Aspalathin Reverts Doxorubicin-Induced Cardiotoxicity through Increased Autophagy and Decreased Expression of p53/mTOR/p62 Signaling

Enhanced-autophagy by exenatide mitigates doxorubicin-induced cardiotoxicity

(2017) Kyung Hye Lee et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Polyphenols, autophagy and doxorubicin-induced cardiotoxicity

(2017) S. Shabalala et al.   LIFE SCIENCES

The Transcription Profile Unveils the Cardioprotective Effect of Aspalathin against Lipid Toxicity in an In Vitro H9c2 Model

(2017) Rabia Johnson et al.   MOLECULES

Aspalathin Protects the Heart against Hyperglycemia-Induced Oxidative Damage by Up-Regulating Nrf2 Expression

(2017) Phiwayinkosi Dludla et al.   MOLECULES

Cardiac Complications of Cancer Therapy: Pathophysiology, Identification, Prevention, Treatment, and Future Directions

(2017) Diwakar Jain et al.   Current Cardiology Reports

Resveratrol-induced autophagy promotes survival and attenuates doxorubicin-induced cardiotoxicity

(2016) Jun Gu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Aspalathin, a dihydrochalconeC-glucoside, protects H9c2 cardiomyocytes against high glucose induced shifts in substrate preference and apoptosis

(2016) Rabia Johnson et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Astragalus polysaccharide restores autophagic flux and improves cardiomyocyte function in doxorubicin-induced cardiotoxicity

(2016) Yuan Cao et al.   Oncotarget

Resveratrol protects cardiomyocytes from doxorubicin-induced apoptosis through the AMPK/P53 pathway

(2015) MI-HUA LIU et al.   Molecular Medicine Reports

p53-induced autophagy and senescence

(2015) Xinbing Sui et al.   Oncotarget

Dexrazoxane may prevent doxorubicin-induced DNA damage via depleting both Topoisomerase II isoforms

(2014) Shiwei Deng et al.   BMC CANCER

Cancer treatment and survivorship statistics, 2014

(2014) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Catching broken hearts: pre-clinical detection of doxorubicin and trastuzumab mediated cardiac dysfunction in the breast cancer setting

(2014) Mahwash F. Saeed et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy

(2013) Amber N. Hale et al.   Autophagy

Crosstalk between apoptosis, necrosis and autophagy

(2013) Vassiliki Nikoletopoulou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development

(2013) Mayur V. Jain et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mito-Tempol and Dexrazoxane Exhibit Cardioprotective and Chemotherapeutic Effects through Specific Protein Oxidation and Autophagy in a Syngeneic Breast Tumor Preclinical Model

(2013) Jennifer S. Dickey et al.   PLoS One

Autophagy upregulation promotes survival and attenuates doxorubicin-induced cardiotoxicity

(2012) Balindiwe J.N. Sishi et al.   BIOCHEMICAL PHARMACOLOGY

AMP-activated protein kinase, stress responses and cardiovascular diseases

(2012) Shaobin Wang et al.   CLINICAL SCIENCE

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Caloric Restriction Mimetic 2-Deoxyglucose Antagonizes Doxorubicin-induced Cardiomyocyte Death by Multiple Mechanisms

(2011) Kai Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore

(2010) Melissa N. Quinsay et al.   Autophagy

The Association of AMPK with ULK1 Regulates Autophagy

(2010) Jong Woo Lee et al.   PLoS One

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Cardiomyocyte death in doxorubicin-induced cardiotoxicity

(2009) Yi-Wei Zhang et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Antioxidant Activity of the Dihydrochalcones Aspalathin and Nothofagin and Their Corresponding Flavones in Relation to Other Rooibos (Aspalathus linearis) Flavonoids, Epigallocatechin Gallate, and Trolox

(2009) Petra W. Snijman et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transcription Factor GATA4 Inhibits Doxorubicin-induced Autophagy and Cardiomyocyte Death

(2009) Satoru Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure

(2008) Lihe Lu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY