Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning

Melatonin in Alzheimer’s Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer’s Neuropathology

(2019) Md. Farhad Hossain et al.   MOLECULAR NEUROBIOLOGY

NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer's Therapy

(2019) Md. Tanvir Kabir et al.   CURRENT PHARMACEUTICAL DESIGN

Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease

(2019) Md. Sahab Uddin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Memantine for the Treatment of Dementia: A Review on its Current and Future Applications

(2018) Jaume Folch et al.   JOURNAL OF ALZHEIMERS DISEASE

APOE and Alzheimer’s Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer’s Pathogenesis

(2018) Md. Sahab Uddin et al.   MOLECULAR NEUROBIOLOGY

Medication compliance in Singaporean patients with Alzheimer’s disease

(2018) ZK Lum et al.   SINGAPORE MEDICAL JOURNAL

Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications

(2018) Md. Sahab Uddin et al.   Frontiers in Aging Neuroscience

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease

(2018) Fuyuki Kametani et al.   Frontiers in Neuroscience

Analyzing the chance of developing dementia among geriatric people: a cross-sectional pilot study in Bangladesh

(2018) Md. Sahab Uddin et al.   Psychogeriatrics

Autophagic dysfunction in Alzheimer’s disease: Cellular and molecular mechanistic approaches to halt Alzheimer’s pathogenesis

(2018) Md. Sahab Uddin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology

(2018) Md. Sahab Uddin et al.   MOLECULAR NEUROBIOLOGY

Discontinuation, Efficacy, and Safety of Cholinesterase Inhibitors for Alzheimer’s Disease: a Meta-Analysis and Meta-Regression of 43 Randomized Clinical Trials Enrolling 16 106 Patients

(2017) Lídia Blanco-Silvente et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Defining the earliest pathological changes of Alzheimer's disease

(2016) James C. Vickers et al.   Current Alzheimer Research

Recent progress in repositioning Alzheimer's disease drugs based on a multitarget strategy

(2016) M Amélia Santos et al.   Future Medicinal Chemistry

Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association

(2016) Costantino Iadecola et al.   HYPERTENSION

The comparative efficacy and safety of cholinesterase inhibitors in patients with mild-to-moderate Alzheimer's disease: a Bayesian network meta-analysis

(2015) Hisanori Kobayashi et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Combination Therapy with Cholinesterase Inhibitors and Memantine for Alzheimer’s Disease: A Systematic Review and Meta-Analysis

(2015) Shinji Matsunaga et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Updating stored memory requires adult hippocampal neurogenesis

(2015) Irene Suárez-Pereira et al.   Scientific Reports

Galantamine-based Hybrid Molecules with Acetylcholinesterase, Butyrylcholinesterase and γ-Secretase Inhibition Activities

(2014) L. Vezenkov et al.   Current Alzheimer Research

Design and synthesis of tacrine-phenothiazine hybrids as multitarget drugs for Alzheimer’s disease

(2014) Ai-ling Hui et al.   MEDICINAL CHEMISTRY RESEARCH

Tacrine-Flurbiprofen Hybrids as Multifunctional Drug Candidates for the Treatment of Alzheimer's Disease

(2013) Yao Chen et al.   ARCHIV DER PHARMAZIE

Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

(2013) Mirjana B. Colovic et al.   Current Neuropharmacology

Treatment of Dementia With Lewy Bodies

(2013) Brendon P. Boot et al.   Current Treatment Options in Neurology

Shifting from the single to the multitarget paradigm in drug discovery

(2013) José L. Medina-Franco et al.   DRUG DISCOVERY TODAY

A novel series of tacrine–selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease

(2013) Chuanjun Lu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Somatic comorbidities and Alzheimer’s disease treatment

(2013) Alessandra Clodomiro et al.   NEUROLOGICAL SCIENCES

Alzheimer disease in the United States (2010-2050) estimated using the 2010 census

(2013) L. E. Hebert et al.   NEUROLOGY

Memantine and Cholinesterase Inhibitors: Complementary Mechanisms in the Treatment of Alzheimer’s Disease

(2013) Chris G. Parsons et al.   NEUROTOXICITY RESEARCH

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Benefits of combined cholinesterase inhibitor and memantine treatment in moderate–severe Alzheimer's disease

(2012) Serge Gauthier et al.   Alzheimers & Dementia

Design, synthesis, and evaluation of indanone derivatives as acetylcholinesterase inhibitors and metal-chelating agents

(2012) Fan-Chao Meng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Propargylamine-derived multitarget-directed ligands: fighting Alzheimer’s disease with monoamine oxidase inhibitors

(2012) Irene Bolea et al.   JOURNAL OF NEURAL TRANSMISSION

Cholinergic imbalance in the multiple sclerosis hippocampus

(2011) Evert-Jan Kooi et al.   ACTA NEUROPATHOLOGICA

Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil andN-[(5-(Benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

(2011) Irene Bolea et al.   JOURNAL OF MEDICINAL CHEMISTRY

The projected effect of risk factor reduction on Alzheimer's disease prevalence

(2011) Deborah E Barnes et al.   LANCET NEUROLOGY

Tacrine-mefenamic acid hybrids for inhibition of acetylcholinesterase

(2011) Joshua J. Bornstein et al.   MedChemComm

Interactions of AChE with A? Aggregates in Alzheimer?s Brain: Therapeutic Relevance of IDN 5706

(2011) Francisco J. Carvajal et al.   Frontiers in Molecular Neuroscience

Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease

(2010) N. R. Cutler et al.   ACTA NEUROLOGICA SCANDINAVICA

Adding Delayed Recall to the Alzheimer Disease Assessment Scale is Useful in Studies of Mild Cognitive Impairment But Not Alzheimer Disease

(2010) Mary Sano et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Predictors of adherence among Alzheimer's disease patients receiving oral therapy

(2010) Bijan Borah et al.   CURRENT MEDICAL RESEARCH AND OPINION

Effects of Cholinesterase Inhibitors on Visual Attention in Drivers With Alzheimer Disease

(2010) Lori A. Daiello et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

(2010) John C O'Leary et al.   Molecular Neurodegeneration

Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and β-secretase

(2009) Yiping Zhu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and evaluation of galanthamine derivatives as acetylcholinesterase inhibitors

(2008) Ping Jia et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY