A Novel Multi-Target Small Molecule, LCC-09, Inhibits Stemness and Therapy-Resistant Phenotypes of Glioblastoma Cells by Increasing miR-34a and Deregulating the DRD4/Akt/mTOR Signaling Axis

Role of the nervous system in cancer metastasis

(2018) Nyanbol Kuol et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Current Challenges and Opportunities in Treating Glioblastoma

(2018) Andrea Shergalis et al.   PHARMACOLOGICAL REVIEWS

RANKL and RANK: From Mammalian Physiology to Cancer Treatment

(2018) Shuan Rao et al.   TRENDS IN CELL BIOLOGY

NFκB activation in differentiating glioblastoma stem-like cells is promoted by hyaluronic acid signaling through TLR4

(2018) Eva Ferrandez et al.   Scientific Reports

Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity

(2018) Kelly A Berg et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma

(2018) Shabierjiang JIAPAER et al.   NEUROLOGIA MEDICO-CHIRURGICA

NF-κB, Mesenchymal Differentiation and Glioblastoma

(2018) Bakhtiar Yamini   Cells

Overcoming therapeutic resistance in glioblastoma: the way forward

(2017) Satoru Osuka et al.   JOURNAL OF CLINICAL INVESTIGATION

Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization

(2017) Delphine Garnier et al.   NEURO-ONCOLOGY

Monoamines in glioblastoma: complex biology with therapeutic potential

(2017) Seamus Patrick Caragher et al.   NEURO-ONCOLOGY

Paired related homeobox 1 transactivates dopamine D2 receptor to maintain propagation and tumorigenicity of glioma-initiating cells

(2017) Yamu Li et al.   Journal of Molecular Cell Biology

Epigenetic dysregulation in neuroblastoma: A tale of miRNAs and DNA methylation

(2016) Federica Parodi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells

(2016) Sonam Dolma et al.   CANCER CELL

Temozolomide promotes genomic and phenotypic changes in glioblastoma cells

(2016) Aleksei A. Stepanenko et al.   Cancer Cell International

Impact of Blood-Brain Barrier Integrity on Tumor Growth and Therapy Response in Brain Metastases

(2016) M. Osswald et al.   CLINICAL CANCER RESEARCH

Restoring the oncosuppressor activity of microRNA-34a in glioblastoma using a polyglycerol-based polyplex

(2016) Paula Ofek et al.   Nanomedicine-Nanotechnology Biology and Medicine

Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance

(2016) Alessia Fidoamore et al.   Stem Cells International

Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF- B Signaling Pathway

(2015) N. Ohtsu et al.   CANCER RESEARCH

Discovery of 5-(2′,4′-difluorophenyl)-salicylanilides as new inhibitors of receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis

(2015) Chia-Chung Lee et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence

(2015) Brenda Auffinger et al.   Expert Review of Neurotherapeutics

The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence

(2015) Brenda Auffinger et al.   Expert Review of Neurotherapeutics

Epidemiologic and Molecular Prognostic Review of Glioblastoma

(2014) J. P. Thakkar et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Tumoral RANKL activates astrocytes that promote glioma cell invasion through cytokine signaling

(2014) Jun-Kyum Kim et al.   CANCER LETTERS

Tumor suppressive miRNA-34a suppresses cell proliferation and tumor growth of glioma stem cells by targeting Akt and Wnt signaling pathways

(2014) Sachin S. Rathod et al.   FEBS Open Bio

The role of microRNAs in the regulation of cancer stem cells

(2014) Ryou-u Takahashi et al.   Frontiers in Genetics

Shaping the interaction landscape of bioactive molecules

(2013) David Gfeller et al.   BIOINFORMATICS

Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells

(2013) M F Kendellen et al.   ONCOGENE

Aldehyde dehydrogenase inhibition generates a reactive dopamine metabolite autotoxic to dopamine neurons

(2013) Jonathan A. Doorn et al.   PARKINSONISM & RELATED DISORDERS

CD133 Is Essential for Glioblastoma Stem Cell Maintenance

(2013) Paola Brescia et al.   STEM CELLS

A Systematic Review of MicroRNA in Glioblastoma Multiforme: Micro-modulators in the Mesenchymal Mode of Migration and Invasion

(2012) Heidi G. Møller et al.   MOLECULAR NEUROBIOLOGY

Aldehyde dehydrogenase 1A1—a new mediator of resistance to temozolomide in glioblastoma

(2012) Andrea Schäfer et al.   NEURO-ONCOLOGY

miR-34 – a microRNA replacement therapy is headed to the clinic

(2012) Andreas G. Bader   Frontiers in Genetics

Chemoresistance of glioblastoma cancer stem cells - much more complex than expected

(2011) Dagmar Beier et al.   Molecular Cancer

RANKL inhibition—a new weapon against breast cancer?

(2010) Linda Koch   Nature Reviews Endocrinology

Establishing Intracranial Brain Tumor Xenografts With Subsequent Analysis of Tumor Growth and Response to Therapy using Bioluminescence Imaging

(2010) Tomoko Ozawa et al.   Jove-Journal of Visualized Experiments

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

(2009) Y. Li et al.   CANCER RESEARCH

Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors

(2009) Qinghai Liu et al.   JOURNAL OF NEURO-ONCOLOGY