Blood flow patterns regulate PCSK9 secretion via MyD88-mediated pro-inflammatory cytokines

PCSK9 regulates expression of scavenger receptors and ox-LDL uptake in macrophages

(2018) Zufeng Ding et al.   CARDIOVASCULAR RESEARCH

PCSK9 plays a novel immunological role in oxidized LDL-induced dendritic cell maturation and activation of T cells from human blood and atherosclerotic plaque

(2018) A. Liu et al.   JOURNAL OF INTERNAL MEDICINE

Analysis of non-Newtonian effects within an aorta-iliac bifurcation region

(2017) Marcello Iasiello et al.   JOURNAL OF BIOMECHANICS

Investigation of highly expressed PCSK9 in atherosclerotic plaques and ox-LDL-induced endothelial cell apoptosis

(2017) Jiao Li et al.   Molecular Medicine Reports

Cross-Talk Between PCSK9 and Damaged mtDNA in Vascular Smooth Muscle Cells: Role in Apoptosis

(2016) Zufeng Ding et al.   ANTIOXIDANTS & REDOX SIGNALING

Hemodynamic Shear Stress via ROS Modulates PCSK9 Expression in Human Vascular Endothelial and Smooth Muscle Cells and Along the Mouse Aorta

(2015) Zufeng Ding et al.   ANTIOXIDANTS & REDOX SIGNALING

PCSK9 inhibitors: Novel therapeutic agents for the treatment of hypercholesterolemia

(2015) Rutger Verbeek et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Physiological Significance of Helical Flow in the Arterial System and its Potential Clinical Applications

(2014) Xiao Liu et al.   ANNALS OF BIOMEDICAL ENGINEERING

Toll-Like Receptor Signaling Pathways

(2014) Takumi Kawasaki et al.   Frontiers in Immunology

Lipopolysaccharide Activates Toll-like Receptor 4 (TLR4)-mediated NF-κB Signaling Pathway and Proinflammatory Response in Human Pericytes

(2013) Irene Guijarro-Muñoz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB, Inflammation, and Metabolic Disease

(2011) Rebecca G. Baker et al.   Cell Metabolism

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Spiral systolic blood flow in the ascending aorta and aortic arch analyzed by echo-dynamography

(2010) Motonao Tanaka et al.   Journal of Cardiology

The relative atherogenicity of VLDL and LDL is dependent on the topographic site

(2010) Eline Van Craeyveld et al.   JOURNAL OF LIPID RESEARCH

TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules

(2010) N. Matsunaga et al.   MOLECULAR PHARMACOLOGY

A numerical study on the flow of blood and the transport of LDL in the human aorta: the physiological significance of the helical flow in the aortic arch

(2009) Xiao Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Three-dimensional analysis of segmental wall shear stress in the aorta by flow-sensitive four-dimensional-MRI

(2009) Alex Frydrychowicz et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING