Hypoxia Enhances Endothelial Intercellular Adhesion Molecule 1 Protein Level Through Upregulation of Arginase Type II and Mitochondrial Oxidative Stress

Hypoxia Triggers SENP1 (Sentrin-Specific Protease 1) Modulation of KLF15 (Kruppel-Like Factor 15) and Transcriptional Regulation of Arg2 (Arginase 2) in Pulmonary EndotheliumHighlights

(2018) Deepesh Pandey et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Roles of Hypoxia Signaling in the Pathogenesis of Cardiovascular Diseases

(2017) Hajime Abe et al.   Journal of Atherosclerosis and Thrombosis

Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response

(2017) Hemantkumar Chavan et al.   Oxidative Medicine and Cellular Longevity

Obstructive Sleep Apnea and Hallmarks of Aging

(2017) Laetitia S. Gaspar et al.   TRENDS IN MOLECULAR MEDICINE

Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell ActivationHighlights

(2016) Xinyuan Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HIF2α–arginase axis is essential for the development of pulmonary hypertension

(2016) Andrew S. Cowburn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functions of Arginase Isoforms in Macrophage Inflammatory Responses: Impact on Cardiovascular Diseases and Metabolic Disorders

(2014) Zhihong Yang et al.   Frontiers in Immunology

Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology

(2013) Gregg L. Semenza   Annual Review of Pathology-Mechanisms of Disease

Arginase‐II Induces Vascular Smooth Muscle Cell Senescence and Apoptosis Through p66Shc and p53 Independently of Its l ‐Arginine Ureahydrolase Activity: Implications for Atherosclerotic Plaque Vulnerability

(2013) Yuyan Xiong et al.   Journal of the American Heart Association

Arginase: The Emerging Therapeutic Target for Vascular Oxidative Stress and Inflammation

(2013) Zhihong Yang et al.   Frontiers in Immunology

Positive crosstalk between arginase-II and S6K1 in vascular endothelial inflammation and aging

(2012) Gautham Yepuri et al.   AGING CELL

Dynamic Change of Chromatin Conformation in Response to Hypoxia Enhances the Expression of GLUT3 (SLC2A3) by Cooperative Interaction of Hypoxia-Inducible Factor 1 and KDM3A

(2012) I. Mimura et al.   MOLECULAR AND CELLULAR BIOLOGY

Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis

(2012) Xiu‐Fen Ming et al.   Journal of the American Heart Association

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium

(2011) C.P. Prieto et al.   PLACENTA

Hypoxic upregulation of arginase II in human lung endothelial cells

(2010) Karina Krotova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Differential activation and antagonistic function of HIF-  isoforms in macrophages are essential for NO homeostasis

(2010) N. Takeda et al.   GENES & DEVELOPMENT

The role of hypoxia in atherosclerosis

(2009) Lillemor Mattsson Hultén et al.   CURRENT OPINION IN LIPIDOLOGY

Mechanisms of intermittent hypoxia induced hypertension

(2009) Laura V. González Bosc et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hypoxia-Inducible Factor-1α and -2α Additively Promote Endothelial Vasculogenic Properties

(2008) Jeremy Ben-Shoshan et al.   JOURNAL OF VASCULAR RESEARCH

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE