PKCα–GSK3β–NF-κB signaling pathway and the possible involvement of TRIM21 in TRAIL-induced apoptosis

Systems Biology Strategy Reveals PKCδ is Key for Sensitizing TRAIL-Resistant Human Fibrosarcoma

(2015) Kentaro Hayashi et al.   Frontiers in Immunology

Nuclear protein kinase C isoforms and apoptosis

(2015) AM Martelli et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Ser9-phosphorylated GSK3β induced by 14-3-3ζ actively antagonizes cell apoptosis in a NF-κB dependent manner

(2014) Xuejuan Gao et al.   Biochemistry and Cell Biology

Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells

(2014) Huan-Tian Zhang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

TRIM family proteins: emerging class of RING E3 ligases as regulator of NF-κB pathway

(2014) Dhanendra Tomar et al.   BIOLOGY OF THE CELL

The Molecular Mechanisms of TRAIL Resistance in Cancer Cells: Help in Designing New Drugs

(2014) Feng Wang et al.   CURRENT PHARMACEUTICAL DESIGN

14-3-3ζ Reduces DNA Damage by Interacting With and Stabilizing Proliferating Cell Nuclear Antigen

(2014) Xuejuan Gao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Interruption of PKC-ι Signaling and TRAIL Combination Therapy Against Glioblastoma Cells

(2014) Andrea N. McCray et al.   NEUROCHEMICAL RESEARCH

Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells

(2014) J-S Zhang et al.   Cell Death & Disease

Protein kinase C pharmacology: refining the toolbox

(2013) Alyssa X. Wu-zhang et al.   BIOCHEMICAL JOURNAL

Identification and analysis of glycogen synthase kinase 3 beta1 interactome

(2013) Xuejuan Gao et al.   CELL BIOLOGY INTERNATIONAL

Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family

(2013) K Azijli et al.   CELL DEATH AND DIFFERENTIATION

Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions

(2012) Hongqin Zhuang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Celecoxib Promotes c-FLIP Degradation through Akt-Independent Inhibition of GSK3

(2011) S. Chen et al.   CANCER RESEARCH

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

(2011) Theonie Anastassiadis et al.   NATURE BIOTECHNOLOGY

NF-κB targeting by way of IKK inhibition sensitizes lung cancer cells to adenovirus delivery of TRAIL

(2010) Cigdem Aydin et al.   BMC CANCER

Downregulation of active IKKβ by Ro52-mediated autophagy

(2010) Motoko Niida et al.   MOLECULAR IMMUNOLOGY

Ro52-mediated Monoubiquitination of IKK  Down-regulates NF- B Signalling

(2009) K. Wada et al.   JOURNAL OF BIOCHEMISTRY

Glycogen synthase kinase-3 inhibitors augment TRAIL-induced apoptotic death in human hepatoma cells

(2008) Eléonore Beurel et al.   BIOCHEMICAL PHARMACOLOGY

Glycogen synthase kinase 3β (GSK3β) in tumorigenesis and cancer chemotherapy

(2008) Jia Luo   CANCER LETTERS

Glycogen Synthase Kinase-3 Inhibition Induces Glioma Cell Death through c-MYC, Nuclear Factor- B, and Glucose Regulation

(2008) S. Kotliarova et al.   CANCER RESEARCH

Apoptosis resistance in epithelial tumors is mediated by tumor-cell-derived interleukin-4

(2008) M Todaro et al.   CELL DEATH AND DIFFERENTIATION

PKC alpha protein but not kinase activity is critical for glioma cell proliferation and survival

(2008) Angus J. Cameron et al.   INTERNATIONAL JOURNAL OF CANCER

Protein kinase Cɛ confers resistance of MCF-7 cells to TRAIL by Akt-dependent activation of Hdm2 and downregulation of p53

(2008) E Shankar et al.   ONCOGENE