Augmentation of NAD+ by NQO1 attenuates cisplatin-mediated hearing impairment

A Mutually Inhibitory Feedback Loop between the 20S Proteasome and Its Regulator, NQO1

(2015) Oren Moscovitz et al.   MOLECULAR CELL

Pharmacological activation of NQO1 increases NAD+ levels and attenuates cisplatin-mediated acute kidney injury in mice

(2013) Gi-Su Oh et al.   KIDNEY INTERNATIONAL

Protective role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in cisplatin-induced nephrotoxicity

(2013) Gil-Tae Gang et al.   TOXICOLOGY LETTERS

The ways and means that fine tune Sirt1 activity

(2013) Javier R. Revollo et al.   TRENDS IN BIOCHEMICAL SCIENCES

SIRT1 overexpression decreases cisplatin-induced acetylation of NF-κB p65 subunit and cytotoxicity in renal proximal tubule cells

(2012) Yu Jin Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis

(2012) X. Huang et al.   CANCER RESEARCH

Sirtuins and Pyridine Nucleotides

(2012) Maha Abdellatif   CIRCULATION RESEARCH

Regulation of Cell Survival and Death by Pyridine Nucleotides

(2012) Shin-ichi Oka et al.   CIRCULATION RESEARCH

The Antioxidant 3H-1,2-Dithiole-3-Thione Potentiates Advanced Glycation End-Product-Induced Oxidative Stress in SH-SY5Y Cells

(2012) Robert Pazdro et al.   Experimental Diabetes Research

Beta-Lapachone, a Modulator of NAD Metabolism, Prevents Health Declines in Aged Mice

(2012) Jeong-sook Lee et al.   PLoS One

Activation of NAD(P)H:quinone oxidoreductase ameliorates spontaneous hypertension in an animal model via modulation of eNOS activity

(2011) Yong-Hoon Kim et al.   CARDIOVASCULAR RESEARCH

Modulating Endogenous NQO1 Levels Identifies Key Regulatory Mechanisms of Action of  -Lapachone for Pancreatic Cancer Therapy

(2011) L. S. Li et al.   CLINICAL CANCER RESEARCH

Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury

(2011) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prevention of salt-induced renal injury by activation of NAD(P)H:quinone oxidoreductase 1, associated with NADPH oxidase

(2011) Yong-Hoon Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

NQO1-Dependent Redox Cycling of Idebenone: Effects on Cellular Redox Potential and Energy Levels

(2011) Roman H. Haefeli et al.   PLoS One

The impact of acetylation and deacetylation on the p53 pathway

(2011) Christopher L. Brooks et al.   Protein & Cell

Kidney-specific Overexpression of Sirt1 Protects against Acute Kidney Injury by Retaining Peroxisome Function

(2010) Kazuhiro Hasegawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of NADPH Oxidases in Cisplatin-Induced Reactive Oxygen Species Generation and Ototoxicity

(2010) H.-J. Kim et al.   JOURNAL OF NEUROSCIENCE

The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets

(2010) Raga Krishnakumar et al.   MOLECULAR CELL

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

The miR-34 family in cancer and apoptosis

(2009) H Hermeking   CELL DEATH AND DIFFERENTIATION

Activation of NAD(P)H:Quinone Oxidoreductase 1 Prevents Arterial Restenosis by Suppressing Vascular Smooth Muscle Cell Proliferation

(2009) Sun-Yee Kim et al.   CIRCULATION RESEARCH

Pharmacological Stimulation of NADH Oxidation Ameliorates Obesity and Related Phenotypes in Mice

(2009) J. H. Hwang et al.   DIABETES

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes

(2009) Shin-ichiro Imai   Frontiers in Bioscience-Landmark

Parthanatos, a messenger of death

(2009) Karen Kate David   Frontiers in Bioscience-Landmark

siRNA Targeted to p53 Attenuates Ischemic and Cisplatin-Induced Acute Kidney Injury

(2009) B. A. Molitoris et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

(2008) Marcella Fulco et al.   DEVELOPMENTAL CELL

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA