Inhibition of PDE4 Attenuates TNF-α-Triggered Cell Death Through Suppressing NF-κB and JNK Activation in HT-22 Neuronal Cells
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibition of PDE4 Attenuates TNF-α-Triggered Cell Death Through Suppressing NF-κB and JNK Activation in HT-22 Neuronal Cells
Authors
Keywords
-
Journal
CELLULAR AND MOLECULAR NEUROBIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-10-29
DOI
10.1007/s10571-019-00745-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The AKT Activator SC79 Protects Hepatocytes from TNFα-mediated Apoptosis and Alleviates D-Gal/LPS-induced Liver Injury
- (2019) Zhen-Tang Jing et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- FCPR03, a novel phosphodiesterase 4 inhibitor, alleviates cerebral ischemia/reperfusion injury through activation of the AKT/GSK3β/ β-catenin signaling pathway
- (2019) Bingtian Xu et al. BIOCHEMICAL PHARMACOLOGY
- Inhibition of PDE4 by FCPR16 induces AMPK-dependent autophagy and confers neuroprotection in SH-SY5Y cells and neurons exposed to MPP+-induced oxidative insult
- (2019) Jiahong Zhong et al. FREE RADICAL BIOLOGY AND MEDICINE
- The phosphodiesterase-4 inhibitor, FCPR16, attenuates ischemia-reperfusion injury in rats subjected to middle cerebral artery occlusion and reperfusion
- (2018) Jiajia Chen et al. BRAIN RESEARCH BULLETIN
- TNF-alpha and TNF-R1 regulate bupivacaine-induced apoptosis in spinal cord dorsal root ganglion neuron
- (2018) Ke Zhang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Checkpoints in TNF-Induced Cell Death: Implications in Inflammation and Cancer
- (2018) Alessandro Annibaldi et al. TRENDS IN MOLECULAR MEDICINE
- RNA Interference-Mediated Knockdown of Long-Form Phosphodiesterase-4D (PDE4D) Enzyme Reverses Amyloid-β42-Induced Memory Deficits in Mice
- (2018) Cong Zhang et al. JOURNAL OF ALZHEIMERS DISEASE
- Microglia in neurodegeneration
- (2018) Suzanne Hickman et al. NATURE NEUROSCIENCE
- Inhibition of Phosphodiesterase 4 by FCPR03 Alleviates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors and Prevents Dendritic Spine Loss in Mice Hippocampi
- (2018) Hui Yu et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- TNF-α enhances apoptosis by promoting chop expression in nucleus pulposus cells: role of the MAPK and NF-κB pathways
- (2018) Jian Zhang et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Neutral Sphingomyelinase Inhibition Alleviates LPS Induced Microglia Activation and Neuroinflammation after Experimental Traumatic Brain Injury
- (2018) Asit Kumar et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases
- (2018) Heng Li et al. Frontiers in Pharmacology
- FCPR16, a novel phosphodiesterase 4 inhibitor, produces an antidepressant-like effect in mice exposed to chronic unpredictable mild stress
- (2018) Qiuping Zhong et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- TNFα-induced downregulation of microRNA-186 contributes to apoptosis in rat primary cardiomyocytes
- (2017) Hua Xu et al. IMMUNOBIOLOGY
- TNF-α Deficiency Prevents Renal Inflammation and Oxidative Stress in Obese Mice
- (2017) Huaiguo Wang et al. KIDNEY & BLOOD PRESSURE RESEARCH
- Blood–Brain Barrier Penetrating Biologic TNF-α Inhibitor for Alzheimer’s Disease
- (2017) Rudy Chang et al. MOLECULAR PHARMACEUTICS
- FFPM, a PDE4 inhibitor, reverses learning and memory deficits in APP/PS1 transgenic mice via cAMP/PKA/CREB signaling and anti-inflammatory effects
- (2017) Haibiao Guo et al. NEUROPHARMACOLOGY
- Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling
- (2016) Zhiqiang Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- TRAF2 multitasking in TNF receptor-induced signaling to NF-κB, MAP kinases and cell death
- (2016) Alice Borghi et al. BIOCHEMICAL PHARMACOLOGY
- Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia via the TRAF-Interacting Protein TIFA
- (2016) Tong-You Wade Wei et al. CANCER RESEARCH
- Enhancing cAMP Levels as Strategy for the Treatment of Neuropsychiatric Disorders
- (2016) Ana M. Garcia et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Development of highly potent phosphodiesterase 4 inhibitors with anti-neuroinflammation potential: Design, synthesis, and structure-activity relationship study of catecholamides bearing aromatic rings
- (2016) Zhong-Zhen Zhou et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The protective or damaging effect of Tumor necrosis factor-α in acute liver injury is concentration-dependent
- (2016) Yulong Dong et al. Cell and Bioscience
- TNF biology, pathogenic mechanisms and emerging therapeutic strategies
- (2015) George D. Kalliolias et al. Nature Reviews Rheumatology
- Allicin protects spinal cord neurons from glutamate-induced oxidative stress through regulating the heat shock protein 70/inducible nitric oxide synthase pathway
- (2015) Shu-Guang Liu et al. Food & Function
- Paeoniflorin protects cells from GalN/TNF-α-induced apoptosis via ER stress and mitochondria-dependent pathways in human L02 hepatocytes
- (2014) Zequn Jiang et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- cAMP-specific phosphodiesterase inhibitors: promising drugs for inflammatory and neurological diseases
- (2014) Ana Martinez et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- TRIM38 inhibits TNF - and IL-1 -triggered NF- B activation by mediating lysosome-dependent degradation of TAB2/3
- (2014) M.-M. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clinical targeting of the TNF and TNFR superfamilies
- (2013) Michael Croft et al. NATURE REVIEWS DRUG DISCOVERY
- Isomenthone protects human dermal fibroblasts from TNF-α-induced death possibly by preventing activation of JNK and p38 MAPK
- (2012) Eunsun Jung et al. FOOD AND CHEMICAL TOXICOLOGY
- TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation
- (2012) Karim Belarbi et al. Journal of Neuroinflammation
- Targeting TNF-Alpha to Elucidate and Ameliorate Neuroinflammation in Neurodegenerative Diseases
- (2011) Kathryn A. Frankola et al. CNS & Neurological Disorders-Drug Targets
- Glutamate released by Japanese encephalitis virus-infected microglia involves TNF-α signaling and contributes to neuronal death
- (2011) Chun-Jung Chen et al. GLIA
- A Meta-Analysis of Cytokines in Alzheimer's Disease
- (2010) Walter Swardfager et al. BIOLOGICAL PSYCHIATRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More