Recent Advances in Zika Virus Vaccines

Evaluating Vaccination Strategies for Zika Virus in the Americas

(2018) David P. Durham et al.   ANNALS OF INTERNAL MEDICINE

Insect cell-produced recombinant protein subunit vaccines protect against Zika virus infection

(2018) Panke Qu et al.   ANTIVIRAL RESEARCH

Recombinant Chimpanzee Adenovirus Vaccine AdC7-M/E Protects against Zika Virus Infection and Testis Damage

(2018) Kun Xu et al.   JOURNAL OF VIROLOGY

Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials

(2018) Kayvon Modjarrad et al.   LANCET

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

(2018) Martin R Gaudinski et al.   LANCET

Rapid response to an emerging infectious disease – Lessons learned from development of a synthetic DNA vaccine targeting Zika virus

(2018) Sagar B. Kudchodkar et al.   MICROBES AND INFECTION

Immunization with phage virus-like particles displaying Zika virus potential B-cell epitopes neutralizes Zika virus infection of monkey kidney cells

(2018) Rupsa Basu et al.   VACCINE

A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses

(2018) Natalie A. Prow et al.   Nature Communications

Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone

(2018) Xiao-Feng Li et al.   Nature Communications

Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors

(2018) César López-Camacho et al.   Nature Communications

A VSV-based Zika virus vaccine protects mice from lethal challenge

(2018) Jackson Emanuel et al.   Scientific Reports

The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials

(2018) Ellen Suder et al.   Human Vaccines & Immunotherapeutics

Zika virus like particles elicit protective antibodies in mice

(2018) Mauricio A. Salvo et al.   PLoS Neglected Tropical Diseases

Critical neutralizing fragment of Zika virus EDIII elicits cross-neutralization and protection against divergent Zika viruses

(2018) Wanbo Tai et al.   Emerging Microbes & Infections

Recombinant Zika Virus Subunits Are Immunogenic and Efficacious in Mice

(2018) Albert To et al.   mSphere

Passive Transfer of Immune Sera Induced by a Zika Virus-Like Particle Vaccine Protects AG129 Mice Against Lethal Zika Virus Challenge

(2018) Diego Espinosa et al.   EBioMedicine

Incorporation of NS1 and prM/M are important to confer effective protection of adenovirus-vectored Zika virus vaccine carrying E protein

(2018) Xinglong Liu et al.   npj Vaccines

Zika Virus Baculovirus-Expressed Virus-Like Particles Induce Neutralizing Antibodies in Mice

(2018) Shiyu Dai et al.   VIROLOGICA SINICA

Adenoviral vector type 26 encoding Zika virus (ZIKV) M-Env antigen induces humoral and cellular immune responses and protects mice and nonhuman primates against ZIKV challenge

(2018) Freek Cox et al.   PLoS One

A single-dose plasmid-launched live-attenuated Zika vaccine induces protective immunity

(2018) Jing Zou et al.   EBioMedicine

E90 subunit vaccine protects mice from Zika virus infection and microcephaly

(2018) Xingliang Zhu et al.   Acta Neuropathologica Communications

An update on Zika vaccine developments

(2017) Anna Durbin et al.   Expert Review of Vaccines

Cutting Edge: Innate Immune Augmenting Vesicular Stomatitis Virus Expressing Zika Virus Proteins Confers Protective Immunity

(2017) Dillon Betancourt et al.   JOURNAL OF IMMUNOLOGY

Development of Virus-Like-Particle Vaccine and Reporter Assay for Zika Virus

(2017) Himanshu Garg et al.   JOURNAL OF VIROLOGY

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

(2017) Norbert Pardi et al.   NATURE

A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

(2017) Chao Shan et al.   NATURE MEDICINE

Safety and Immunogenicity of an Anti–Zika Virus DNA Vaccine — Preliminary Report

(2017) Pablo Tebas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Plant-produced Zika virus envelope protein elicits neutralizing immune responses that correlate with protective immunity against Zika virus in mice

(2017) Ming Yang et al.   PLANT BIOTECHNOLOGY JOURNAL

Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity

(2017) Susana V. Bardina et al.   SCIENCE

Durability and correlates of vaccine protection against Zika virus in rhesus monkeys

(2017) Peter Abbink et al.   Science Translational Medicine

Immunization of Zika virus envelope protein domain III induces specific and neutralizing immune responses against Zika virus

(2017) Ming Yang et al.   VACCINE

The flavivirus capsid protein: Structure, function and perspectives towards drug design

(2017) Edson R.A. Oliveira et al.   VIRUS RESEARCH

Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins

(2017) Shun Chen et al.   Viruses-Basel

Understanding Zika Virus Stability and Developing a Chimeric Vaccine through Functional Analysis

(2017) Xuping Xie et al.   mBio

High Zika Virus Seroprevalence in Salvador, Northeastern Brazil Limits the Potential for Further Outbreaks

(2017) Eduardo Martins Netto et al.   mBio

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

(2017) Chao Shan et al.   Nature Communications

Functional Analysis of Glycosylation of Zika Virus Envelope Protein

(2017) Camila R. Fontes-Garfias et al.   Cell Reports

Zika Virus Infection as a Cause of Congenital Brain Abnormalities and Guillain–Barré Syndrome: Systematic Review

(2017) Fabienne Krauer et al.   PLOS MEDICINE

Zika virus-like particle (VLP) based vaccine

(2017) Hélène Boigard et al.   PLoS Neglected Tropical Diseases

Live Attenuated Yellow Fever 17D Vaccine: A Legacy Vaccine Still Controlling Outbreaks In Modern Day

(2017) Natalie D. Collins et al.   Current Infectious Disease Reports

Vital Signs: Update on Zika Virus–Associated Birth Defects and Evaluation of All U.S. Infants with Congenital Zika Virus Exposure — U.S. Zika Pregnancy Registry, 2016

(2017) Megan R. Reynolds et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine

(2017) Yujiao Yang et al.   EBioMedicine

An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model

(2017) Jasdave S. Chahal et al.   Scientific Reports

Protective efficacy of Zika vaccine in AG129 mouse model

(2017) K. Sumathy et al.   Scientific Reports

Virus-like particles that display Zika virus envelope protein domain III induce potent neutralizing immune responses in mice

(2017) Ming Yang et al.   Scientific Reports

Zika virus: History, emergence, biology, and prospects for control

(2016) Scott C. Weaver et al.   ANTIVIRAL RESEARCH

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

(2016) Hengli Tang et al.   Cell Stem Cell

Zika virus genome from the Americas

(2016) Antoine Enfissi et al.   LANCET

Vaccine protection against Zika virus from Brazil

(2016) Rafael A. Larocca et al.   NATURE

Rapid development of a DNA vaccine for Zika virus

(2016) K. A. Dowd et al.   SCIENCE

Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys

(2016) P. Abbink et al.   SCIENCE

In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine

(2016) Karuppiah Muthumani et al.   npj Vaccines

Virus-Like Particles Containing the Tetrameric Ectodomain of Influenza Matrix Protein 2 and Flagellin Induce Heterosubtypic Protection in Mice

(2013) Li Wang et al.   Biomed Research International

Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L

(2011) B. R. Anderson et al.   NUCLEIC ACIDS RESEARCH

Development of a recombinant tetravalent dengue virus vaccine: Immunogenicity and efficacy studies in mice and monkeys

(2010) David E. Clements et al.   VACCINE

Zika Virus Outbreak on Yap Island, Federated States of Micronesia

(2009) Mark R. Duffy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protective efficacy of a recombinant subunit West Nile virus vaccine in domestic geese (Anser anser)

(2008) Susan I. Jarvi et al.   VACCINE