Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex †

Repurposing of Idebenone as a potential anticancer agent

(2019) Elisabetta Damiani et al.   BIOCHEMICAL JOURNAL

Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson’s Disease Mice

(2019) Aijuan Yan et al.   Frontiers in Cellular Neuroscience

Raxone dans la neuropathie optique de Leber : retour d’expérience parisienne

(2019) C. Orssaud et al.   JOURNAL FRANCAIS D OPHTALMOLOGIE

Patient reported outcomes in Friedreich's Ataxia after withdrawal from Idebenone

(2019) Arron Cook et al.   ACTA NEUROLOGICA SCANDINAVICA

Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

(2018) Vassilis Bourganis et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Cyclodextrins: structure, physicochemical properties and pharmaceutical applications

(2018) Phatsawee Jansook et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Idebenone: Novel Strategies to Improve Its Systemic and Local Efficacy

(2018) Lucia Montenegro et al.   Nanomaterials

Metyrapone-β-cyclodextrin supramolecular interactions inferred by complementary spectroscopic/spectrometric and computational studies

(2018) Giuseppe Floresta et al.   JOURNAL OF MOLECULAR STRUCTURE

Experimental and molecular docking investigations on the inclusion mechanism of the complex of phloridzin and hydroxypropyl-β-cyclodextrin

(2017) Chun-Ling Zhang et al.   FOOD CHEMISTRY

Physicochemical properties of inclusion complexes of highly soluble β-cyclodextrins with highly hydrophobic testosterone propionate

(2017) Christian Celia et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

“Host-guest” interactions in Captisol ® /Coumestrol inclusion complex: UV–vis, FTIR-ATR and Raman studies

(2017) Valentina Venuti et al.   JOURNAL OF MOLECULAR STRUCTURE

International Consensus Statement on the Clinical and Therapeutic Management of Leber Hereditary Optic Neuropathy

(2017) Valerio Carelli et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Structural dynamics and binding free energy of neral-cyclodextrins inclusion complexes: molecular dynamics simulation

(2017) Peerapong Wongpituk et al.   MOLECULAR SIMULATION

Studies on the Inclusion Complexes of Daidzein with β-Cyclodextrin and Derivatives

(2017) Shujing Li et al.   MOLECULES

Rutin-loaded chitosan microspheres: Characterization and evaluation of the anti-inflammatory activity

(2016) Donato Cosco et al.   CARBOHYDRATE POLYMERS

The death of the Job plot, transparency, open science and online tools, uncertainty estimation methods and other developments in supramolecular chemistry data analysis

(2016) D. Brynn Hibbert et al.   CHEMICAL COMMUNICATIONS

Idebenone: A Review in Leber’s Hereditary Optic Neuropathy

(2016) Katherine A. Lyseng-Williamson   DRUGS

Recognizing the Limited Applicability of Job Plots in Studying Host–Guest Interactions in Supramolecular Chemistry

(2016) Filip Ulatowski et al.   JOURNAL OF ORGANIC CHEMISTRY

Solute–Solvent Interactions in Aqueous Solutions of Sulfobutyl Ether-β-cyclodextrin As Probed by UV-Raman and FTIR-ATR Analysis

(2016) Valentina Venuti et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Theoretical and Experimental Study of Inclusion Complexes of β-Cyclodextrins with Chalcone and 2′,4′-Dihydroxychalcone

(2016) Matias I. Sancho et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Characterization and Enhanced Antioxidant Activity of the Cysteinyl β-Cyclodextrin-Baicalein Inclusion Complex

(2016) Hwanhee Kim et al.   MOLECULES

Cyclodextrins as Emerging Therapeutic Tools in the Treatment of Cholesterol-Associated Vascular and Neurodegenerative Diseases

(2016) Caroline Coisne et al.   MOLECULES

The Potential of Cyclodextrins as Novel Active Pharmaceutical Ingredients: A Short Overview

(2016) Massimiliano di Cagno   MOLECULES

Idebenone reduces respiratory complications in patients with Duchenne muscular dystrophy

(2016) Craig M. McDonald et al.   NEUROMUSCULAR DISORDERS

Pharmacological effect of a new idebenone formulation in a model of carrageenan-induced inflammatory pain

(2016) Filomena Lauro et al.   PHARMACOLOGICAL RESEARCH

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

(2016) Sebastian Zimmer et al.   Science Translational Medicine

The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities

(2015) Samuel Genheden et al.   Expert Opinion on Drug Discovery

Cyclodextrins enhance the antioxidant activity of essential oils from three Lamiaceae species

(2015) Patrícia Costa et al.   INDUSTRIAL CROPS AND PRODUCTS

Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial

(2015) Gunnar M Buyse et al.   LANCET

YASARA View—molecular graphics for all devices—from smartphones to workstations

(2014) Elmar Krieger et al.   BIOINFORMATICS

Idebenone and neuroprotection: antioxidant, pro-oxidant, or electron carrier?

(2014) Sausan Jaber et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Direct evidence of gel–sol transition in cyclodextrin-based hydrogels as revealed by FTIR-ATR spectroscopy

(2014) Vincenza Crupi et al.   Soft Matter

Modelling the interplay between covalent and physical interactions in cyclodextrin-based hydrogel: effect of water confinement

(2013) Vincenza Crupi et al.   Soft Matter

Cyclodextrins and Antioxidants

(2012) José Manuel López-Nicolás et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Phase solubility and FTIR-ATR studies of idebenone/sulfobutyl ether β-cyclodextrin inclusion complex

(2012) C. Cannavà et al.   JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY

Effect of Cross-Linking Properties on the Vibrational Dynamics of Cyclodextrins-Based Polymers: An Experimental–Numerical Study

(2012) Franca Castiglione et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Gemcitabine-loaded biocompatible nanocapsules for the effective treatment of human cancer

(2012) Donatella Paolino et al.   Nanomedicine

Water soluble complexes of curcumin with cyclodextrins: Characterization by FT-Raman spectroscopy

(2012) P.R. Krishna Mohan et al.   VIBRATIONAL SPECTROSCOPY

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes

(2011) Thorsteinn Loftsson et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Idebenone Induces Apoptotic Cell Death in the Human Dopaminergic Neuroblastoma SHSY-5Y Cells

(2011) Kwok-Keung Tai et al.   NEUROTOXICITY RESEARCH

A Phase 3, Double-blind, Placebo-Controlled Trial of Idebenone in Friedreich Ataxia

(2010) David R. Lynch et al.   ARCHIVES OF NEUROLOGY

Comparison of different absorption enhancers on the intranasal absorption of isosorbide dinitrate in rats

(2010) Lidong Na et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Intermediate-Dose Idebenone and Quality of Life in Friedreich Ataxia

(2010) John F. Brandsema et al.   PEDIATRIC NEUROLOGY

Pharmacokinetics and metabolism of idebenone in healthy male subjects

(2009) Michael Bodmer et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacokinetic evaluation and modeling of formulated levodopa intranasal delivery systems

(2009) Tae Kyung Kim et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Nanoparticles for direct nose-to-brain delivery of drugs

(2009) Alpesh Mistry et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with β-cyclodextrin

(2008) Rosanna Stancanelli et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Spectrofluorimetric Study on Inclusion Complexation of 2-Amino-6-fluorobenzothiazole with β-Cyclodextrin

(2008) Rajaram Rajamohan et al.   COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS