High Mitotic Activity of Polo-like Kinase 1 Is Required for Chromosome Segregation and Genomic Integrity in Human Epithelial Cells

Enabling and Disabling Polo-like Kinase 1 Inhibition through Chemical Genetics

(2012) Mark E. Burkard et al.   ACS Chemical Biology

Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides Using Oxime-Based Diversification

(2012) Fa Liu et al.   ACS Chemical Biology

POLO ensures chromosome bi-orientation by preventing and correcting erroneous chromosome-spindle attachments

(2012) T. Moutinho-Santos et al.   JOURNAL OF CELL SCIENCE

DNA breaks and chromosome pulverization from errors in mitosis

(2012) Karen Crasta et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres

(2012) Mar Carmena et al.   PLOS BIOLOGY

Polo-like Kinase 1 Inhibitors and Their Potential Role in Anticancer Therapy, with a Focus on NSCLC

(2011) R. H. Medema et al.   CLINICAL CANCER RESEARCH

A phase I, dose-escalation study of the novel Polo-like kinase inhibitor volasertib (BI 6727) in patients with advanced solid tumours

(2011) Patrick Schöffski et al.   EUROPEAN JOURNAL OF CANCER

Welcome to a new kind of tension: translating kinetochore mechanics into a wait-anaphase signal

(2010) Thomas J. Maresca et al.   JOURNAL OF CELL SCIENCE

Distinct Concentration-Dependent Effects of the Polo-like Kinase 1-Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis

(2009) A. G. Gilmartin et al.   CANCER RESEARCH

How do anti-mitotic drugs kill cancer cells?

(2009) K. E. Gascoigne et al.   JOURNAL OF CELL SCIENCE

Functional Dynamics of Polo-Like Kinase 1 at the Centrosome

(2009) K. Kishi et al.   MOLECULAR AND CELLULAR BIOLOGY

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

(2009) Sang-Moon Yun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells

(2009) Mark E. Burkard et al.   PLOS BIOLOGY

Polo-Like Kinase 1 Directs Assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF Complex to Initiate Cleavage Furrow Formation

(2009) Benjamin A. Wolfe et al.   PLOS BIOLOGY

Plk1-dependent Phosphorylation Regulates Functions of DNA Topoisomerase IIα in Cell Cycle Progression

(2008) Hongchang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY