Vimentin Plays a Crucial Role in Fibroblast Ageing by Regulating Biophysical Properties and Cell Migration

Intermediate filaments control collective migration by restricting traction forces and sustaining cell–cell contacts

(2018) Chiara De Pascalis et al.   JOURNAL OF CELL BIOLOGY

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

(2017) Ok Hee Jeon et al.   NATURE MEDICINE

Vimentin fibers orient traction stress

(2017) Nancy Costigliola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

YAP regulates cell mechanics by controlling focal adhesion assembly

(2017) Giorgia Nardone et al.   Nature Communications

Actomyosin and vimentin cytoskeletal networks regulate nuclear shape, mechanics and chromatin organization

(2017) Michael C. Keeling et al.   Scientific Reports

Biophysical and biomolecular determination of cellular age in humans

(2017) Jude M. Phillip et al.   Nature Biomedical Engineering

Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction

(2016) Sirio Dupont   EXPERIMENTAL CELL RESEARCH

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β–Slug signaling

(2016) Fang Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined strategies for optimal detection of the contact point in AFM force-indentation curves obtained on thin samples and adherent cells

(2016) Núria Gavara   Scientific Reports

The Mechanobiology of Aging

(2015) Jude M. Phillip et al.   Annual Review of Biomedical Engineering

Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice

(2015) Hiroki Tanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intermediate Filaments Play a Pivotal Role in Regulating Cell Architecture and Function

(2015) Jason Lowery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The intrinsic stiffness of human trabecular meshwork cells increases with senescence

(2015) Joshua T. Morgan et al.   Oncotarget

Dissecting the contribution of actin and vimentin intermediate filaments to mechanical phenotype of suspended cells using high-throughput deformability measurements and computational modeling

(2014) Evgeny Gladilin et al.   JOURNAL OF BIOMECHANICS

A central role for vimentin in regulating repair function during healing of the lens epithelium

(2014) A. S. Menko et al.   MOLECULAR BIOLOGY OF THE CELL

Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix

(2014) R. J. Petrie et al.   SCIENCE

The Role of Vimentin Intermediate Filaments in Cortical and Cytoplasmic Mechanics

(2013) Ming Guo et al.   BIOPHYSICAL JOURNAL

YAP/TEAD-Mediated Transcription Controls Cellular Senescence

(2013) Q. Xie et al.   CANCER RESEARCH

Effects of long-term serial cell passaging on cell spreading, migration, and cell-surface ultrastructures of cultured vascular endothelial cells

(2013) Huanhuan Liao et al.   CYTOTECHNOLOGY

Age-Related Changes in the Mechanical Properties of Human Fibroblasts and Its Prospective Reversal After Anti-Wrinkle Tripeptide Treatment

(2013) Ida Dulińska-Molak et al.   International Journal of Peptide Research and Therapeutics

Silence of ezrin modifies migration and actin cytoskeleton rearrangements and enhances chemosensitivity of lung cancer cells in vitro

(2013) Qing-Yong Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Comparison of the viscoelastic properties of cells from different kidney cancer phenotypes measured with atomic force microscopy

(2013) L M Rebelo et al.   NANOTECHNOLOGY

The Influence of Physical and Physiological Cues on Atomic Force Microscopy-Based Cell Stiffness Assessment

(2013) Yu-Wei Chiou et al.   PLoS One

Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema

(2013) Marco Chilosi et al.   Translational Research

Determination of the elastic moduli of thin samples and adherent cells using conical atomic force microscope tips

(2012) Núria Gavara et al.   Nature Nanotechnology

Withaferin A Alters Intermediate Filament Organization, Cell Shape and Behavior

(2012) Boris Grin et al.   PLoS One

Pulmonary Artery Smooth Muscle Cell Senescence Is a Pathogenic Mechanism for Pulmonary Hypertension in Chronic Lung Disease

(2011) Hibo Noureddine et al.   CIRCULATION RESEARCH

Stiffening of Human Skin Fibroblasts with Age

(2011) Christian Schulze et al.   CLINICS IN PLASTIC SURGERY

Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer

(2011) C. Thangavel et al.   ENDOCRINE-RELATED CANCER

Depth-sensing analysis of cytoskeleton organization based on AFM data

(2011) Katarzyna Pogoda et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Vimentin is sufficient and required for wound repair and remodeling in alveolar epithelial cells

(2011) Micah R. Rogel et al.   FASEB JOURNAL

Vimentin organization modulates the formation of lamellipodia

(2011) Brian T. Helfand et al.   MOLECULAR BIOLOGY OF THE CELL

A role for actin arcs in the leading-edge advance of migrating cells

(2011) Dylan T. Burnette et al.   NATURE CELL BIOLOGY

Fibroblasts in three dimensional matrices: cell migration and matrix remodeling

(2010) Sangmyung Rhee   EXPERIMENTAL AND MOLECULAR MEDICINE

Efficient cell migration requires global chromatin condensation

(2010) G. Gerlitz et al.   JOURNAL OF CELL SCIENCE

Vimentin contributes to changes in chondrocyte stiffness in osteoarthritis

(2010) Dominik R. Haudenschild et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mechanics of the F-actin cytoskeleton

(2009) Jonathan Stricker et al.   JOURNAL OF BIOMECHANICS

Cell Stiffening in Response to External Stress is Correlated to Actin Recruitment

(2008) Delphine Icard-Arcizet et al.   BIOPHYSICAL JOURNAL

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL