DNase II-dependent DNA digestion is required for DNA sensing by TLR9

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9

(2014) R. E. Rigby et al.   EMBO JOURNAL

Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses

(2013) L. Huang et al.   JOURNAL OF IMMUNOLOGY

Molecular Basis of DNA Recognition in the Immune System

(2013) M. K. Atianand et al.   JOURNAL OF IMMUNOLOGY

Biogenesis and Proteolytic Processing of Lysosomal DNase II

(2013) Susumu Ohkouchi et al.   PLoS One

An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing

(2013) Masahiro Onji et al.   Nature Communications

Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease

(2012) Alevtina Gall et al.   IMMUNITY

STING manifests self DNA-dependent inflammatory disease

(2012) J. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

(2011) Glen N Barber   CURRENT OPINION IN IMMUNOLOGY

Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3

(2010) M. Sasai et al.   SCIENCE

Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8

(2009) Dipyaman Ganguly et al.   JOURNAL OF EXPERIMENTAL MEDICINE