Arming Filamentous Bacteriophage, a Nature-Made Nanoparticle, for New Vaccine and Immunotherapeutic Strategies

Design of a mimotope-peptide based double epitope vaccine against disseminated candidiasis

(2019) Hong Xin et al.   VACCINE

Immunostimulatory Phosphatidylmonogalactosyldiacylglycerols (PGDG) from the Marine Diatom Thalassiosira weissflogii: Inspiration for a Novel Synthetic Toll-Like Receptor 4 Agonist

(2019) Emiliano Manzo et al.   Marine Drugs

Phage therapy’s latest makeover

(2019) Charles Schmidt   NATURE BIOTECHNOLOGY

Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

(2019) Rebekah M. Dedrick et al.   NATURE MEDICINE

Differential human antibody repertoires following Zika infection and the implications for serodiagnostics and disease outcome

(2019) Supriya Ravichandran et al.   Nature Communications

Manufacturing and ambient stability of shelf freeze dried bacteriophage powder formulations

(2018) Yajie Zhang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nontoxic engineered virus nanofibers as an efficient agent for the prevention and detection of fungal infection

(2018) Yicun Wang et al.   Nano Research

Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function

(2018) Srinivasan Rengachari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial Delivery Vehicles for Allergens and Allergen-Derived Peptides in Immunotherapy of Allergic Diseases

(2018) Abida Zahirović et al.   Frontiers in Microbiology

Beyond Bacteria: Bacteriophage-Eukaryotic Host Interactions Reveal Emerging Paradigms of Health and Disease

(2018) Anushila Chatterjee et al.   Frontiers in Microbiology

Thermoresponsive Bacteriophage Nanocarrier as a Gene Delivery Vector Targeted to the Gastrointestinal Tract

(2018) Katawut Namdee et al.   Molecular Therapy-Nucleic Acids

Vaccination With Recombinant Filamentous fd Phages Against Parasite Infection Requires TLR9 Expression

(2018) João F. Gomes-Neto et al.   Frontiers in Immunology

Vectorized Delivery of Alpha-GalactosylCeramide and Tumor Antigen on Filamentous Bacteriophage fd Induces Protective Immunity by Enhancing Tumor-Specific T Cell Response

(2018) Rossella Sartorius et al.   Frontiers in Immunology

Phage vaccines displaying YGKDVKDLFDYAQE epitope induce protection against systemic candidiasis in mouse model

(2018) Hongxi Shi et al.   VACCINE

Phage-Based Anti-HER2 Vaccination Can Circumvent Immune Tolerance against Breast Cancer

(2018) Caterina Bartolacci et al.   Cancer Immunology Research

ISGylation – a key to lock the cell gates for preventing the spread of threats

(2017) Carolina Villarroya-Beltri et al.   JOURNAL OF CELL SCIENCE

Filamentous Bacteriophage as a Novel Therapeutic Tool for Alzheimer's Disease Treatment

(2017) Beka Solomon   JOURNAL OF ALZHEIMERS DISEASE

Microencapsulation of Clostridium difficile specific bacteriophages using microfluidic glass capillary devices for colon delivery using pH triggered release

(2017) Gurinder K. Vinner et al.   PLoS One

Recombinant Phage Elicits Protective Immune Response against Systemic S. globosa Infection in Mouse Model

(2017) Feng Chen et al.   Scientific Reports

Phage display peptide libraries in molecular allergology: from epitope mapping to mimotope-based immunotherapy

(2016) J. Luzar et al.   ALLERGY

Application of peptide displaying phage as a novel diagnostic probe for human lung adenocarcinoma

(2016) Kyoung Jin Lee et al.   AMINO ACIDS

Glycolipid activators of invariant NKT cells as vaccine adjuvants

(2016) Shalu Sharma Kharkwal et al.   IMMUNOGENETICS

Genetically manipulated phages with improved pH resistance for oral administration in veterinary medicine

(2016) Franklin L. Nobrega et al.   Scientific Reports

An Introduction to B-Cell Epitope Mapping and In Silico Epitope Prediction

(2016) Lenka Potocnakova et al.   Journal of Immunology Research

Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response

(2015) R. Sartorius et al.   EMBO Molecular Medicine

Gut Inflammation and Immunity: What Is the Role of the Human Gut Virome?

(2015) Alfredo Focà et al.   MEDIATORS OF INFLAMMATION

Mapping and characterization of antigenic epitopes of arginine kinase of Scylla paramamosain

(2015) Yang Yang et al.   MOLECULAR IMMUNOLOGY

Targeting glioblastoma via intranasal administration of Ff bacteriophages

(2015) Eyal Dor-On et al.   Frontiers in Microbiology

Ff-nano, short functionalized nanorods derived from Ff (f1, fd, or M13) filamentous bacteriophage

(2015) Sadia Sattar et al.   Frontiers in Microbiology

Beyond phage display: non-traditional applications of the filamentous bacteriophage as a vaccine carrier, therapeutic biologic, and bioconjugation scaffold

(2015) Kevin A. Henry et al.   Frontiers in Microbiology

Stimulation of Innate and Adaptive Immunity by Using Filamentous Bacteriophage fd Targeted to DEC-205

(2015) Luciana D’Apice et al.   Journal of Immunology Research

Mucosal vaccination with phage-displayed tumour antigens identified through proteomics-based strategy inhibits the growth and metastasis of 4T1 breast adenocarcinoma

(2014) Mohsen Shadidi et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The Use of Filamentous Bacteriophage fd to Deliver MAGE-A10 or MAGE-A3 HLA-A2-Restricted Peptides and to Induce Strong Antitumor CTL Responses

(2014) R. Sartorius et al.   JOURNAL OF IMMUNOLOGY

Phage idiotype vaccination: first phase I/II clinical trial in patients with multiple myeloma

(2014) Tim Roehnisch et al.   Journal of Translational Medicine

Phage therapy gets revitalized

(2014) Sara Reardon   NATURE

Alum and Squalene-Oil-in-Water Emulsion Enhance the Titer and Avidity of Anti-Aβ Antibodies Induced by Multimeric Protein Antigen (1–11)E2, Preserving the Igg1-Skewed Isotype Distribution

(2014) Francesca Mantile et al.   PLoS One

Structure and assembly of filamentous bacteriophages

(2014) D.A. Marvin et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Architectural Insight into Inovirus-Associated Vectors (IAVs) and Development of IAV-Based Vaccines Inducing Humoral and Cellular Responses: Implications in HIV-1 Vaccines

(2014) Kyriakos Hassapis et al.   Viruses-Basel

Hybrid phage displaying SLAQVKYTSASSI induces protection againstCandida albicanschallenge in BALB/c mice

(2014) Yicun Wang et al.   Human Vaccines & Immunotherapeutics

The Warburg effect then and now: From cancer to inflammatory diseases

(2013) Eva M. Palsson-McDermott et al.   BIOESSAYS

Lipid antigens in immunity

(2013) C. Marie Dowds et al.   BIOLOGICAL CHEMISTRY

Intravenous infusion of phage-displayed antibody library in human cancer patients: enrichment and cancer-specificity of tumor-homing phage-antibodies

(2013) Girja S. Shukla et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5'-terminal regions of cap0-, cap1- and 5'ppp- mRNAs

(2013) P. Kumar et al.   NUCLEIC ACIDS RESEARCH

Cathepsin L1 mimotopes with adjuvant Quil A induces a Th1/Th2 immune response and confers significant protection against Fasciola hepatica infection in goats

(2013) Abel Villa-Mancera et al.   PARASITOLOGY RESEARCH

Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro

(2013) R. R. Tonelli et al.   Frontiers in Immunology

Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells

(2012) B. Chatterjee et al.   BLOOD

How the Interval between Prime and Boost Injection Affects the Immune Response in a Computational Model of the Immune System

(2012) F. Castiglione et al.   Computational and Mathematical Methods in Medicine

Design and Characterization of a Peptide Mimotope of the HIV-1 gp120 Bridging Sheet

(2012) Marco Schiavone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Filamentous Bacteriophage Fd as an Antigen Delivery System in Vaccination

(2012) Antonella Prisco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Convection-enhanced delivery of M13 bacteriophage to the brain

(2012) Alexander Ksendzovsky et al.   JOURNAL OF NEUROSURGERY

Infective and inactivated filamentous phage as carriers for immunogenic peptides

(2012) Tatiana I. Samoylova et al.   JOURNAL OF VIROLOGICAL METHODS

Evaluation of oral administration of bacteriophages to neonatal calves: Phage survival and impact on fecal Escherichia coli

(2012) M.L.S. Bicalho et al.   Livestock Science

Generating thermal stable variants of protein domains through phage display

(2012) Kritika Pershad et al.   METHODS

Targeted Delivery of siRNA into Breast Cancer Cells via Phage Fusion Proteins

(2012) Deepa Bedi et al.   MOLECULAR PHARMACEUTICS

Refactored M13 Bacteriophage as a Platform for Tumor Cell Imaging and Drug Delivery

(2012) Debadyuti Ghosh et al.   ACS Synthetic Biology

Vaccination with filamentous bacteriophages targeting DEC-205 induces DC maturation and potent anti-tumor T-cell responses in the absence of adjuvants

(2011) Rossella Sartorius et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunological basis of M13 phage vaccine: Regulation under MyD88 and TLR9 signaling

(2010) Shuhei Hashiguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

The inflammasomes: mechanisms of activation and function

(2010) Eicke Latz   CURRENT OPINION IN IMMUNOLOGY

A multimeric immunogen for the induction of immune memory to beta-amyloid

(2010) Francesca Mantile et al.   IMMUNOLOGY AND CELL BIOLOGY

Triggering DTH and CTL Activity by fd Filamentous Bacteriophages: Role of CD4+ T Cells in Memory Responses

(2010) Giovanna Del Pozzo et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Antigen-specific therapy of EAE via intranasal delivery of filamentous phage displaying a myelin immunodominant epitope

(2010) Idan S. Rakover et al.   JOURNAL OF NEUROIMMUNOLOGY

By-passing in vitro screening—next generation sequencing technologies applied to antibody display and in silico candidate selection

(2010) U. Ravn et al.   NUCLEIC ACIDS RESEARCH

Vaccines with MF59 Adjuvant Expand the Antibody Repertoire to Target Protective Sites of Pandemic Avian H5N1 Influenza Virus

(2010) S. Khurana et al.   Science Translational Medicine

Tumor-Specific Bacteriophages Induce Tumor Destruction through Activation of Tumor-Associated Macrophages

(2009) F. Eriksson et al.   JOURNAL OF IMMUNOLOGY

Maturation Pathways of Dendritic Cells Determine TAP1 and TAP2 Levels and Cross-presenting Function

(2009) Andrés López-Albaitero et al.   JOURNAL OF IMMUNOTHERAPY

Antigenic Fingerprinting of H5N1 Avian Influenza Using Convalescent Sera and Monoclonal Antibodies Reveals Potential Vaccine and Diagnostic Targets

(2009) Surender Khurana et al.   PLOS MEDICINE

Microencapsulation of Bacteriophage Felix O1 into Chitosan-Alginate Microspheres for Oral Delivery

(2008) Y. Ma et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antigenic properties of HCMV peptides displayed by filamentous bacteriophages vs. synthetic peptides

(2008) Cristina Ulivieri et al.   IMMUNOLOGY LETTERS

Inexpensive anti-cysticercosis vaccine: S3Pvac expressed in heat inactivated M13 filamentous phage proves effective against naturally acquired Taenia solium porcine cysticercosis

(2008) Julio Morales et al.   VACCINE

Immunogenicity and therapeutic efficacy of phage-displayed beta-amyloid epitopes

(2007) Marianna Esposito et al.   MOLECULAR IMMUNOLOGY