Activation of invariant natural killer T cells stimulates adipose tissue remodeling via adipocyte death and birth in obesity

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

(2018) Mauro Gaya et al.   CELL

TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype

(2018) Chaoran Li et al.   CELL

Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue

(2018) David A. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CAR T cell immunotherapy for human cancer

(2018) Carl H. June et al.   SCIENCE

Fas-L promotes the stem cell potency of adipose-derived mesenchymal cells

(2018) Inna Solodeev et al.   Cell Death & Disease

De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity

(2018) Mengle Shao et al.   Nature Communications

Regulatory Roles of Invariant Natural Killer T Cells in Adipose Tissue Inflammation: Defenders Against Obesity-Induced Metabolic Complications

(2018) Yoon Jeong Park et al.   Frontiers in Immunology

Perilipin 1 (Plin1) deficiency promotes inflammatory responses in lean adipose tissue through lipid dysregulation

(2018) Jee Hyung Sohn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNF20 Suppresses Tumorigenesis by Inhibiting the SREBP1c-PTTG1 Axis in Kidney Cancer

(2017) Jae Ho Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

(2017) Kyung Cheul Shin et al.   Nature Communications

Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis

(2017) Yu A An et al.   eLife

Anti-inflammatory Mechanisms Triggered by Apoptotic Cells during Their Clearance

(2017) Zsuzsa Szondy et al.   Frontiers in Immunology

Pdgfrβ+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice

(2016) Lavanya Vishvanath et al.   Cell Metabolism

Glucose-6-Phosphate Dehydrogenase Deficiency Improves Insulin Resistance With Reduced Adipose Tissue Inflammation in Obesity

(2016) Mira Ham et al.   DIABETES

Lipodystrophy Syndromes

(2016) Iram Hussain et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice

(2016) Masashi Satoh et al.   Scientific Reports

Lipid-Overloaded Enlarged Adipocytes Provoke Insulin Resistance Independent of Inflammation

(2015) Jong In Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity

(2015) Elise Jeffery et al.   NATURE CELL BIOLOGY

Immunological contributions to adipose tissue homeostasis

(2015) Joanna R. DiSpirito et al.   SEMINARS IN IMMUNOLOGY

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Perforin Is a Novel Immune Regulator of Obesity-Related Insulin Resistance

(2014) Xavier S. Revelo et al.   DIABETES

Macrophage HIF-2  Ameliorates Adipose Tissue Inflammation and Insulin Resistance in Obesity

(2014) S. S. Choe et al.   DIABETES

Adipose Tissue and Metabolic Alterations: Regional Differences in Fat Cell Size and Number Matter, But Differently: A Cross-Sectional Study

(2014) Mikael Rydén et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adipocyte Size Threshold Matters: Link with Risk of Type 2 Diabetes and Improved Insulin Resistance After Gastric Bypass

(2014) Aurelie Cotillard et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IL-10–producing NKT10 cells are a distinct regulatory invariant NKT cell subset

(2014) Duygu Sag et al.   JOURNAL OF CLINICAL INVESTIGATION

Crosstalk between Adipocytes and Immune Cells in Adipose Tissue Inflammation and Metabolic Dysregulation in Obesity

(2014) Jin Young Huh et al.   MOLECULES AND CELLS

Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue

(2014) Lydia Lynch et al.   NATURE IMMUNOLOGY

Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration

(2013) Yun-Hee Lee et al.   Cell Metabolism

Fas andFasLExpression in Human Adipose Tissue Is Related to Obesity, Insulin Resistance, and Type 2 Diabetes

(2013) Matthias Blüher et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis

(2013) Antonio Giordano et al.   JOURNAL OF LIPID RESEARCH

Macrophage Glucose-6-Phosphate Dehydrogenase Stimulates Proinflammatory Responses with Oxidative Stress

(2013) M. Ham et al.   MOLECULAR AND CELLULAR BIOLOGY

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

(2013) Qiong A Wang et al.   NATURE MEDICINE

In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

(2012) Yun-Hee Lee et al.   Cell Metabolism

Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

(2012) Lydia Lynch et al.   IMMUNITY

Activation of Natural Killer T Cells Promotes M2 Macrophage Polarization in Adipose Tissue and Improves Systemic Glucose Tolerance via Interleukin-4 (IL-4)/STAT6 Protein Signaling Axis in Obesity

(2012) Yewei Ji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural killer T cells in adipose tissue prevent insulin resistance

(2012) Henk S. Schipper et al.   JOURNAL OF CLINICAL INVESTIGATION

A Novel Function of Adipocytes in Lipid Antigen Presentation to iNKT Cells

(2012) J. Y. Huh et al.   MOLECULAR AND CELLULAR BIOLOGY

MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity

(2012) Christine M Kusminski et al.   NATURE MEDICINE

Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet-Induced Insulin Resistance

(2011) Y. S. Lee et al.   DIABETES

Targeted Deletion of Adipocytes by Apoptosis Leads to Adipose Tissue Recruitment of Alternatively Activated M2 Macrophages

(2011) Pamela Fischer-Posovszky et al.   ENDOCRINOLOGY

Downregulation of FLIP by cycloheximide sensitizes human fat cells to CD95-induced apoptosis

(2011) Pamela Fischer-Posovszky et al.   EXPERIMENTAL CELL RESEARCH

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Inflammation and impaired adipogenesis in hypertrophic obesity in man

(2009) Birgit Gustafson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Human CD4+invariant NKT cells are involved in antibacterial immunity againstBrucella suisthrough CD1d-dependent but CD4-independent mechanisms

(2009) Stéphanie Bessoles et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Invariant NKT cells and CD1d+cells amass in human omentum and are depleted in patients with cancer and obesity

(2009) Lydia Lynch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis

(2009) Naim Alkhouri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

(2009) Stephan Wueest et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypertrophy and/or Hyperplasia: Dynamics of Adipose Tissue Growth

(2009) Junghyo Jo et al.   PLoS Computational Biology

The Inflammatory Response to Cell Death

(2008) Kenneth L. Rock et al.   Annual Review of Pathology-Mechanisms of Disease

Identification of White Adipocyte Progenitor Cells In Vivo

(2008) Matthew S. Rodeheffer et al.   CELL

Dynamics of fat cell turnover in humans

(2008) Kirsty L. Spalding et al.   NATURE