Attenuation of Zika Virus by Passage in Human HeLa Cells

A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle

(2019) Anna Płaszczyca et al.   PLoS Pathogens

Refinement and Analysis of the Mature Zika Virus Cryo-EM Structure at 3.1 Å Resolution

(2018) Madhumati Sevvana et al.   STRUCTURE

The structural proteins of epidemic and historical strains of Zika virus differ in their ability to initiate viral infection in human host cells

(2018) Sandra Bos et al.   VIROLOGY

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

(2018) Hongjie Xia et al.   Nature Communications

Current status of Zika vaccine development: Zika vaccines advance into clinical evaluation

(2018) Alan D. T. Barrett   npj Vaccines

Whole genome sequencing, variant analysis, phylogenetics, and deep sequencing of Zika virus strains

(2018) Susmita Shrivastava et al.   Scientific Reports

Role of Zika Virus prM Protein in Viral Pathogenicity and Use in Vaccine Development

(2018) Peter Nambala et al.   Frontiers in Microbiology

Recent Advances in Zika Virus Vaccines

(2018) Himanshu Garg et al.   Viruses-Basel

Structural and Nonstructural Genes Contribute to the Genetic Diversity of RNA Viruses

(2018) Natalie D. Collins et al.   mBio

Virulence determinants of West Nile virus: how can these be used for vaccine design?

(2017) Jaclyn A Kaiser et al.   Future Virology

Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes

(2017) Yang Liu et al.   NATURE

A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

(2017) Chao Shan et al.   NATURE MEDICINE

A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

(2017) Ling Yuan et al.   SCIENCE

Pathogenesis and sexual transmission of Spondweni and Zika viruses

(2017) Erin M. McDonald et al.   PLoS Neglected Tropical Diseases

A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro

(2017) Deping Wang et al.   Scientific Reports

Zika virus NS1, a pathogenicity factor with many faces

(2016) Rolf Hilgenfeld   EMBO JOURNAL

Extended surface for membrane association in Zika virus NS1 structure

(2016) W Clay Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The South Pacific epidemic strain of Zika virus replicates efficiently in human epithelial A549 cells leading to IFN-β production and apoptosis induction

(2016) Etienne Frumence et al.   VIROLOGY

Extended surface for membrane association in Zika virus NS1 structure

(2016) W Clay Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype

(2016) Kimberly A. Dowd et al.   Cell Reports

Characterization of Lethal Zika Virus Infection in AG129 Mice

(2016) Matthew T. Aliota et al.   PLoS Neglected Tropical Diseases

A Single Amino Acid Substitution in the M Protein Attenuates Japanese Encephalitis Virus in Mammalian Hosts

(2015) Mélissanne de Wispelaere et al.   JOURNAL OF VIROLOGY

Genetic Determinants of Japanese Encephalitis Virus Vaccine Strain SA14-14-2 That Govern Attenuation of Virulence in Mice

(2015) Gregory D. Gromowski et al.   JOURNAL OF VIROLOGY

Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins

(2015) Pietro Scaturro et al.   PLoS Pathogens

Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

(2014) D. L. Akey et al.   SCIENCE

The Flavivirus Precursor Membrane-Envelope Protein Complex: Structure and Maturation

(2008) L. Li et al.   SCIENCE