Current status of Zika vaccine development: Zika vaccines advance into clinical evaluation

Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials

(2018) Kayvon Modjarrad et al.   LANCET

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

(2018) Martin R Gaudinski et al.   LANCET

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

(2017) Norbert Pardi et al.   NATURE

A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

(2017) Chao Shan et al.   NATURE MEDICINE

Safety and Immunogenicity of an Anti–Zika Virus DNA Vaccine — Preliminary Report

(2017) Pablo Tebas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques

(2017) Diogo M. Magnani et al.   Science Translational Medicine

Durability and correlates of vaccine protection against Zika virus in rhesus monkeys

(2017) Peter Abbink et al.   Science Translational Medicine

DNA vaccination protects mice against Zika virus-induced damage to the testes

(2017) Bryan D. Griffin et al.   Nature Communications

Vaccine protection against Zika virus from Brazil

(2016) Rafael A. Larocca et al.   NATURE

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

(2016) Gopal Sapparapu et al.   NATURE

Considerations for Developing a Zika Virus Vaccine

(2016) Hilary D. Marston et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fast-Track Zika Vaccine Development — Is It Possible?

(2016) Stephen J. Thomas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rapid development of a DNA vaccine for Zika virus

(2016) K. A. Dowd et al.   SCIENCE

Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys

(2016) P. Abbink et al.   SCIENCE

In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine

(2016) Karuppiah Muthumani et al.   npj Vaccines