Beyond phage display: non-traditional applications of the filamentous bacteriophage as a vaccine carrier, therapeutic biologic, and bioconjugation scaffold

A non-chromatographic method for the removal of endotoxins from bacteriophages

(2015) Steven D. Branston et al.   BIOTECHNOLOGY AND BIOENGINEERING

Assembly of Viral Hydrogels for Three-Dimensional Conducting Nanocomposites

(2014) Po-Yen Chen et al.   ADVANCED MATERIALS

Specific Probe Selection from Landscape Phage Display Library and Its Application in Enzyme-Linked Immunosorbent Assay of Free Prostate-Specific Antigen

(2014) Qiaolin Lang et al.   ANALYTICAL CHEMISTRY

Genetically engineered bacteriophage delivers a tumor necrosis factor alpha antagonist coating on neural electrodes

(2014) Young Jun Kim et al.   Biomedical Materials

The Use of Filamentous Bacteriophage fd to Deliver MAGE-A10 or MAGE-A3 HLA-A2-Restricted Peptides and to Induce Strong Antitumor CTL Responses

(2014) R. Sartorius et al.   JOURNAL OF IMMUNOLOGY

Phage idiotype vaccination: first phase I/II clinical trial in patients with multiple myeloma

(2014) Tim Roehnisch et al.   Journal of Translational Medicine

Paclitaxel-Loaded PEG-PE-Based Micellar Nanopreparations Targeted with Tumor-Specific Landscape Phage Fusion Protein Enhance Apoptosis and Efficiently Reduce Tumors

(2014) T. Wang et al.   MOLECULAR CANCER THERAPEUTICS

Negative selection and stringency modulation in phage-assisted continuous evolution

(2014) Jacob C Carlson et al.   Nature Chemical Biology

Selection of pancreatic cancer cell-binding landscape phages and their use in development of anticancer nanomedicines

(2014) D. Bedi et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Exploiting gut bacteriophages for human health

(2014) Marion Dalmasso et al.   TRENDS IN MICROBIOLOGY

Bio-mimetic Nanostructure Self-assembled from Au@Ag Heterogeneous Nanorods and Phage Fusion Proteins for Targeted Tumor Optical Detection and Photothermal Therapy

(2014) Fei Wang et al.   Scientific Reports

Hybrid phage displaying SLAQVKYTSASSI induces protection againstCandida albicanschallenge in BALB/c mice

(2014) Yicun Wang et al.   Human Vaccines & Immunotherapeutics

Versatile Three-Dimensional Virus-Based Template for Dye-Sensitized Solar Cells with Improved Electron Transport and Light Harvesting

(2013) Po-Yen Chen et al.   ACS Nano

Chemically linked phage idiotype vaccination in the murine B cell lymphoma 1 model

(2013) Tim Roehnisch et al.   Journal of Translational Medicine

Enhanced tumor delivery and antitumor activity in vivo of liposomal doxorubicin modified with MCF-7-specific phage fusion protein

(2013) Tao Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution

(2013) B. C. Dickinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus-based Photo-Responsive Nanowires Formed By Linking Site-Directed Mutagenesis and Chemical Reaction

(2013) Murali Murugesan et al.   Scientific Reports

Viral host-adaptation: insights from evolution experiments with phages

(2013) James PJ Hall et al.   Current Opinion in Virology

Filamentous phages of Ralstonia solanacearum: double-edged swords for pathogenic bacteria

(2013) Takashi Yamada   Frontiers in Microbiology

Metastatic prostate cancer cell-specific phage-like particles as a targeted gene-delivery system

(2013) Olusegun A Fagbohun et al.   JOURNAL OF NANOBIOTECHNOLOGY

Quantitative Synthesis of Genetically Encoded Glycopeptide Libraries Displayed on M13 Phage

(2012) Simon Ng et al.   ACS Chemical Biology

N-Terminal Labeling of Filamentous Phage To Create Cancer Marker Imaging Agents

(2012) Zachary M. Carrico et al.   ACS Nano

M13 Bacteriophage Display Framework That Allows Sortase-Mediated Modification of Surface-Accessible Phage Proteins

(2012) Gaelen T. Hess et al.   BIOCONJUGATE CHEMISTRY

Bacteriophage-induced aggregation of oil sands tailings

(2012) Susan B. Curtis et al.   BIOTECHNOLOGY AND BIOENGINEERING

Phage display allows identification of zona pellucida-binding peptides with species-specific properties: Novel approach for development of contraceptive vaccines for wildlife

(2012) Tatiana I. Samoylova et al.   JOURNAL OF BIOTECHNOLOGY

Rapid and Sensitive Detection of Salmonella Typhimurium on Eggshells by Using Wireless Biosensors

(2012) YATING CHAI et al.   JOURNAL OF FOOD PROTECTION

Metagenomics-based analysis of viral communities in dairy lagoon wastewater

(2012) F.S. Alhamlan et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Convection-enhanced delivery of M13 bacteriophage to the brain

(2012) Alexander Ksendzovsky et al.   JOURNAL OF NEUROSURGERY

Infective and inactivated filamentous phage as carriers for immunogenic peptides

(2012) Tatiana I. Samoylova et al.   JOURNAL OF VIROLOGICAL METHODS

Targeted Delivery of siRNA into Breast Cancer Cells via Phage Fusion Proteins

(2012) Deepa Bedi et al.   MOLECULAR PHARMACEUTICS

M13 Phage-Functionalized Single-Walled Carbon Nanotubes As Nanoprobes for Second Near-Infrared Window Fluorescence Imaging of Targeted Tumors

(2012) Hyunjung Yi et al.   NANO LETTERS

M13-templated magnetic nanoparticles for targeted in vivo imaging of prostate cancer

(2012) Debadyuti Ghosh et al.   Nature Nanotechnology

Assessing the Diversity and Specificity of Two Freshwater Viral Communities through Metagenomics

(2012) Simon Roux et al.   PLoS One

Dynamic Modulation of DNA Replication and Gene Transcription in Deep-Sea Filamentous Phage SW1 in Response to Changes of Host Growth and Temperature

(2012) Huahua Jian et al.   PLoS One

Landscape phages and their fusion proteins targeted to breast cancer cells

(2012) O. A. Fagbohun et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Generation and Characterization of Phage-GnRH Chemical Conjugates for Potential Use in Cat and Dog Immunocontraception

(2012) A Samoylov et al.   REPRODUCTION IN DOMESTIC ANIMALS

Graphene Sheets Stabilized on Genetically Engineered M13 Viral Templates as Conducting Frameworks for Hybrid Energy-Storage Materials

(2012) Dahyun Oh et al.   Small

Experimental evolution

(2012) Tadeusz J. Kawecki et al.   TRENDS IN ECOLOGY & EVOLUTION

Refactored M13 Bacteriophage as a Platform for Tumor Cell Imaging and Drug Delivery

(2012) Debadyuti Ghosh et al.   ACS Synthetic Biology

Basic research in HIV vaccinology is hampered by reductionist thinking

(2012) Marc H. V. Van Regenmortel   Frontiers in Immunology

Detection of Pathogenic Bacteria Using a Homogeneous Immunoassay Based on Shear Alignment of Virus Particles and Linear Dichroism

(2011) Raúl Pacheco-Gómez et al.   ANALYTICAL CHEMISTRY

Sensitive and Selective Bacterial Detection Using Tetracysteine-Tagged Phages in Conjunction with Biarsenical Dye

(2011) Lina Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phage Displayed HBV Core Antigen with Immunogenic Activity

(2011) Aylin Ozdemir Bahadir et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Effects of bacteriophage on the surface properties of chalcopyrite (CuFeS2), and phage-induced flocculation of chalcopyrite, glacial till, and oil sands tailings

(2011) Susan B. Curtis et al.   BIOTECHNOLOGY AND BIOENGINEERING

Vaccination with filamentous bacteriophages targeting DEC-205 induces DC maturation and potent anti-tumor T-cell responses in the absence of adjuvants

(2011) Rossella Sartorius et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A mimotope peptide of Aβ42 fibril-specific antibodies with Aβ42 fibrillation inhibitory activity induces anti-Aβ42 conformer antibody response by a displayed form on an M13 phage in mice

(2011) Koichi Tanaka et al.   JOURNAL OF NEUROIMMUNOLOGY

A system for the continuous directed evolution of biomolecules

(2011) Kevin M. Esvelt et al.   NATURE

Molecular evolution picks up the PACE

(2011) Adam J Meyer et al.   NATURE BIOTECHNOLOGY

Beyond natural antibodies: the power of in vitro display technologies

(2011) Andrew R M Bradbury et al.   NATURE BIOTECHNOLOGY

Inhibition of Bacterial Conjugation by Phage M13 and Its Protein g3p: Quantitative Analysis and Model

(2011) Abraham Lin et al.   PLoS One

In vivo characteristics of targeted drug-carrying filamentous bacteriophage nanomedicines

(2011) Lilach Vaks et al.   JOURNAL OF NANOBIOTECHNOLOGY

Production of Hydrogen Using Nanocrystalline Protein-Templated Catalysts on M13 Phage

(2010) Brian Neltner et al.   ACS Nano

Immunological basis of M13 phage vaccine: Regulation under MyD88 and TLR9 signaling

(2010) Shuhei Hashiguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chemical Modification of M13 Bacteriophage and Its Application in Cancer Cell Imaging

(2010) Kai Li et al.   BIOCONJUGATE CHEMISTRY

Direct detection of Salmonella typhimurium on fresh produce using phage-based magnetoelastic biosensors

(2010) Suiqiong Li et al.   BIOSENSORS & BIOELECTRONICS

Phage display: Concept, innovations, applications and future

(2010) Jyoti Pande et al.   BIOTECHNOLOGY ADVANCES

Mimotopes selected with a neutralizing antibody against urease B from Helicobacter pylori induce enzyme inhibitory antibodies in mice upon vaccination

(2010) Yan Li et al.   BMC BIOTECHNOLOGY

Exposure of conjugative plasmid carrying Escherichia coli biofilms to male-specific bacteriophages

(2010) Thithiwat May et al.   ISME Journal

Characterization of filamentous bacteriophage PE226 infecting Ralstonia solanacearum strains

(2010) S. Murugaiyan et al.   JOURNAL OF APPLIED MICROBIOLOGY

Triggering DTH and CTL Activity by fd Filamentous Bacteriophages: Role of CD4+ T Cells in Memory Responses

(2010) Giovanna Del Pozzo et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Antibody Fab display and selection through fusion to the pIX coat protein of filamentous phage

(2010) Mark Tornetta et al.   JOURNAL OF IMMUNOLOGICAL METHODS

De Novo Selection of High-Affinity Antibodies from Synthetic Fab Libraries Displayed on Phage as pIX Fusion Proteins

(2010) Lei Shi et al.   JOURNAL OF MOLECULAR BIOLOGY

Antigen-specific therapy of EAE via intranasal delivery of filamentous phage displaying a myelin immunodominant epitope

(2010) Idan S. Rakover et al.   JOURNAL OF NEUROIMMUNOLOGY

Virus-Templated Assembly of Porphyrins into Light-Harvesting Nanoantennae

(2010) Yoon Sung Nam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Paclitaxel-Loaded Polymeric Micelles Modified with MCF-7 Cell-Specific Phage Protein: Enhanced Binding to Target Cancer Cells and Increased Cytotoxicity

(2010) Tao Wang et al.   MOLECULAR PHARMACEUTICS

Cytoplasmic Delivery of Liposomes into MCF-7 Breast Cancer Cells Mediated by Cell-Specific Phage Fusion Coat Protein

(2010) Tao Wang et al.   MOLECULAR PHARMACEUTICS

Evolutionary Selection of New Breast Cancer Cell-Targeting Peptides and Phages with the Cell-Targeting Peptides Fully Displayed on the Major Coat and Their Effects on Actin Dynamics during Cell Internalization

(2010) Gopal Abbineni et al.   MOLECULAR PHARMACEUTICS

Enhanced binding and killing of target tumor cells by drug-loaded liposomes modified with tumor-specific phage fusion coat protein

(2010) Tao Wang et al.   Nanomedicine

Landscape phage fusion protein-mediated targeting of nanomedicines enhances their prostate tumor cell association and cytotoxic efficiency

(2010) Prashanth K. Jayanna et al.   Nanomedicine-Nanotechnology Biology and Medicine

Delivery of siRNA into breast cancer cells via phage fusion protein-targeted liposomes

(2010) Deepa Bedi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Satellite phage TLCφ enables toxigenic conversion by CTX phage through dif site alteration

(2010) Faizule Hassan et al.   NATURE

Biologically templated photocatalytic nanostructures for sustained light-driven water oxidation

(2010) Yoon Sung Nam et al.   Nature Nanotechnology

Experimental evolution of viruses: Microviridae as a model system

(2010) H. A. Wichman et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Landscape phage ligands for PC3 prostate carcinoma cells

(2010) P. K. Jayanna et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Engineering filamentous phage carriers to improve focusing of antibody responses against peptides

(2010) Nienke E. van Houten et al.   VACCINE

Genetically Engineered Phage Fibers and Coatings for Antibacterial Applications

(2009) Joan Y. Mao et al.   ADVANCED FUNCTIONAL MATERIALS

Progress in phage display: evolution of the technique and its applications

(2009) Tomaž Bratkovič   CELLULAR AND MOLECULAR LIFE SCIENCES

Metagenomic analysis of viruses in reclaimed water

(2009) Karyna Rosario et al.   ENVIRONMENTAL MICROBIOLOGY

Mimotope vaccination – from allergy to cancer

(2009) Regina Knittelfelder et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Genetically engineered phage harbouring the lethal catabolite gene activator protein gene with an inducer-independent promoter for biocontrol ofEscherichia coli

(2009) Zahra Moradpour et al.   FEMS MICROBIOLOGY LETTERS

Tumor-Specific Bacteriophages Induce Tumor Destruction through Activation of Tumor-Associated Macrophages

(2009) F. Eriksson et al.   JOURNAL OF IMMUNOLOGY

Exploring peptide mimics for the production of antibodies against discontinuous protein epitopes

(2009) Melita B. Irving et al.   MOLECULAR IMMUNOLOGY

Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy

(2009) T. K. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fabricating Genetically Engineered High-Power Lithium Ion Batteries Using Multiple Virus Genes

(2009) Y. J. Lee et al.   SCIENCE

Peptide mimotopes of rabies virus glycoprotein with immunogenic activity

(2009) Mehdi Houimel et al.   VACCINE

Sequential detection of Salmonella typhimurium and Bacillus anthracis spores using magnetoelastic biosensors

(2008) S. Huang et al.   BIOSENSORS & BIOELECTRONICS

Biomining with bacteriophage: Selectivity of displayed peptides for naturally occurring sphalerite and chalcopyrite

(2008) Susan B. Curtis et al.   BIOTECHNOLOGY AND BIOENGINEERING

Antigenic properties of HCMV peptides displayed by filamentous bacteriophages vs. synthetic peptides

(2008) Cristina Ulivieri et al.   IMMUNOLOGY LETTERS

Phage display for site-specific immunization and characterization of high-risk human papillomavirus specific E7 monoclonal antibodies

(2008) Maria Lidqvist et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Association of a Bacteriophage with Meningococcal Disease in Young Adults

(2008) Emmanuelle Bille et al.   PLoS One

Stamped microbattery electrodes based on self-assembled M13 viruses

(2008) K. T. Nam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inexpensive anti-cysticercosis vaccine: S3Pvac expressed in heat inactivated M13 filamentous phage proves effective against naturally acquired Taenia solium porcine cysticercosis

(2008) Julio Morales et al.   VACCINE

Immunogenicity and therapeutic efficacy of phage-displayed beta-amyloid epitopes

(2007) Marianna Esposito et al.   MOLECULAR IMMUNOLOGY