4-Methylumbelliferone Inhibits Cancer Stem Cell Activation and Overcomes Chemoresistance in Ovarian Cancer
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
4-Methylumbelliferone Inhibits Cancer Stem Cell Activation and Overcomes Chemoresistance in Ovarian Cancer
Authors
Keywords
-
Journal
Cancers
Volume 11, Issue 8, Pages 1187
Publisher
MDPI AG
Online
2019-08-15
DOI
10.3390/cancers11081187
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Novel ex vivo ovarian cancer tissue explant assay for prediction of chemosensitivity and response to novel therapeutics
- (2018) Carmela Ricciardelli et al. CANCER LETTERS
- Targeting Glioblastoma Cells Expressing CD44 with Liposomes Encapsulating Doxorubicin and Displaying Chlorotoxin-IgG Fc Fusion Protein
- (2018) Hafizah Mahmud et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- 4-Methylumbelliferone Suppresses Hyaluronan Synthesis and Tumor Progression in SCID Mice Intra-abdominally Inoculated With Pancreatic Cancer Cells
- (2017) Hayato Nagase et al. PANCREAS
- Keratin 5 overexpression is associated with serous ovarian cancer recurrence and chemotherapy resistance
- (2017) Carmela Ricciardelli et al. Oncotarget
- Inhibition of hyaluronic acid formation sensitizes chronic myelogenous leukemia to treatment with doxorubicin
- (2016) Olga N Uchakina et al. GLYCOBIOLOGY
- Antitumor effects of 4-methylumbelliferone, a hyaluronan synthesis inhibitor, on malignant peripheral nerve sheath tumor
- (2016) Kunihiro Ikuta et al. INTERNATIONAL JOURNAL OF CANCER
- Relation between hyaluronan synthesis and cell morphology in ovarian clear cell carcinomas
- (2016) Noriko Kato et al. PATHOLOGY INTERNATIONAL
- Antitumor effects of the hyaluronan inhibitor 4-methylumbelliferone on pancreatic cancer
- (2016) Eri Yoshida et al. Oncology Letters
- Transketolase is upregulated in metastatic peritoneal implants and promotes ovarian cancer cell proliferation
- (2015) Carmela Ricciardelli et al. CLINICAL & EXPERIMENTAL METASTASIS
- The role of ABC transporters in ovarian cancer progression and chemoresistance
- (2015) M.P. Ween et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Dietary Supplement 4-Methylumbelliferone: An Effective Chemopreventive and Therapeutic Agent for Prostate Cancer
- (2015) Travis J. Yates et al. JNCI-Journal of the National Cancer Institute
- Accumulation of ALDH1-positive cells after neoadjuvant chemotherapy predicts treatment resistance and prognosticates poor outcome in ovarian cancer
- (2015) Tiyasha H. Ayub et al. Oncotarget
- Dietary Supplement 4-Methylumbelliferone: An Effective Chemopreventive and Therapeutic Agent for Prostate Cancer
- (2015) Travis J. Yates et al. JNCI-Journal of the National Cancer Institute
- 4-Methylumbelliferone Treatment and Hyaluronan Inhibition as a Therapeutic Strategy in Inflammation, Autoimmunity, and Cancer
- (2015) Nadine Nagy et al. Frontiers in Immunology
- Epigenetic Targeting of Ovarian Cancer Stem Cells
- (2014) Yinu Wang et al. CANCER RESEARCH
- Isolation and Characterization of Cancer Stem Cells from High-Grade Serous Ovarian Carcinomas
- (2014) Qi-zhi He et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Excessive Hyaluronan Production Promotes Acquisition of Cancer Stem Cell Signatures through the Coordinated Regulation of Twist and the Transforming Growth Factor β (TGF-β)-Snail Signaling Axis
- (2014) Theerawut Chanmee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 4-Methylumbelliferone inhibits ovarian cancer growth by suppressing thymidine phosphorylase expression
- (2014) Ryosuke Tamura et al. Journal of Ovarian Research
- Chemotherapy-induced hyaluronan production: a novel chemoresistance mechanism in ovarian cancer
- (2013) Carmela Ricciardelli et al. BMC CANCER
- Cancer Stem–like Cell Marker CD44 Promotes Bone Metastases by Enhancing Tumorigenicity, Cell Motility, and Hyaluronan Production
- (2013) Toru Hiraga et al. CANCER RESEARCH
- Hyaluronan synthesis inhibitor supplements the inhibitory effects of zoledronic acid on bone metastasis of lung cancer
- (2013) Naohisa Futamura et al. CLINICAL & EXPERIMENTAL METASTASIS
- Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer
- (2013) Pierre-Emmanuel Colombo et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Human leukemic cell lines synthesize hyaluronan to avoid senescence and resist chemotherapy
- (2013) S. L. Lompardia et al. GLYCOBIOLOGY
- Targeting hyaluronic acid production for the treatment of leukemia: Treatment with 4-methylumbelliferone leads to induction of MAPK-mediated apoptosis in K562 leukemia
- (2013) Olga N. Uchakina et al. LEUKEMIA RESEARCH
- Metabolic control of hyaluronan synthases
- (2013) Davide Vigetti et al. MATRIX BIOLOGY
- Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden
- (2013) Khalid Abubaker et al. Molecular Cancer
- Platinum-Sensitive Recurrence in Ovarian Cancer: The Role of Tumor Microenvironment
- (2013) Jeremy Chien et al. Frontiers in Oncology
- ALDH1-Bright Epithelial Ovarian Cancer Cells Are Associated with CD44 Expression, Drug Resistance, and Poor Clinical Outcome
- (2012) Yu-Chi Wang et al. AMERICAN JOURNAL OF PATHOLOGY
- Chick Chorioallantoic Membrane (CAM) Assay as an In Vivo Model to Study the Effect of Newly Identified Molecules on Ovarian Cancer Invasion and Metastasis
- (2012) Noor A. Lokman et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of Hyaluronan Synthesis Reduces Versican and Fibronectin Levels in Trabecular Meshwork Cells
- (2012) Kate E. Keller et al. PLoS One
- Inhibition of hyaluronan retention by 4-methylumbelliferone suppresses osteosarcoma cells in vitro and lung metastasis in vivo
- (2011) E Arai et al. BRITISH JOURNAL OF CANCER
- Hyaluronan Synthase HAS2 Promotes Tumor Progression in Bone by Stimulating the Interaction of Breast Cancer Stem-Like Cells with Macrophages and Stromal Cells
- (2011) H. Okuda et al. CANCER RESEARCH
- Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice
- (2011) F. Piccioni et al. GLYCOBIOLOGY
- Inhibition of hyaluronan synthesis in breast cancer cells by 4-methylumbelliferone suppresses tumorigenicity in vitro and metastatic lesions of bone in vivo
- (2011) Hiroshi Urakawa et al. INTERNATIONAL JOURNAL OF CANCER
- Role of Versican, Hyaluronan and CD44 in Ovarian Cancer Metastasis
- (2011) Miranda Ween et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile
- (2011) Ardian Latifi et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Inhibition of Oesophageal Squamous Cell Carcinoma Progression by in vivo Targeting of Hyaluronan Synthesis
- (2011) Sören Twarock et al. Molecular Cancer
- Reduction of Hyaluronan-CD44–Mediated Growth, Migration, and Cisplatin Resistance in Head and Neck Cancer Due to Inhibition of Rho Kinase and PI-3 Kinase Signaling
- (2010) Carlos Torre et al. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
- Global Levels of Specific Histone Modifications and an Epigenetic Gene Signature Predict Prostate Cancer Progression and Development
- (2010) T. Bianco-Miotto et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Antitumor Activity of Hyaluronic Acid Synthesis Inhibitor 4-Methylumbelliferone in Prostate Cancer Cells
- (2010) Vinata B. Lokeshwar et al. CANCER RESEARCH
- Versican induces a pro-metastatic ovarian cancer cell behavior which can be inhibited by small hyaluronan oligosaccharides
- (2010) Miranda P. Ween et al. CLINICAL & EXPERIMENTAL METASTASIS
- Hyaluronan in human malignancies
- (2010) R.K. Sironen et al. EXPERIMENTAL CELL RESEARCH
- Targeting Aldehyde Dehydrogenase Cancer Stem Cells in Ovarian Cancer
- (2010) C. N. Landen et al. MOLECULAR CANCER THERAPEUTICS
- 4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3
- (2009) Anne Kultti et al. EXPERIMENTAL CELL RESEARCH
- Hyaluronan-mediated CD44 Interaction with p300 and SIRT1 Regulates β-Catenin Signaling and NFκB-specific Transcription Activity Leading to MDR1 and Bcl-xLGene Expression and Chemoresistance in Breast Tumor Cells
- (2008) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hyaluronan-CD44 Interaction Activates Stem Cell Marker Nanog, Stat-3-mediated MDR1 Gene Expression, and Ankyrin-regulated Multidrug Efflux in Breast and Ovarian Tumor Cells
- (2008) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started