The Inflammatory Tissue Microenvironment in IBD

Control of IFN- A by CD73: Implications for Mucosal Inflammation

(2014) N. A. Louis et al.   JOURNAL OF IMMUNOLOGY

Impairment of adenosine A3 receptor activity disrupts neutrophil migratory capacity and impacts innate immune function in vivo

(2012) Matt Butler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD73 Is Critical for the Resolution of Murine Colonic Inflammation

(2012) Margaret S. Bynoe et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

(2012) E. T. Clambey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery

(2011) Sean P. Colgan et al.   Annual Review of Physiology

Hypoxia and Metabolic Factors That Influence Inflammatory Bowel Disease Pathogenesis

(2011) Louise E. Glover et al.   GASTROENTEROLOGY

Antimicrobial Aspects of Inflammatory Resolution in the Mucosa: A Role for Proresolving Mediators

(2011) E. L. Campbell et al.   JOURNAL OF IMMUNOLOGY

Hypoxia: an alarm signal during intestinal inflammation

(2010) Sean P. Colgan et al.   Nature Reviews Gastroenterology & Hepatology

Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification

(2010) E. L. Campbell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclooxygenase-2 and Hypoxia-Inducible Factor-1α protein expression is related to inflammation, and up-regulated since the early steps of colorectal carcinogenesis

(2009) Francesco Mariani et al.   CANCER LETTERS

Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia

(2009) Shinae Kizaka-Kondoh et al.   CANCER SCIENCE

New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC

(2009) Leszek Rybaczyk et al.   INFLAMMATORY BOWEL DISEASES

HIF-2α, but not HIF-1α, promotes iron absorption in mice

(2009) Maria Mastrogiannaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Contribution of Adenosine A2B Receptors to Inflammatory Parameters of Experimental Colitis

(2009) J.-S. Frick et al.   JOURNAL OF IMMUNOLOGY

Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia

(2009) Peter Rosenberger et al.   NATURE IMMUNOLOGY

Enterocyte Shedding and Epithelial Lining Repair Following Ischemia of the Human Small Intestine Attenuate Inflammation

(2009) Robert A. Matthijsen et al.   PLoS One

CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease

(2009) D. J. Friedman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-Adjuvanting Lipopeptide Vaccines

(2008) Peter Moyle et al.   CURRENT MEDICINAL CHEMISTRY

Hypoxia-Inducible Factor–Dependent Repression of Equilibrative Nucleoside Transporter 2 Attenuates Mucosal Inflammation During Intestinal Hypoxia

(2008) Julio C. Morote–Garcia et al.   GASTROENTEROLOGY

Interdependent roles for hypoxia inducible factor and nuclear factor-κB in hypoxic inflammation

(2008) Cormac T. Taylor   JOURNAL OF PHYSIOLOGY-LONDON

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

Priming of the neutrophil NADPH oxidase activation: role of p47phox phosphorylation and NOX2 mobilization to the plasma membrane

(2008) Jamel El-Benna et al.   Seminars in Immunopathology

Applications of Nitroimidazole In Vivo Hypoxia Imaging in Ischemic Stroke

(2008) Masashi Takasawa et al.   STROKE

Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus

(2007) C N Serhan et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

(2007) Eoin P. Cummins et al.   GASTROENTEROLOGY

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

(2007) Andreas Robinson et al.   GASTROENTEROLOGY