOGY OF REPRODUCTION

Associations between free fatty acids, cumulus oocyte complex morphology and ovarian function during in vitro fertilization

(2011) Emily S. Jungheim et al.   FERTILITY AND STERILITY

Metabolic syndrome and mitochondrial dysfunction: insights from preclinical studies with a mitochondrially targeted antioxidant

(2011) Tanecia Mitchell et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammatory pathways linking obesity and ovarian dysfunction

(2011) Rebecca L. Robker et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Elevated Non-Esterified Fatty Acid Concentrations during Bovine Oocyte Maturation Compromise Early Embryo Physiology

(2011) Veerle Van Hoeck et al.   PLoS One

The impact of obesity on oocytes: evidence for lipotoxicity mechanisms

(2011) Linda L.-Y. Wu et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Diet-Induced Obesity Model: Abnormal Oocytes and Persistent Growth Abnormalities in the Offspring

(2010) Emily S. Jungheim et al.   ENDOCRINOLOGY

Mitochondrial DNA transmission, replication and inheritance: a journey from the gamete through the embryo and into offspring and embryonic stem cells

(2010) J. C. St. John et al.   HUMAN REPRODUCTION UPDATE

Age related changes in mitochondrial function and new approaches to study redox regulation in mammalian oocytes in response to age or maturation conditions

(2010) U. Eichenlaub-Ritter et al.   MITOCHONDRION

Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

(2010) Natalia Igosheva et al.   PLoS One

Alterations in plasma and tissue lipids associated with obesity and metabolic syndrome

(2008) Concepción M. Aguilera et al.   CLINICAL SCIENCE