High numbers of activated helper T cells are associated with better clinical outcome in early stage vulvar cancer, irrespective of HPV or p53 status
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
High numbers of activated helper T cells are associated with better clinical outcome in early stage vulvar cancer, irrespective of HPV or p53 status
Authors
Keywords
Vulvar cancer, Tumor microenvironment, Immunotherapy, T cells, PD-1
Journal
Journal for ImmunoTherapy of Cancer
Volume 7, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-09-03
DOI
10.1186/s40425-019-0712-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
- (2019) Jérôme Galon et al. NATURE REVIEWS DRUG DISCOVERY
- Tbet-positive regulatory T cells accumulate in oropharyngeal cancers with ongoing tumor-specific type 1 T cell responses
- (2019) S. J. Santegoets et al. Journal for ImmunoTherapy of Cancer
- Clinical impact of PD-L1 and PD-1 expression in squamous cell cancer of the vulva
- (2019) Fabinshy Thangarajah et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Pembrolizumab in Recurrent Squamous Cell Carcinoma of the Vulva: Case Report and Review of the Literature
- (2018) Lisa B.E. Shields et al. GYNECOLOGIC AND OBSTETRIC INVESTIGATION
- Vulvar cancer: Two pathways with different localization and prognosis
- (2018) F. Hinten et al. GYNECOLOGIC ONCOLOGY
- Prognostic factors for local recurrence of squamous cell carcinoma of the vulva: A systematic review
- (2018) Nienke C. te Grootenhuis et al. GYNECOLOGIC ONCOLOGY
- Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy
- (2018) Marie-Claude Bourgeois-Daigneault et al. Science Translational Medicine
- Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16–Related Cancer
- (2018) Erminia Massarelli et al. JAMA Oncology
- Elements of cancer immunity and the cancer–immune set point
- (2017) Daniel S. Chen et al. NATURE
- Tumoral PD-L1 expression defines a subgroup of poor-prognosis vulvar carcinomas with non-viral etiology
- (2017) Thomas Hecking et al. Oncotarget
- Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
- (2017) Angel Garcia-Diaz et al. Cell Reports
- Hierarchical Stochastic Neighbor Embedding
- (2016) N. Pezzotti et al. COMPUTER GRAPHICS FORUM
- The host STING pathway at the interface of cancer and immunity
- (2016) Leticia Corrales et al. JOURNAL OF CLINICAL INVESTIGATION
- Complementing T-cell Function: An Inhibitory Role of the Complement System in T-cell-Mediated Antitumor Immunity
- (2016) W. Peng et al. Cancer Discovery
- De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute
- (2016) I. Mellman et al. Cancer Immunology Research
- Genetic Basis for PD-L1 Expression in Squamous Cell Carcinomas of the Cervix and Vulva
- (2016) Brooke E. Howitt et al. JAMA Oncology
- Squamous Cell Carcinoma of the Vulva
- (2015) Fei Dong et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry
- (2015) Saskia J. A. M. Santegoets et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
- (2015) Stefani Spranger et al. NATURE
- Alterations in classical and nonclassical HLA expression in recurrent and progressive HPV-induced usual vulvar intraepithelial neoplasia and implications for immunotherapy
- (2014) E.M.G. van Esch et al. INTERNATIONAL JOURNAL OF CANCER
- Intraepithelial macrophage infiltration is related to a high number of regulatory T cells and promotes a progressive course of HPV-induced vulvar neoplasia
- (2014) Edith M.G. van Esch et al. INTERNATIONAL JOURNAL OF CANCER
- Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival
- (2014) Edith M.G. van Esch et al. INTERNATIONAL JOURNAL OF CANCER
- Automated identification of stratifying signatures in cellular subpopulations
- (2014) Robert V. Bruggner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Subtypes of cytotoxic lymphocytes and natural killer cells infiltrating cancer nests correlate with prognosis in patients with vulvar squamous cell carcinoma
- (2013) Jacek Jan Sznurkowski et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Worldwide human papillomavirus genotype attribution in over 2000 cases of intraepithelial and invasive lesions of the vulva
- (2013) Silvia de Sanjosé et al. EUROPEAN JOURNAL OF CANCER
- Investigating a cluster of vulvar cancer in young women: a cross-sectional study of genital human papillomavirus prevalence
- (2012) Alice R Rumbold et al. BMC INFECTIOUS DISEASES
- Topical TLR7 Agonist Imiquimod Can Induce Immune-Mediated Rejection of Skin Metastases in Patients with Breast Cancer
- (2012) S. Adams et al. CLINICAL CANCER RESEARCH
- Induction of tumoricidal function in CD4+T cells is associated with concomitant memory and terminally differentiated phenotype
- (2012) Daniel Hirschhorn-Cymerman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape
- (2012) J. M. Taube et al. Science Translational Medicine
- Expression of indoleamine 2,3-dioxygenase predicts shorter survival in patients with vulvar squamous cell carcinoma (vSCC) not influencing on the recruitment of FOXP3-expressing regulatory T cells in cancer nests
- (2011) Jacek J. Sznurkowski et al. GYNECOLOGIC ONCOLOGY
- Status of cellular immunity lacks prognostic significance in vulvar squamous carcinoma
- (2011) R.A. de Jong et al. GYNECOLOGIC ONCOLOGY
- Should we consider cancer/testis antigens NY-ESO-1, MAGE-A4 and MAGE-A1 as potential targets for immunotherapy in vulvar squamous cell carcinoma?
- (2011) Jacek J Sznurkowski et al. HISTOPATHOLOGY
- Prognostic Significance of CD4+ and CD8+ T Cell Infiltration Within Cancer Cell Nests in Vulvar Squamous Cell Carcinoma
- (2011) Jacek Jan Sznurkowski et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- An Unexpectedly Large Polyclonal Repertoire of HPV-Specific T Cells Is Poised for Action in Patients with Cervical Cancer
- (2010) Peggy J. de Vos van Steenwijk et al. CANCER RESEARCH
- The Etiologic Role of HPV in Vulvar Squamous Cell Carcinoma Fine Tuned
- (2009) H. P. van de Nieuwenhof et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Treatment of Vulvar Intraepithelial Neoplasia with Topical Imiquimod
- (2008) Manon van Seters et al. NEW ENGLAND JOURNAL OF MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started