Cholesterol depletion sensitizes gallbladder cancer to cisplatin by impairing DNA damage response

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

(2019) Esperanza Perucha et al.   Nature Communications

Targeting the mevalonate pathway to overcome acquired anti-HER2 treatment resistance in breast cancer

(2019) Vidyalakshmi Sethunath et al.   MOLECULAR CANCER RESEARCH

p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression

(2018) Sung-Hwan Moon et al.   CELL

Statin use and reduced risk of biliary tract cancers in the UK Clinical Practice Research Datalink

(2018) Zhiwei Liu et al.   GUT

Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex

(2017) Brian M. Castellano et al.   SCIENCE

Predictors of incidental gallbladder cancer in patients undergoing cholecystectomy for benign gallbladder disease: Results from a population-based gallstone surgery registry

(2017) Carolina Muszynska et al.   SURGERY

The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

(2017) Amy E. Baek et al.   Nature Communications

The Timing of Reoperation for Incidental Gallbladder Cancer

(2017) Vatche G. Agopian et al.   JAMA Surgery

PI3K/AKT/mTOR: role in breast cancer progression, drug resistance, and treatment

(2016) Angel Guerrero-Zotano et al.   CANCER AND METASTASIS REVIEWS

Cholesterol Metabolism and Prostate Cancer Lethality

(2016) K. H. Stopsack et al.   CANCER RESEARCH

Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection

(2016) Xin Gong et al.   CELL

Hippocalcin-like 1 suppresses hepatocellular carcinoma progression by promoting p21Waf/Cip1 stabilization by activating the ERK1/2-MAPK pathway

(2016) Yonglong Zhang et al.   HEPATOLOGY

Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism

(2016) Nora Kory et al.   JOURNAL OF LIPID RESEARCH

NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer

(2016) Rajendra Karki et al.   NATURE

Statins for primary prevention of cardiovascular disease

(2016) Catherine M Otto   BMJ-British Medical Journal

Statins for primary prevention of cardiovascular disease

(2016) Catherine M Otto   BMJ-British Medical Journal

Impact of Statin Use on Survival in Patients Undergoing Resection for Early-Stage Pancreatic Cancer

(2015) Bechien U Wu et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

MYC and metabolism on the path to cancer

(2015) Annie L. Hsieh et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Statin use is associated with lower risk of liver cancer, study shows

(2015) S. Mayor   BMJ-British Medical Journal

Statin use is associated with lower risk of liver cancer, study shows

(2015) S. Mayor   BMJ-British Medical Journal

HMG-CoA reductase inhibitors as adjuvant treatment for hematologic malignancies: what is the current evidence?

(2014) Bruno Bockorny et al.   ANNALS OF HEMATOLOGY

Statin use and risk for ovarian cancer: a Danish nationwide case–control study

(2014) L Baandrup et al.   BRITISH JOURNAL OF CANCER

Obesity, Cholesterol Metabolism, and Breast Cancer Pathogenesis

(2014) D. P. McDonnell et al.   CANCER RESEARCH

Therapeutic Reflections in Cholesterol Homeostasis and Gallstone Disease: A Review

(2014) Agostino Ciaula et al.   CURRENT MEDICINAL CHEMISTRY

Inflammatory and metabolic biomarkers and risk of liver and biliary tract cancer

(2014) Krasimira Aleksandrova et al.   HEPATOLOGY

On Estrogen, Cholesterol Metabolism, and Breast Cancer

(2014) Margaret Warner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sterols and oxysterols in immune cell function

(2013) Nathanael J Spann et al.   NATURE IMMUNOLOGY

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

(2013) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A specific cholesterol metabolic pathway is established in a subset of HCCs for tumor growth

(2013) Ming Lu et al.   Journal of Molecular Cell Biology

Cholesterol and the risk of grade-specific prostate cancer incidence: evidence from two large prospective cohort studies with up to 37 years' follow up

(2012) Kashif Shafique et al.   BMC CANCER

Plasma total, LDL, and HDL cholesterol and risk of aggressive prostate cancer in the Cancer Prevention Study II Nutrition Cohort

(2012) Eric J. Jacobs et al.   CANCER CAUSES & CONTROL

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Cholesterol and prostate cancer

(2012) Kristine Pelton et al.   CURRENT OPINION IN PHARMACOLOGY

Expression profile of cholecystokinin type-A receptor in gallbladder cancer and gallstone disease

(2012) Rajani Rai et al.   Hepatobiliary & Pancreatic Diseases International

Statin Use and Reduced Cancer-Related Mortality

(2012) Sune F. Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

CHK1 Inhibitors in Combination Chemotherapy: Thinking Beyond the Cell Cycle

(2011) P. Dent et al.   MOLECULAR INTERVENTIONS

Genetic variants involved in gallstone formation and capsaicin metabolism, and the risk of gallbladder cancer in Chilean women

(2010) Sergio Báez   WORLD JOURNAL OF GASTROENTEROLOGY

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Cellular cholesterol trafficking and compartmentalization

(2008) Elina Ikonen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

 -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

(2008) A. Kinner et al.   NUCLEIC ACIDS RESEARCH