Journal
REPRODUCTION FERTILITY AND DEVELOPMENT
Volume 24, Issue 1, Pages 29-34Publisher
CSIRO PUBLISHING
DOI: 10.1071/RD11904
Keywords
endoplasmic reticulum stress; palmitate
Categories
Ask authors/readers for more resources
Obesity can have detrimental effects on pregnancy rates in natural conceptions and also in women undergoing IVF or intracytoplasmic sperm injection (ICSI). This review summarises the most recent clinical literature investigating whether obesity impacts oocyte quality and early embryo growth. In other tissues, obesity leads to lipotoxicity responses including endoplasmic reticulum stress, mitochondrial dysfunction and apoptosis. Recent reports indicate that lipotoxicity is a mechanism by which obesity may impact oocyte quality.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available