Hydroxycamptothecin Inhibits Peritendinous Adhesion via the Endoplasmic Reticulum Stress-Dependent Apoptosis

Hydroxycamptothecin Prevents Fibrotic Pathways in Fibroblasts In Vitro

(2019) Zhixiao Yao et al.   IUBMB LIFE

Transforming growth factor β (TGFβ) and related molecules in chronic kidney disease (CKD)

(2019) Pacific Huynh et al.   CLINICAL SCIENCE

Protective Effects of Activated Myofibroblasts in the Pressure-Overloaded Myocardium Are Mediated Through Smad-Dependent Activation of a Matrix-Preserving Program

(2019) Ilaria Russo et al.   CIRCULATION RESEARCH

The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2α and IRE1α/XBP-1 in colorectal cancer

(2019) Yi-Jye Chern et al.   Cell Death & Disease

miR-103/107 promote ER stress-mediated apoptosis via targeting the Wnt3a/β-catenin/ATF6 pathway in preadipocytes

(2018) Zhenzhen Zhang et al.   JOURNAL OF LIPID RESEARCH

Rapamycin Protects Against Peritendinous Fibrosis Through Activation of Autophagy

(2018) Wei Zheng et al.   Frontiers in Pharmacology

Mucoadhesive Cationic Polypeptide Nanogel with Enhanced Penetration for Efficient Intravesical Chemotherapy of Bladder Cancer

(2018) Hui Guo et al.   Advanced Science

Decorin counteracts disease progression in mice with recessive dystrophic epidermolysis bullosa

(2018) Francesca Cianfarani et al.   MATRIX BIOLOGY

Gene Silencing via PDA/ERK2-siRNA-Mediated Electrospun Fibers for Peritendinous Antiadhesion

(2018) Shen Liu et al.   Advanced Science

Atrial natriuretic peptide attenuates endoplasmic reticulum stress in experimental acute pancreatitis

(2018) Ana Paula Courreges et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

ER stress and the unfolded protein response in neurodegeneration

(2017) Claudio Hetz et al.   Nature Reviews Neurology

RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation and apoptosis

(2017) Shuai Chen et al.   Cell Death & Disease

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

(2016) Giovanni Musso et al.   NATURE REVIEWS DRUG DISCOVERY

Biologics for tendon repair

(2015) Denitsa Docheva et al.   ADVANCED DRUG DELIVERY REVIEWS

Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1

(2015) Meredith L. Sosulski et al.   AGING CELL

ER Stress and Angiogenesis

(2015) François Binet et al.   Cell Metabolism

Inositol-requiring protein 1 – X-box-binding protein 1 pathway promotes epithelial–mesenchymal transition via mediating snail expression in pulmonary fibrosis

(2015) Xiao-Ting Mo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Down-regulating ERK1/2 and SMAD2/3 phosphorylation by physical barrier of celecoxib-loaded electrospun fibrous membranes prevents tendon adhesions

(2014) Shichao Jiang et al.   BIOMATERIALS

Autophagy Regulates TGF-  Expression and Suppresses Kidney Fibrosis Induced by Unilateral Ureteral Obstruction

(2014) Y. Ding et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress

(2012) Richard Jäger et al.   BIOLOGY OF THE CELL

Endoplasmic reticulum dysfunction in neurological disease

(2012) Benoit D Roussel et al.   LANCET NEUROLOGY

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Tendon Healing In Vivo: Effect of Mannose-6-phosphate on Flexor Tendon Adhesion Formation

(2012) Changsuo Xia et al.   ORTHOPEDICS

Gene Expression Analysis of the Pleiotropic Effects of TGF-β1 in an In Vitro Model of Flexor Tendon Healing

(2012) Youssef M. Farhat et al.   PLoS One

Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+and ER/Golgi Membrane Network

(2011) Can E. Senkal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduction of Peritendinous Adhesions by Hydrogel Containing Biocompatible Phospholipid Polymer MPC for Tendon Repair

(2011) Noriyuki Ishiyama et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Application of liposome-encapsulated hydroxycamptothecin in the prevention of epidural scar formation in New Zealand white rabbits

(2011) Jun Yang et al.   Spine Journal

The prevention of peritendinous adhesions by a phospholipid polymer hydrogel formed in situ by spontaneous intermolecular interactions

(2010) Noriyuki Ishiyama et al.   BIOMATERIALS

Covalently Combining Carbon Nanotubes with Anticancer Agent: Preparation and Antitumor Activity

(2009) Wei Wu et al.   ACS Nano

Divergent Effects of PERK and IRE1 Signaling on Cell Viability

(2009) Jonathan H. Lin et al.   PLoS One

ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum

(2008) Yusuke Adachi et al.   CELL STRUCTURE AND FUNCTION

The effect of 10-hydroxycamptothecine in preventing fibroblast proliferation and epidural scar adhesion after laminectomy in rats

(2008) Yu Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY