Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions
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Title
Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions
Authors
Keywords
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Journal
EPILEPSIA
Volume 60, Issue 11, Pages 2224-2234
Publisher
Wiley
Online
2019-10-18
DOI
10.1111/epi.16355
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Note: Only part of the references are listed.- Epidiolex (Cannabidiol): A New Hope for Patients With Dravet or Lennox-Gastaut Syndromes
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- (2018) Elizabeth A Thiele et al. LANCET
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- (2018) Orrin Devinsky et al. NEUROLOGY
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- (2018) Orrin Devinsky et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2017) T. Bakas et al. PHARMACOLOGICAL RESEARCH
- Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome
- (2017) Joshua S. Kaplan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Screening of conventional anticonvulsants in a genetic mouse model of epilepsy
- (2017) Nicole A. Hawkins et al. Annals of Clinical and Translational Neurology
- Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol
- (2016) Reesha R. Patel et al. BRAIN
- Efficacy of antiepileptic drugs for the treatment of Dravet syndrome with different genotypes
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- Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome
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- Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
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- (2008) Takayuki Seo et al. PHARMACOGENOMICS
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- (2007) E Ryberg et al. BRITISH JOURNAL OF PHARMACOLOGY
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