Genetic depletion of Polo-like kinase 1 leads to embryonic lethality due to mitotic aberrancies

Multiple Requirements of PLK1 during Mouse Oocyte Maturation

(2015) Petr Solc et al.   PLoS One

Polo-like kinase 1 is essential for the first mitotic division in the mouse embryo

(2013) V. Baran et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Identification of Potential Plk1 Targets in a Cell-Cycle Specific Proteome through Structural Dynamics of Kinase and Polo Box-Mediated Interactions

(2013) Nousheen Bibi et al.   PLoS One

High Mitotic Activity of Polo-like Kinase 1 Is Required for Chromosome Segregation and Genomic Integrity in Human Epithelial Cells

(2012) Robert F. Lera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore–microtubule attachments

(2012) Ana R.R. Maia et al.   JOURNAL OF CELL BIOLOGY

Sequential phosphorylation of GRASP65 during mitotic Golgi disassembly

(2012) D. Tang et al.   Biology Open

From Plk1 to Plk5

(2011) Guillermo de Cárcer et al.   CELL CYCLE

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells

(2011) Monika Raab et al.   Nature Communications

A role for Drosophila Polo protein in chromosome resolution and segregation during mitosis

(2010) Susana Godinho et al.   CELL CYCLE

Polo-box domain: a versatile mediator of polo-like kinase function

(2010) Jung-Eun Park et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

(2010) Klaus Strebhardt   NATURE REVIEWS DRUG DISCOVERY

Polo-like kinase inhibitors: an emerging opportunity for cancer therapeutics

(2009) Puneet Chopra et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The decision to enter mitosis: feedback and redundancy in the mitotic entry network

(2009) Arne Lindqvist et al.   JOURNAL OF CELL BIOLOGY

Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells

(2009) Mark E. Burkard et al.   PLOS BIOLOGY

Polo-Like Kinase 1 Directs Assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF Complex to Initiate Cleavage Furrow Formation

(2009) Benjamin A. Wolfe et al.   PLOS BIOLOGY

Sequestration of Polo kinase to microtubules by phosphopriming-independent binding to Map205 is relieved by phosphorylation at a CDK site in mitosis

(2008) V. Archambault et al.   GENES & DEVELOPMENT

Polo-Like Kinase 1 Is Essential for Early Embryonic Development and Tumor Suppression

(2008) L.-Y. Lu et al.   MOLECULAR AND CELLULAR BIOLOGY

Genomic stability and tumour suppression by the APC/C cofactor Cdh1

(2008) Irene García-Higuera et al.   NATURE CELL BIOLOGY