DNA hypermethylation is associated with invasive phenotype of malignant melanoma

Overexpression of Tripartite Motif Conaining 55 (TRIM55) Inhibits Migration and Invasion of Hepatocellular Carcinoma (HCC) Cells via Epithelial-Mesenchymal Transition and Matrix Metalloproteinase-2 (MMP2)

(2019) Xinyu Li et al.   MEDICAL SCIENCE MONITOR

NAV2 facilitates invasion of cutaneous melanoma cells by targeting SNAI2 through the GSK-3β/β-catenin pathway

(2019) Wei Hu et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

IntEREst: intron-exon retention estimator

(2018) Ali Oghabian et al.   BMC BIOINFORMATICS

Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma

(2018) Melanie Werner-Klein et al.   Nature Communications

Adipokine RBP4 drives ovarian cancer cell migration

(2018) Yanyan Wang et al.   Journal of Ovarian Research

Promoter methylation as biomarkers for diagnosis of melanoma: A systematic review and meta-analysis

(2018) Yu Guo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

EVI1 expression is associated with aggressive behavior in intrahepatic cholangiocarcinoma

(2018) Mariko Tanaka et al.   VIRCHOWS ARCHIV

Epigenetic profiling for the molecular classification of metastatic brain tumors

(2018) Javier I. J. Orozco et al.   Nature Communications

Lowly methylated region analysis identifies EBF1 as a potential epigenetic modifier in breast cancer

(2017) Nora Fernandez-Jimenez et al.   Epigenetics

Genetic variants in the genes encoding rho GTPases and related regulators predict cutaneous melanoma-specific survival

(2017) Shun Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Functional expression of calcium-permeable canonical transient receptor potential 4-containing channels promotes migration of medulloblastoma cells

(2017) Wei-Chun Wei et al.   JOURNAL OF PHYSIOLOGY-LONDON

Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities

(2017) Goran Micevic et al.   Clinical Epigenetics

Methylation status of homeobox genes in common human cancers

(2016) Maria Fernanda Setúbal Destro Rodrigues et al.   GENOMICS

Consensus of Melanoma Gene Expression Subtypes Converges on Biological Entities

(2016) Martin Lauss et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6 ) in breast cancer

(2016) Gabriele Corda et al.   JOURNAL OF PATHOLOGY

Validation of Novel Biomarkers for Prostate Cancer Progression by the Combination of Bioinformatics, Clinical and Functional Studies

(2016) Saeid Alinezhad et al.   PLoS One

Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis

(2016) Aniruddha Chatterjee et al.   Oncotarget

Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer

(2016) Yuanhui Jia et al.   Cell Discovery

A Novel Role for Microphthalmia-Associated Transcription Factor–Regulated Pigment Epithelium-Derived Factor during Melanoma Progression

(2015) Soheil S. Dadras et al.   AMERICAN JOURNAL OF PATHOLOGY

coMET: visualisation of regional epigenome-wide association scan results and DNA co-methylation patterns

(2015) Tiphaine C Martin et al.   BMC BIOINFORMATICS

DNA methylation subgroups in melanoma are associated with proliferative and immunological processes

(2015) Martin Lauss et al.   BMC Medical Genomics

Genomic Classification of Cutaneous Melanoma

(2015) Rehan Akbani et al.   CELL

Epigenetic regulation in human melanoma: past and future

(2015) Debina Sarkar et al.   Epigenetics

The DNA methylation landscape of human melanoma

(2015) Seung-Gi Jin et al.   GENOMICS

Neuron navigator 2 overexpression indicates poor prognosis of colorectal cancer and promotes invasion through the SSH1L/cofilin-1 pathway

(2015) Fengbo Tan et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation

(2015) Martin Lauss et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Epigenetic Changes of EGFR Have an Important Role in BRAF Inhibitor–Resistant Cutaneous Melanomas

(2015) Jinhua Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data

(2015) Antonio Colaprico et al.   NUCLEIC ACIDS RESEARCH

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

(2015) Annelien Verfaillie et al.   Nature Communications

DNA Methylation Levels of Melanoma Risk Genes Are Associated with Clinical Characteristics of Melanoma Patients

(2015) Érica S. S. de Araújo et al.   Biomed Research International

Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma

(2015) Phil F Cheng et al.   GENOME BIOLOGY

Trophoblast glycoprotein promotes pancreatic ductal adenocarcinoma cell metastasis through Wnt/planar cell polarity signaling

(2015) PING HE et al.   Molecular Medicine Reports

The MAPK pathway as an apoptosis enhancer in melanoma

(2015) Johannes M. Haydn et al.   Oncotarget

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

The metabolite 5′-methylthioadenosine signals through the adenosine receptor A2B in melanoma

(2014) Katharina Limm et al.   EUROPEAN JOURNAL OF CANCER

MGMT promoter methylation is associated with temozolomide response and prolonged progression-free survival in disseminated cutaneous melanoma

(2014) Rainer Tuominen et al.   INTERNATIONAL JOURNAL OF CANCER

DNA Methylation Characteristics of Primary Melanomas with Distinct Biological Behaviour

(2014) Szilvia Ecsedi et al.   PLoS One

A data-driven approach to preprocessing Illumina 450K methylation array data

(2013) Ruth Pidsley et al.   BMC GENOMICS

Epigenetic silencing ofCHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages

(2013) Mehrnaz Fatemi et al.   CANCER

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis

(2013) Diego M. Marzese et al.   HUMAN MOLECULAR GENETICS

Methylated Tissue Factor Pathway Inhibitor 2 (TFPI2) DNA in Serum Is a Biomarker of Metastatic Melanoma

(2013) Cristiana Lo Nigro et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hippo: Hungry, Hungry for Melanoma Invasion

(2013) Ileine M. Sanchez et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Pro-Invasive Activity of the Hippo Pathway Effectors YAP and TAZ in Cutaneous Melanoma

(2013) Flore Nallet-Staub et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

(2012) Andrew E. Teschendorff et al.   BIOINFORMATICS

Melanoma revives an embryonic migration program to promote plasticity and invasion

(2012) Caleb M. Bailey et al.   Pigment Cell & Melanoma Research

Emerging molecular targets in melanoma invasion and metastasis

(2012) Jose L. Orgaz et al.   Pigment Cell & Melanoma Research

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

High density DNA methylation array with single CpG site resolution

(2011) Marina Bibikova et al.   GENOMICS

Initial steps of metastasis: Cell invasion and endothelial transmigration

(2011) Franziska van Zijl et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Epidermal growth factor receptor (EGFR) and squamous cell carcinoma of the skin: Molecular bases for EGFR-targeted therapy

(2011) Pablo Uribe et al.   PATHOLOGY RESEARCH AND PRACTICE

DNA-methylation profiling distinguishes malignant melanomas from benign nevi

(2011) Kathleen Conway et al.   Pigment Cell & Melanoma Research

Differential Expression of CHL1 Gene during Development of Major Human Cancers

(2011) Vera N. Senchenko et al.   PLoS One

Cross-Platform Array Screening Identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as Genes Frequently Silenced by Methylation in Melanoma

(2011) Vanessa F. Bonazzi et al.   PLoS One

DNA methylation biomarkers for lung cancer

(2011) Tibor A. Rauch et al.   TUMOR BIOLOGY

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Prediction of Stage, Grade, and Survival in Bladder Cancer Using Genome-wide Expression Data: A Validation Study

(2010) M. Lauss et al.   CLINICAL CANCER RESEARCH

Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies

(2010) Luca Sigalotti et al.   Journal of Translational Medicine

Navigating the cell

(2010) Eve G. Stringham et al.   Cell Adhesion & Migration

The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells

(2009) K. Paňková et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genome-wide screen of promoter methylation identifies novel markers in melanoma

(2009) Y. Koga et al.   GENOME RESEARCH

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL