Tumor suppressive miRNA-34a suppresses cell proliferation and tumor growth of glioma stem cells by targeting Akt and Wnt signaling pathways

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

Expression level of human miR-34a correlates with glioma grade and prognosis

(2013) Haifeng Gao et al.   JOURNAL OF NEURO-ONCOLOGY

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients

(2013) Shuwei Qiu et al.   Journal of Translational Medicine

Wnt3a mediated activation of Wnt/β-catenin signaling promotes tumor progression in glioblastoma

(2013) Navjot Kaur et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Tumour heterogeneity and cancer cell plasticity

(2013) Corbin E. Meacham et al.   NATURE

MiR-145 functions as a tumor-suppressive RNA by targeting Sox9 and adducin 3 in human glioma cells

(2013) S. B. Rani et al.   NEURO-ONCOLOGY

Detection of miR-34a Promoter Methylation in Combination with Elevated Expression of c-Met and  -Catenin Predicts Distant Metastasis of Colon Cancer

(2012) H. Siemens et al.   CLINICAL CANCER RESEARCH

Regulation of glycogen synthase kinase-3 beta (GSK-3β) by the Akt pathway in gliomas

(2012) Ryan J. Atkins et al.   JOURNAL OF CLINICAL NEUROSCIENCE

A Systematic Review of MicroRNA in Glioblastoma Multiforme: Micro-modulators in the Mesenchymal Mode of Migration and Invasion

(2012) Heidi G. Møller et al.   MOLECULAR NEUROBIOLOGY

Associations between microRNA expression and mesenchymal marker gene expression in glioblastoma

(2012) Xinlong Ma et al.   NEURO-ONCOLOGY

miR-34a Repression in Proneural Malignant Gliomas Upregulates Expression of Its Target PDGFRA and Promotes Tumorigenesis

(2012) Joachim Silber et al.   PLoS One

Integrative Subtype Discovery in Glioblastoma Using iCluster

(2012) Ronglai Shen et al.   PLoS One

Conditional Astroglial Rictor Overexpression Induces Malignant Glioma in Mice

(2012) Tariq Bashir et al.   PLoS One

MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme

(2012) J Lin et al.   Cell Death & Disease

MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma

(2011) Amanda Tivnan et al.   BMC CANCER

Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

(2011) Junlin Li et al.   BMC CANCER

MicroRNA-34a targets notch1 and inhibits cell proliferation in glioblastoma multiforme

(2011) Wen-Bo Li et al.   CANCER BIOLOGY & THERAPY

A Developmental Taxonomy of Glioblastoma Defined and Maintained by MicroRNAs

(2011) T.-M. Kim et al.   CANCER RESEARCH

mTOR complex 2 signaling and functions

(2011) Won Jun Oh et al.   CELL CYCLE

MicroRNAs as Regulators of Neural Stem Cell-Related Pathways in Glioblastoma Multiforme

(2011) Pilar González-Gómez et al.   MOLECULAR NEUROBIOLOGY

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

(2011) Can Liu et al.   NATURE MEDICINE

The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs

(2011) Dat T. Vo et al.   RNA Biology

MicroRNA-34a: A Novel Tumor Suppressor in p53-mutant Glioma Cell Line U251

(2010) Shihai Luan et al.   ARCHIVES OF MEDICAL RESEARCH

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

mTOR Complex Component Rictor Interacts with PKC  and Regulates Cancer Cell Metastasis

(2010) F. Zhang et al.   CANCER RESEARCH

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

(2010) Dmitri Lodygin et al.   CELL CYCLE

microRNA-34a is tumor suppressive in brain tumors and glioma stem cells

(2010) Fadila Guessous et al.   CELL CYCLE

TWIST1 promotes invasion through mesenchymal change in human glioblastoma

(2010) Svetlana A Mikheeva et al.   Molecular Cancer

Rictor regulates MMP-9 activity and invasion through Raf-1-MEK-ERK signaling pathway in glioma cells

(2010) Gowry Das et al.   MOLECULAR CARCINOGENESIS

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

(2009) Y. Li et al.   CANCER RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The miR-34 family in cancer and apoptosis

(2009) H Hermeking   CELL DEATH AND DIFFERENTIATION

Akt regulates skeletal development through GSK3, mTOR, and FoxOs

(2009) Satoshi Rokutanda et al.   DEVELOPMENTAL BIOLOGY

Rembrandt: Helping Personalized Medicine Become a Reality through Integrative Translational Research

(2009) S. Madhavan et al.   MOLECULAR CANCER RESEARCH

Proximal events in Wnt signal transduction

(2009) Stephane Angers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeted therapy for malignant glioma patients: Lessons learned and the road ahead

(2009) Tiffany T. Huang et al.   Neurotherapeutics

Brain cancer propagating cells: biology, genetics and targeted therapies

(2009) Costas G. Hadjipanayis et al.   TRENDS IN MOLECULAR MEDICINE

Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

(2008) Qing Ji et al.   BMC CANCER

A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

(2008) K. A. Cole et al.   MOLECULAR CANCER RESEARCH

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

The MYCN oncogene is a direct target of miR-34a

(2008) J S Wei et al.   ONCOGENE