Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma

A new live-cell biobank workflow efficiently recovers heterogeneous melanoma cells from native biopsies

(2015) Marieke I. G. Raaijmakers et al.   EXPERIMENTAL DERMATOLOGY

Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma

(2015) Olga Shakhova et al.   PLoS Genetics

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

SOX9: a stem cell transcriptional regulator of secreted niche signaling factors

(2014) M. Kadaja et al.   GENES & DEVELOPMENT

Hypoxia Contributes to Melanoma Heterogeneity by Triggering HIF1α-Dependent Phenotype Switching

(2013) Daniel S. Widmer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The T-box transcription factor, TBX3, is sufficient to promote melanoma formation and invasion

(2013) Jade Peres et al.   Molecular Cancer

Signaling by Fyn-ADAP via the Carma1–Bcl-10–MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells

(2013) Kamalakannan Rajasekaran et al.   NATURE IMMUNOLOGY

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

(2013) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma

(2012) Christine Guo Lian et al.   CELL

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

Systematic classification of melanoma cells by phenotype-specific gene expression mapping

(2012) Daniel S. Widmer et al.   Pigment Cell & Melanoma Research

Tumor Cell Plasticity and Angiogenesis in Human Melanomas

(2012) Daniela Mihic-Probst et al.   PLoS One

Use of Gene Expression and Pathway Signatures to Characterize the Complexity of Human Melanoma

(2011) Jennifer A. Freedman et al.   AMERICAN JOURNAL OF PATHOLOGY

Epigenetic reprogramming as a key contributor to melanocyte malignant transformation

(2011) Fernanda Molognoni et al.   Epigenetics

Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma

(2011) Tung Nguyen et al.   Epigenetics

Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo

(2011) Oscar Alcazar et al.   INTERNATIONAL JOURNAL OF CANCER

Treatment implications of the emerging molecular classification system for melanoma

(2011) Emanuela Romano et al.   LANCET ONCOLOGY

Increased methylation variation in epigenetic domains across cancer types

(2011) Kasper Daniel Hansen et al.   NATURE GENETICS

Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny

(2011) Y Cheli et al.   ONCOGENE

DNA-methylation profiling distinguishes malignant melanomas from benign nevi

(2011) Kathleen Conway et al.   Pigment Cell & Melanoma Research

Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching

(2011) Ossia M. Eichhoff et al.   Pigment Cell & Melanoma Research

Cross-Platform Array Screening Identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as Genes Frequently Silenced by Methylation in Melanoma

(2011) Vanessa F. Bonazzi et al.   PLoS One

Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized

(2010) Elsa Quintana et al.   CANCER CELL

A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

(2010) Alexander Roesch et al.   CELL

Heterogeneous Phenotype of Human Melanoma Cells with In Vitro and In Vivo Features of Tumor-Initiating Cells

(2010) Michela Perego et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The immunohistochemistry of invasive and proliferative phenotype switching in melanoma: a case report

(2010) Ossia M. Eichhoff et al.   MELANOMA RESEARCH

Aberrant DNA methylation in malignant melanoma

(2010) Carolina Schinke et al.   MELANOMA RESEARCH

Cancer stem cells versus phenotype-switching in melanoma

(2010) Keith S. Hoek et al.   Pigment Cell & Melanoma Research

A proliferative melanoma cell phenotype is responsive to RAF/MEK inhibition independent of BRAF mutation status

(2010) Marie C. Zipser et al.   Pigment Cell & Melanoma Research

Epidemiology of invasive cutaneous melanoma

(2009) R. M. MacKie et al.   ANNALS OF ONCOLOGY

An essential role for DNA methyltransferase 3a in melanoma tumorigenesis

(2009) Tao Deng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genome-wide screen of promoter methylation identifies novel markers in melanoma

(2009) Y. Koga et al.   GENOME RESEARCH

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

Tbx3 Represses E-Cadherin Expression and Enhances Melanoma Invasiveness

(2008) M. Rodriguez et al.   CANCER RESEARCH

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

(2008) J. Goodall et al.   CANCER RESEARCH

Melanoma epidemiology and trends

(2008) Claus Garbe et al.   CLINICS IN DERMATOLOGY