Bacterial RNA Contributes to the Down-Modulation of MHC-II Expression on Monocytes/Macrophages Diminishing CD4+ T Cell Responses

Inhibition of antigen presentation by Brucella: many more than many ways

(2019) Paula Barrionuevo et al.   MICROBES AND INFECTION

Correction: Trypanosoma cruzi-specific IFN-γ-producing cells in chronic Chagas disease associate with a functional IL-7/IL-7R axis

(2019) María A. Natale et al.   PLoS Neglected Tropical Diseases

B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway

(2017) M. Ayelén Milillo et al.   PLoS Pathogens

Inhibition of MHC-I by Brucella abortus is an early event during infection and involves EGFR pathway

(2016) Lis N Velásquez et al.   IMMUNOLOGY AND CELL BIOLOGY

ABrucellaspp. Protease Inhibitor Limits Antigen Lysosomal Proteolysis, Increases Cross-Presentation, and Enhances CD8+T Cell Responses

(2016) Lorena M. Coria et al.   JOURNAL OF IMMUNOLOGY

Identification of Immune Effectors Essential to the Control of Primary and Secondary Intranasal Infection withBrucella melitensisin Mice

(2016) Delphine Hanot Mambres et al.   JOURNAL OF IMMUNOLOGY

Brucella abortus down-regulates MHC class II by the IL-6-dependent inhibition of CIITA through the downmodulation of IFN regulatory factor-1 (IRF-1)

(2016) Lis N. Velásquez et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology

(2015) Karin Pelka et al.   IMMUNOLOGICAL REVIEWS

Cutting Edge: DNase II Deficiency Prevents Activation of Autoreactive B Cells by Double-Stranded DNA Endogenous Ligands

(2015) Sudesh Pawaria et al.   JOURNAL OF IMMUNOLOGY

Synergistic activation of Toll-like receptor 8 by two RNA degradation products

(2015) Matthias Geyer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Toll-like receptor 8 senses degradation products of single-stranded RNA

(2015) Hiromi Tanji et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNase II-dependent DNA digestion is required for DNA sensing by TLR9

(2015) Mei Po Chan et al.   Nature Communications

Synergistic activation of Toll-like receptor 8 by two RNA degradation products

(2015) Matthias Geyer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Toll-like receptor 8 senses degradation products of single-stranded RNA

(2015) Hiromi Tanji et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes

(2013) Jorge L. Cervantes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Selective Subversion of Autophagy Complexes Facilitates Completion of the Brucella Intracellular Cycle

(2012) Tregei Starr et al.   Cell Host & Microbe

Brucella abortusinduces intracellular retention of MHC-I molecules in human macrophages down-modulating cytotoxic CD8+T cell responses

(2012) Paula Barrionuevo et al.   CELLULAR MICROBIOLOGY

Crucial Role of Gamma Interferon-Producing CD4+Th1 Cells but Dispensable Function of CD8+T Cell, B Cell, Th2, and Th17 Responses in the Control of Brucella melitensis Infection in Mice

(2012) Marie-Alice Vitry et al.   INFECTION AND IMMUNITY

In Situ Microscopy Analysis Reveals Local Innate Immune Response Developed around Brucella Infected Cells in Resistant and Susceptible Mice

(2012) Richard Copin et al.   PLoS Pathogens

The TLR7/8 ligand resiquimod targets monocyte-derived dendritic cell differentiation via TLR8 and augments functional dendritic cell generation

(2011) Holger Hackstein et al.   CELLULAR IMMUNOLOGY

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

(2011) Leif E. Sander et al.   NATURE

Exposure to HIV-1-encoded Toll-like receptor 8 ligands enhances monocyte response to microbial encoded Toll-like receptor 2/4 ligands

(2010) Marianne W Mureith et al.   AIDS

Cell-mediated immunity in human brucellosis

(2010) Panagiotis Skendros et al.   MICROBES AND INFECTION

Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells

(2009) S. M. Makela et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Brucella lipoproteins mimic dendritic cell maturation induced by Brucella abortus

(2008) Astrid Zwerdling et al.   MICROBES AND INFECTION

Brucella Intracellular Replication Requires Trafficking Through the Late Endosomal/Lysosomal Compartment

(2008) Tregei Starr et al.   TRAFFIC