A Broad-Spectrum ROS-Eliminating Material for Prevention of Inflammation and Drug-Induced Organ Toxicity

A myeloperoxidase-responsive and biodegradable luminescent material for real-time imaging of inflammatory diseases

(2017) Jiawei Guo et al.   Materials Today

Neurovascular Unit Protection From Cerebral Ischemia–Reperfusion Injury by Radical-Containing Nanoparticles in Mice

(2017) Hisayuki Hosoo et al.   STROKE

Tempol, a Superoxide Dismutase Mimetic Agent, Inhibits Superoxide Anion-Induced Inflammatory Pain in Mice

(2017) Catia C. F. Bernardy et al.   Biomed Research International

Bilirubin Nanoparticles as a Nanomedicine for Anti-inflammation Therapy

(2016) Yonghyun Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis

(2016) Shibin Feng et al.   BIOMATERIALS

A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease

(2016) Qixiong Zhang et al.   BIOMATERIALS

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

Tempol, a Membrane-Permeable Radical Scavenger, Exhibits Anti-Inflammatory and Cardioprotective Effects in the Cerulein-Induced Pancreatitis Rat Model

(2016) Andrzej Marciniak et al.   Oxidative Medicine and Cellular Longevity

Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?

(2016) Subrata Kumar Biswas   Oxidative Medicine and Cellular Longevity

The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE−/− mice

(2015) Christine H.J. Kim et al.   ATHEROSCLEROSIS

p-Hydroxybenzyl alcohol-containing biodegradable nanoparticle improves functional blood flow through angiogenesis in a mouse model of hindlimb ischemia

(2015) Byung-Ryul Cho et al.   BIOMATERIALS

Mitochondrial Reactive Oxygen Species at the Heart of the Matter: New Therapeutic Approaches for Cardiovascular Diseases

(2015) O. S. Kornfeld et al.   CIRCULATION RESEARCH

Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis

(2015) Akiko Eguchi et al.   Nanomedicine

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Anti-inflammatory therapies for atherosclerosis

(2015) Magnus Bäck et al.   Nature Reviews Cardiology

Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo

(2015) Daniel R. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Are Anti-inflammatory Therapies Viable Treatments for Psychiatric Disorders?

(2015) Andrew H. Miller et al.   JAMA Psychiatry

Nanoparticles with Dual Responses to Oxidative Stress and Reduced pH for Drug Release and Anti-inflammatory Applications

(2014) Hsiao-Lan Pu et al.   ACS Nano

Therapeutic use of H2O2-responsive anti-oxidant polymer nanoparticles for doxorubicin-induced cardiomyopathy

(2014) Seunggyu Park et al.   BIOMATERIALS

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing

(2014) Adam J Shuhendler et al.   NATURE BIOTECHNOLOGY

Reactive Oxygen Species-Scavenging Nanomedicines for the Treatment of Oxidative Stress Injuries

(2014) Toru Yoshitomi et al.   Advanced Healthcare Materials

Biocompatible Reactive Oxygen Species (ROS)-Responsive Nanoparticles as Superior Drug Delivery Vehicles

(2014) Dinglin Zhang et al.   Advanced Healthcare Materials

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

(2013) Huajun Jin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Suppression of NSAID-induced small intestinal inflammation by orally administered redox nanoparticles

(2013) Sha Sha et al.   BIOMATERIALS

Hydrogen peroxide-responsive copolyoxalate nanoparticles for detection and therapy of ischemia–reperfusion injury

(2013) Dongwon Lee et al.   JOURNAL OF CONTROLLED RELEASE

Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

(2013) I. Tabas et al.   SCIENCE

Evolution of Inflammatory Diseases

(2012) Daniel Okin et al.   CURRENT BIOLOGY

Biocompatible Polymeric Nanoparticles Degrade and Release Cargo in Response to Biologically Relevant Levels of Hydrogen Peroxide

(2012) Caroline de Gracia Lux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dendrimer-Based Postnatal Therapy for Neuroinflammation and Cerebral Palsy in a Rabbit Model

(2012) S. Kannan et al.   Science Translational Medicine

An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals

(2011) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease

(2011) Patrizia Mecocci et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reactive oxygen species in cardiovascular disease

(2011) Koichi Sugamura et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nanotechnology for therapy and imaging of liver diseases

(2011) L. Harivardhan Reddy et al.   JOURNAL OF HEPATOLOGY

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(2011) Jochen Grommes et al.   MOLECULAR MEDICINE

A Phosphorus-Based Dendrimer Targets Inflammation and Osteoclastogenesis in Experimental Arthritis

(2011) M. Hayder et al.   Science Translational Medicine

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammation, Immunity, and Hypertension

(2010) David G. Harrison et al.   HYPERTENSION

Acute Lung Injury: Epidemiology, Pathogenesis, and Treatment

(2010) Elizabeth R. Johnson et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

A Biocompatible Oxidation-Triggered Carrier Polymer with Potential in Therapeutics

(2010) Kyle E. Broaders et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dendritic polyglycerol sulfates as multivalent inhibitors of inflammation

(2010) J. Dernedde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of Core−Shell-Type Nanoparticles Carrying Stable Radicals in the Core

(2009) Toru Yoshitomi et al.   BIOMACROMOLECULES

Risk of Lymphoma Associated With Combination Anti–Tumor Necrosis Factor and Immunomodulator Therapy for the Treatment of Crohn's Disease: A Meta-Analysis

(2009) Corey A. Siegel et al.   Clinical Gastroenterology and Hepatology

Colectomy Rate Comparison After Treatment of Ulcerative Colitis With Placebo or Infliximab

(2009) William J. Sandborn et al.   GASTROENTEROLOGY

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Chemistry and Antihypertensive Effects of Tempol and Other Nitroxides

(2008) C. S. Wilcox et al.   PHARMACOLOGICAL REVIEWS