Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis

VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications

(2016) Marius R. Robciuc et al.   Cell Metabolism

Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation

(2016) Minah Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Tie1 controls angiopoietin function in vascular remodeling and inflammation

(2016) Emilia A. Korhonen et al.   JOURNAL OF CLINICAL INVESTIGATION

Docosahexaenoic acid attenuates adipose tissue angiogenesis and insulin resistance in high fat diet-fed middle-aged mice via a sirt1-dependent mechanism

(2016) Xiaoqin Luo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Targeting adipose tissue in the treatment of obesity-associated diabetes

(2016) Christine M. Kusminski et al.   NATURE REVIEWS DRUG DISCOVERY

Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles

(2016) Yuan Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome

(2016) Richard S. Beard et al.   Nature Communications

Angiopoietin-2: a multifaceted cytokine that functions in both angiogenesis and inflammation

(2015) Alexander Scholz et al.   Annals of the New York Academy of Sciences

Adipose VEGF Links the White-to-Brown Fat Switch With Environmental, Genetic, and Pharmacological Stimuli in Male Mice

(2015) Matthew J. During et al.   ENDOCRINOLOGY

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

Immunological contributions to adipose tissue homeostasis

(2015) Joanna R. DiSpirito et al.   SEMINARS IN IMMUNOLOGY

Adiponectin promotes VEGF-A-dependent angiogenesis in human chondrosarcoma through PI3K, Akt, mTOR, and HIF-α pathway

(2015) Hsiang-Ping Lee et al.   Oncotarget

Reduction of Adipose Tissue Mass by the Angiogenesis Inhibitor ALS-L1023 from Melissa officinalis

(2015) Byung Young Park et al.   PLoS One

Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure

(2014) Kai Sun et al.   Molecular Metabolism

Angiopoietin-Like Proteins: A Comprehensive Look

(2014) Gaetano Santulli   Frontiers in Endocrinology

Angiogenesis and Vascular Functions in Modulation of Obesity, Adipose Metabolism, and Insulin Sensitivity

(2013) Yihai Cao   Cell Metabolism

Adipose Vascular Endothelial Growth Factor Regulates Metabolic Homeostasis through Angiogenesis

(2013) Hoon-Ki Sung et al.   Cell Metabolism

Angiopoietin-1 elicits pro-inflammatory responses in monocytes and differentiating macrophages

(2013) Seung Hyeok Seok et al.   MOLECULES AND CELLS

Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance

(2012) I. Elias et al.   DIABETES

Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling

(2012) Moritz Felcht et al.   JOURNAL OF CLINICAL INVESTIGATION

Lack of “immunological fitness” during fasting in metabolically challenged animals

(2012) Ingrid Wernstedt Asterholm et al.   JOURNAL OF LIPID RESEARCH

MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity

(2012) Christine M Kusminski et al.   NATURE MEDICINE

Pleiotropic effects of angiopoietin-2 deficiency do not protect mice against endotoxin-induced acute kidney injury

(2012) Neng F. Kurniati et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Dichotomous effects of VEGF-A on adipose tissue dysfunction

(2012) K. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiopoietin-2 promotes myeloid cell infiltration in a  2-integrin-dependent manner

(2011) A. Scholz et al.   BLOOD

Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice

(2011) Zoi Michailidou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Angiopoietin 2 Stimulates TIE2-Expressing Monocytes To Suppress T Cell Activation and To Promote Regulatory T Cell Expansion

(2011) Seth B. Coffelt et al.   JOURNAL OF IMMUNOLOGY

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases

(2010) Yihai Cao   NATURE REVIEWS DRUG DISCOVERY

The role of the Angiopoietins in vascular morphogenesis

(2009) Markus Thomas et al.   ANGIOGENESIS

FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue

(2008) Y. Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA