Article
Chemistry, Applied
Yongsheng Ni, Jing Sun, Jianlong Wang
Summary: This paper presents a new strategy for developing konjac glucomannan-based antibacterial films with a broad-spectrum antibacterial activity. The films, incorporating CNMo nanocomposites, show excellent performances in terms of structural, mechanical, and thermal properties, as well as hydrophobicity, prolonging the shelf life of cherry tomatoes. Hemolysis and cells experiment confirm the safety of the film, indicating potential applications in antibacterial packaging.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Liying Huang, Huanglong Lin, Nitong Bu, Jie Pang, Ruojun Mu
Summary: In this research, PVP microfibers incorporated water-in-oil (W/O) emulsions were prepared. The W/O emulsions consisted of hexadecyl konjac glucomannan (HKGM, emulsifier), corn oil (oil phase), and purple corn anthocyanins (PCAs, water phase). The emulsions and microfibers were characterized using CLSM, SEM, FT-IR, Raman, and NMR spectroscopy. The results demonstrated that the addition of PCAs improved the water resistance, mechanical strength, antioxidation, and antibacterial activity of the microfiber films. The microfiber films also exhibited controlled release of PCAs, making them suitable for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Rixiang Su, Wei Su, Jinyun Cai, Lei Cen, Shanshan Huang, Yu Wang, Peiyuan Li
Summary: In this study, a nanocomposite drug was developed to overcome the limitations of photo-sensitizers and form composite films with improved stability and mechanical properties. The nanocomposite drug showed good biocompatibility and PDT antibacterial effects, making it a promising nano-antibacterial agent for the treatment of bacterial infections and wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Shancan Wang, Mingyu Li, Beibei He, Yueyuan Yong, Jie Zhu
Summary: Currently, food waste and the potential hazards of petroleum-based food packaging films have become serious issues, leading to increased focus on the development of new food packaging materials. In this study, a novel packaging film based on sodium alginate and konjac glucomannan blended with tea polyphenols was prepared. The film exhibited excellent microstructure, mechanical properties, barrier property, oxidation property, antibacterial activity, and stability. The results also showed that tea polyphenols could affect bacterial growth by interacting with peptidoglycan in the cell wall. Additionally, the film demonstrated excellent preservation effects in beef and apples, indicating its potential as a bioactive packaging material for food preservation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Jingting Xu, Ying Yang, Lu Liu, Xin Huang, Chunhua Wu, Jie Pang, Renhui Qiu, Shuyi Wu
Summary: In this study, bio-fibers were prepared using different channel shapes and the dynamical behaviors of macromolecule clusters in flow fields were simulated. The results show that the elongational flow with increasing extension rates produced fibers with improved tensile strength and strain. The channel shapes significantly influence flow fields, dynamical behaviors of molecule clusters, the morphology of fibers, and tensile performances.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Zhe Liu, Dehui Lin, Rui Shen, Runguang Zhang, Liu Liu, Xingbin Yang
Summary: The study developed edible films based on konjac glucomannan (KGM) loaded with different concentrations of thyme essential oil (TEO) and found that TEO distribution influenced film roughness, hydrophilic characteristics decreased with increasing TEO concentrations, and antioxidant capacities and antibacterial activities of the films improved.
FOOD PACKAGING AND SHELF LIFE
(2021)
Article
Chemistry, Applied
Shikai Zhang, Ziyang He, Fangzhou Xu, Yue Cheng, Geoffrey I. N. Waterhouse, Dongxiao Sun-Waterhouse, Peng Wu
Summary: The addition of ZPEO in KGM films can modify their properties, leading to high-performance composite films with enhanced tensile strength, water contact angle, and antibacterial properties, as well as the ability to slowly release essential oils.
FOOD HYDROCOLLOIDS
(2022)
Article
Biochemistry & Molecular Biology
Wanzhen Xie, Yu Du, Shuyi Yuan, Jie Pang
Summary: Active composite films were developed by incorporating different concentrations of dihydromyricetin (DMY) into konjac glucomannan (KGM)/gellan gum (GG) matrix. The films showed good physicochemical properties, enhanced antioxidant and antimicrobial activities, as well as promising application in food packaging.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Biochemistry & Molecular Biology
Lingling Tian, Jingyun Ma, Wei Li, Xu Zhang, Xinghua Gao
Summary: Microfibers can be formed into functional 3D structures by folding, binding, and weaving. Microfluidic spinning technology, as a novel method, can precisely control the size, morphology, structure, and composition of microfibers. It is suitable for preparing microfibers with biocompatible materials without affecting cell viability, making it ideal for tissue engineering applications.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Chemistry, Applied
Yongsheng Ni, Jingyao Wang, Jing Sun, Jianlong Wang
Summary: This study successfully developed functional KCNGO films with excellent performance, showcasing a potential application in food preservation through quasi-pasteurization strategy.
Article
Chemistry, Applied
Fei Li, Xuejiao Sun, Wen Yu, Chengcheng Shi, Xiaoyu Zhang, Hongbo Yu, Fuying Ma
Summary: The LPMO from Pleurotus ostreatus efficiently depolymerizes KGM to produce oligosaccharides, which, when used as a carbon source, significantly promote the growth of probiotic bacteria and the production of SCFAs, leading to improved gastrointestinal health.
CARBOHYDRATE POLYMERS
(2021)
Article
Nanoscience & Nanotechnology
Chuanyi Gu, Chunru Wang, Wenjie Ma, Yunli Gao, Junyao Li, Qing Jin, Xiaochen Wu
Summary: To address the serious threat of bacterial infections to human health, it is crucial to enhance the antibacterial capability of tissue engineering matrices. The loading of antibacterial drugs onto nanomaterials provides an efficient approach for achieving synergistic antibacterial effects, leading to the development of antibacterial hydrogels with high drug loading capacities and sustained drug release. These hydrogels show great potential as three-dimensional substrates for biomedical applications, including tissue engineering and regenerative medicine.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Materials Science, Paper & Wood
Zhen Yuan, Junwen Cheng, Guangqian Lan, Fei Lu
Summary: Antibacterial and moisturizing dressings were fabricated using cellulose/konjac glucomannan/Ag nanoparticle composites, with properties easily manipulated by adjusting composition ratios. The CK7-Ag3 aerogel showed excellent antibacterial activity and biocompatibility, enabling complete wound recovery within just 14 days.
Article
Food Science & Technology
Jingya Song, Jingjing Zhou, Xiang Li, Peilin Li, Guozheng Tian, Chi Zhang, Dazhai Zhou
Summary: By introducing konjac glucomannan as a stabilizer, this study successfully prepared KGM-SeNPs with high biological activity and low toxicity, optimized reaction parameters, and demonstrated potential applications in food and pharmaceutical products.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Applied
Wanli Zhang, Jong-Whan Rhim
Summary: Konjac glucomannan (KGM), a safe and edible polysaccharide substance, can be converted into active food packaging films. However, the pure KGM-based film lacks mechanical properties and gas barrier properties due to its strong hydrophilicity, so strategies are needed to improve its performance.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Applied
Chunhua Wu, Jishuai Sun, Pingyun Zheng, Xuan Kang, Meiyu Chen, Yuanzhao Li, Yujun Ge, Yaqin Hu, Jie Pang
CARBOHYDRATE POLYMERS
(2019)
Article
Food Science & Technology
Lin Wang, Ruo-Jun Mu, Yuanzhao Li, Lizhuan Lin, Zheya Lin, Jie Pang
LWT-FOOD SCIENCE AND TECHNOLOGY
(2019)
Article
Chemistry, Applied
Lin Wang, Yuanzhao Li, Lizhun Lin, Ruojun Mu, Jie Pang
CARBOHYDRATE POLYMERS
(2020)
Article
Biochemistry & Molecular Biology
Wanmei Lin, Yongsheng Ni, Jie Pang
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Engineering, Environmental
Yongsheng Ni, Rong Wang, Wentao Zhang, Shuo Shi, Wenxin Zhu, Manshun Liu, Chengyuan Yang, Xianghong Xie, Jianlong Wang
Summary: Photodynamic inactivation using graphitic carbon nitride (g-C3N4) has been widely researched for sterilization, with nanostructured materials showing great potential in enhancing its efficacy. This review systematically analyzed studies on g-C3N4-based nanostructured materials, discussing strategies, light sources, targeted organisms, and future perspectives.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Physical
Liang Zhang, Jing Wang, Huiting Wang, Wentao Zhang, Wenxin Zhu, Ting Du, Yongsheng Ni, Xianghong Xie, Jing Sun, Jianlong Wang
Summary: This study successfully constructed a smart adsorbent NSU66 with mixed-ligand and hierarchical-pore structure using the SALE approach, which can simultaneously sense and remove Hg2+ in water with high efficiency. NSU66 shows significant improvements in sensing and trapping capabilities compared to NU66, indicating promising application prospects.
Article
Chemistry, Applied
Yongsheng Ni, Jing Sun, Jianlong Wang
Summary: This paper presents a new strategy for developing konjac glucomannan-based antibacterial films with a broad-spectrum antibacterial activity. The films, incorporating CNMo nanocomposites, show excellent performances in terms of structural, mechanical, and thermal properties, as well as hydrophobicity, prolonging the shelf life of cherry tomatoes. Hemolysis and cells experiment confirm the safety of the film, indicating potential applications in antibacterial packaging.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Physical
Xianghong Xie, Rong Wang, Xixi Zhang, Yarong Ren, Ting Du, Yongsheng Ni, Huiling Yan, Liang Zhang, Jing Sun, Wentao Zhang, Jianlong Wang
Summary: The synergistic antibacterial strategy presented in this study utilizes copper peroxide and tungsten disulfide nanoflowers to activate the Fenton reaction under acidic conditions and eliminate bacteria by transforming light into localized heat under near-infrared laser irradiation. This system has shown significant antibacterial effects on Escherichia coli and Staphylococcus aureus both in vitro and in vivo, suggesting its potential for rational design of synergistic antibacterial systems.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2021)
Article
Chemistry, Applied
Yongsheng Ni, Shuo Shi, Min Li, Liang Zhang, Chengyuan Yang, Ting Du, Shaochi Wang, Hongqing Nie, Jing Sun, Wentao Zhang, Jianlong Wang
Summary: The research focuses on a new type of low-cost, less-loss and adjustable sustained antibacterial activity food packaging films with self-activation ability and great industrialization potential. The novel chitosan/negatively charged graphitic carbon nitride self-activation bionanocomposite films show high antibacterial efficiency and can extend shelf life of tangerines, while being safe and nontoxic.
Review
Polymer Science
Ning Zhou, Shengxuan Zheng, Wanzhen Xie, Guoyu Cao, Lin Wang, Jie Pang
Summary: Recently, natural bio-based materials like Konjac glucomannan (KGM) have shown great potential in wound dressings due to their water retention, biocompatibility, and therapeutic properties. By combining KGM with other polymers, the mechanical properties can be improved to promote wound healing.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Engineering, Environmental
Yongsheng Ni, Jingyao Wang, Mengyi Wang, Lizhi Liu, Hongqing Nie, Qiaoling Wang, Jing Sun, Tianli Yue, Ming-Qiang Zhu, Jianlong Wang
Summary: Inspired by COVID-19, researchers designed an artificial virus with coronal morphology that showed promising results in sterilization and wound healing.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Food Science & Technology
Mile Li, Mengyi Wang, Shuhui Hu, Jing Sun, Mingqiang Zhu, Yongsheng Ni, Jianlong Wang
Summary: A new active coating, based on konjac glucomannan, was developed, which exhibited excellent antioxidant activity and could effectively inhibit the growth of bacteria, thereby prolonging the shelf life of kumquat.
Review
Food Science & Technology
Yuechun Li, Jing Sun, Lunjie Huang, Sijie Liu, Shaochi Wang, Daohong Zhang, Mingqiang Zhu, Jianlong Wang
Summary: With the rapid growth in global food production, delivery, and consumption, reformative food analytical techniques are required to satisfy the monitoring requirements of speed and high sensitivity. Nanozyme-encoded luminescent detections (NLDs) integrating nanozyme-based rapid detections with luminescent output signals have emerged as powerful methods for food safety monitoring, not only because of their preeminent performance in analysis, such as rapid, facile, low background signal, and ultrasensitive, but also due to their strong attractiveness for future sensing research.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2022)
Article
Chemistry, Applied
Wenze Wang, Liang Zhang, Puyuan Hu, Yuxuan Wang, Xinyi Jin, Rui Chen, Wentao Zhang, Yongsheng Ni, Jianlong Wang
Summary: A novel packaging film was developed to tackle microbial contamination and spoilage during pork storage by incorporating shellac-encapsulated cinnamaldehyde nano-capsules (SNCs) and chitosan (CS) film matrix. The film demonstrated controlled release behavior and antimicrobial properties, effectively extending the freshness duration of pork and regulating environmental moisture.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
