Proline‐Rich Peptides with Improved Antimicrobial Activity against E. coli , K. pneumoniae , and A. baumannii

Search for Shorter Portions of the Proline-Rich Antimicrobial Peptide Fragment Bac5(1-25) That Retain Antimicrobial Activity by Blocking Protein Synthesis

(2019) Mario Mardirossian et al.   ChemMedChem

Fragments of the non-lytic proline-rich antimicrobial peptide Bac5 kill E. coli cells by inhibiting protein synthesis.

(2018) Mario Mardirossian et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Proline-rich antimicrobial peptides targeting protein synthesis

(2017) Michael Graf et al.   NATURAL PRODUCT REPORTS

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

(2017) Tanja Florin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

(2017) Tanja Florin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Screening and Optimizing Antimicrobial Peptides by Using SPOT-Synthesis

(2017) Paula M. López-Pérez et al.   Frontiers in Chemistry

In vivo target exploration of apidaecin based on Acquired Resistance induced by Gene Overexpression (ARGO assay)

(2017) Ken’ichiro Matsumoto et al.   Scientific Reports

Pyrrhocoricin, a proline-rich antimicrobial peptide derived from insect, inhibits the translation process in the cell-free Escherichia coli protein synthesis system

(2016) Masayuki Taniguchi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition

(2016) Matthieu G. Gagnon et al.   NUCLEIC ACIDS RESEARCH

Structure of the mammalian antimicrobial peptide Bac7(1–16) bound within the exit tunnel of a bacterial ribosome

(2016) A. Carolin Seefeldt et al.   NUCLEIC ACIDS RESEARCH

Antimicrobial Peptides: An Emerging Category of Therapeutic Agents

(2016) Margit Mahlapuu et al.   Frontiers in Cellular and Infection Microbiology

Optimization of oncocin for antibacterial activity using a SPOT synthesis approach: extending the pathogen spectrum to Staphylococcus aureus

(2015) Daniel Knappe et al.   AMINO ACIDS

Influence of theyjiL-mdtMGene Cluster on the Antibacterial Activity of Proline-Rich Antimicrobial Peptides Overcoming Escherichia coli Resistance Induced by the Missing SbmA Transporter System

(2015) Andor Krizsan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interaction of blood components with cathelicidins and their modified versions

(2015) Kai Yu et al.   BIOMATERIALS

Structure-activity relationship study using peptide arrays to optimize Api137 for an increased antimicrobial activity against Pseudomonas aeruginosa

(2015) Martina E.C. Bluhm et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex

(2015) A Carolin Seefeldt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

(2015) Raktim N Roy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex

(2015) A Carolin Seefeldt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

(2015) Raktim N Roy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Insect-Derived Proline-Rich Antimicrobial Peptides Kill Bacteria by Inhibiting Bacterial Protein Translation at the 70 S Ribosome

(2014) Andor Krizsan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Host Antimicrobial Peptide Bac71-35 Binds to Bacterial Ribosomal Proteins and Inhibits Protein Synthesis

(2014) Mario Mardirossian et al.   CHEMISTRY & BIOLOGY

Antimicrobial Peptides for Therapeutic Applications: A Review

(2012) Min-Duk Seo et al.   MOLECULES

Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action

(2011) Marco Scocchi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rational Design of Oncocin Derivatives with Superior Protease Stabilities and Antibacterial Activities Based on the High-Resolution Structure of the Oncocin-DnaK Complex

(2011) Daniel Knappe et al.   CHEMBIOCHEM

Antibacterial and anti-biofilm effects of cathelicidin peptides against pathogens isolated from cystic fibrosis patients

(2011) A. Pompilio et al.   PEPTIDES

Oncocin (VDKPPYLPRPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens

(2010) Daniel Knappe et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Proline-rich Antibacterial Peptide Bac7 Binds to and Inhibits in vitro the Molecular Chaperone DnaK

(2009) Marco Scocchi et al.   International Journal of Peptide Research and Therapeutics

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols

Scope and limitations of the designer proline-rich antibacterial peptide dimer, A3-APO, alone or in synergy with conventional antibiotics

(2008) Marco Cassone et al.   PEPTIDES