DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

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Anti-Inflammatory MicroRNAs and Their Potential for Inflammatory Diseases Treatment

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Regulation of microRNA function in animals

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The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis

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Analysis of Microarray-Identified Genes and MicroRNAs Associated with Idiopathic Pulmonary Fibrosis

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NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages

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Re-evaluation of the roles ofDROSHA,Exportin 5, andDICERin microRNA biogenesis

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Pulmonary Macrophages: A New Therapeutic Pathway in Fibrosing Lung Disease?

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MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression

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AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity

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UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

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Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC

(2015) Seamus R. Morrone et al.   Nature Communications

MicroRNAs as potential targets for progressive pulmonary fibrosis

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Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

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Epigenetic Regulation ofmiR-17∼92Contributes to the Pathogenesis of Pulmonary Fibrosis

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Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung

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microRNA Regulation of Inflammatory Responses

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The CARD plays a critical role in ASC foci formation and inflammasome signalling

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Multiple Binding Sites on the Pyrin Domain of ASC Protein Allow Self-association and Interaction with NLRP3 Protein

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Crosstalk between TGF-β signaling and the microRNA machinery

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Age and sex dimorphisms contribute to the severity of bleomycin-induced lung injury and fibrosis

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An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

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MicroRNA in TLR signaling and endotoxin tolerance

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Integrating mechanisms of pulmonary fibrosis

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Comprehensive microRNA analysis in bleomycin-induced pulmonary fibrosis identifies multiple sites of molecular regulation

(2011) Ting Xie et al.   PHYSIOLOGICAL GENOMICS

Inhibition and Role of let-7d in Idiopathic Pulmonary Fibrosis

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miR-29 Is a Major Regulator of Genes Associated with Pulmonary Fibrosis

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The Inflammasomes

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Alternatively activated alveolar macrophages in pulmonary fibrosis—mediator production and intracellular signal transduction

(2010) Dmitri V. Pechkovsky et al.   CLINICAL IMMUNOLOGY

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

MicroRNA control of signal transduction

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Establishing Primary Adult Fibroblast Cultures From Rodents

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Pulmonary fibrosis: pathogenesis, etiology and regulation

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An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

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MicroRNAs: Novel Regulators During the Immune Response

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The Role of Inflammation in the Pathogenesis of Idiopathic Pulmonary Fibrosis

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